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Classes (such as dimObj) that can hold information from multiple types of methods use the misc slot to hold additional information specific to each method. Information may be stored within as S3 structures.

Value

slot for miscellaneous information

Examples

g <- GiottoData::loadSubObjectMini("dimObj")

slot(g, "misc")
#> $eigenvalues
#>   [1] 33.2534135 32.0046063 30.0502213 23.4352729 14.9873873 14.4036736
#>   [7] 11.8499793 10.6893086  9.3040152  6.9800585  6.8538084  6.0485295
#>  [13]  5.7915560  5.1138968  4.9417237  4.7024725  4.3698509  4.1615473
#>  [19]  3.9581798  3.5429980  3.4268141  3.3099700  3.2350908  3.1648805
#>  [25]  3.0439582  2.9064535  2.8524063  2.7202686  2.6799304  2.5689859
#>  [31]  2.5279120  2.4568203  2.4413820  2.4043215  2.2542061  2.2058793
#>  [37]  2.1896105  2.1608223  2.1332721  2.0909430  2.0288850  1.9923129
#>  [43]  1.9176801  1.8699125  1.8353129  1.7768831  1.7700422  1.7509328
#>  [49]  1.7226019  1.6894990  1.6530223  1.6411241  1.5851496  1.5687056
#>  [55]  1.5454645  1.5241935  1.4727217  1.4685526  1.4528981  1.4055974
#>  [61]  1.3715253  1.3659691  1.3286971  1.2883263  1.2804195  1.2507976
#>  [67]  1.2475448  1.2363812  1.1837924  1.1801315  1.1659735  1.1448418
#>  [73]  1.1201655  1.0999292  1.0838246  1.0546067  1.0483329  1.0319266
#>  [79]  0.9870703  0.9835202  0.9510675  0.9296043  0.9225639  0.9045214
#>  [85]  0.8797710  0.8550994  0.8356013  0.8292998  0.8066431  0.8016031
#>  [91]  0.7671520  0.7594730  0.7402408  0.7279798  0.7131876  0.6834403
#>  [97]  0.6823937  0.6489129  0.6446519  0.6206416
#> 
#> $loadings
#>                  Dim.1         Dim.2         Dim.3         Dim.4         Dim.5
#> Mlc1      0.0497209920  0.0516028482 -0.0788876048  0.0032493081  6.602336e-02
#> Gprc5b    0.0776530195  0.0767287111 -0.1003795798 -0.0429921843 -6.838634e-02
#> Gfap      0.2737382490  0.2308157480 -0.2703730778 -0.1253583035 -3.101030e-01
#> Ednrb     0.0840708314  0.0699607215 -0.0933344159 -0.0320003544  3.835691e-02
#> Sox9      0.0701589058  0.0648677354 -0.0882498978 -0.0089310657  8.022850e-02
#> Aqp4      0.1648074467  0.1639844662 -0.2047222491 -0.0886550945  3.217967e-02
#> Gjc3      0.0787488199  0.0902074332 -0.0900546455 -0.0683712434 -3.690813e-01
#> Sox8      0.0239282810  0.0501925669 -0.0283113185 -0.0160920618 -1.362323e-01
#> Ntsr2     0.1704425415  0.1601869753 -0.2146941517 -0.0504471528  2.278867e-01
#> Smo       0.0101445414 -0.0602267061 -0.0080775417 -0.0514860143 -8.651041e-05
#> C1qb      0.3469055234 -0.0556488977  0.2697640508  0.0633723690 -4.540910e-03
#> Olig1     0.0649931574  0.0709296076 -0.0604750868 -0.0437817503 -3.264669e-01
#> C1qa      0.3435753209 -0.0679235461  0.2732874719  0.0596583452 -1.168577e-02
#> Pth1r     0.0269966628 -0.0234988709 -0.0578083113  0.0128749364 -5.972937e-02
#> Gabbr2   -0.0968959099  0.0393425389  0.0697732292  0.0299199523 -9.626442e-04
#> Timp4     0.0536090931  0.0280895417 -0.0753163592  0.0158564413  4.382947e-02
#> Abcc9     0.0165480319 -0.0466802006 -0.0509001991  0.0153604110 -1.197030e-01
#> Csf1r     0.2636662717 -0.0386831102  0.2243084956  0.0669753056  9.956118e-03
#> Ntrk2     0.0881426645  0.1012229752 -0.1330898636 -0.0116179071  1.422470e-01
#> Adgrg1    0.0956322507  0.0336898984 -0.0983375842  0.0360269420  8.868170e-02
#> Ntrk3    -0.1084430931  0.0220051827  0.0772323289  0.0089486275 -1.086369e-02
#> Erbb4    -0.0061492024  0.0287309846 -0.0052711701 -0.0106869915 -2.363755e-02
#> Selplg    0.2163849803 -0.0146272024  0.1797440166  0.0711729672 -3.951132e-05
#> Cspg5     0.0508038447  0.1051590276 -0.1171638694 -0.0073861327  1.627924e-01
#> Dlk1      0.0319763185  0.0403762064 -0.0285589767 -0.0211066951 -7.607112e-02
#> Gpr37l1   0.1435865057  0.1348871702 -0.1928914087 -0.0302268679  2.051102e-01
#> Fgfr3     0.0996140210  0.0850286103 -0.1355375615 -0.0118240087  1.574511e-01
#> Slc25a18  0.0698809750  0.0686974956 -0.0947152143 -0.0096511715  1.026733e-01
#> Igf1r    -0.0014116337 -0.0596930778 -0.0528646487  0.0773945525  1.281184e-02
#> S1pr1     0.0822799744  0.0362846623 -0.1354970039  0.0181807874  1.784681e-01
#> Grm5     -0.1118001691  0.0475255721  0.0861476556  0.0347360399 -1.072351e-02
#> Axl       0.0858668222 -0.0487149935 -0.0215858560 -0.0347855205  5.258418e-03
#> Efemp1    0.0261969437 -0.1986612549 -0.0252210424 -0.2406020556  5.172519e-02
#> Adgrb3   -0.0544048314  0.0550664169  0.0217421136  0.0173602267  4.369901e-02
#> Fn1       0.0197391341 -0.3432218159 -0.0678838022 -0.2440058578  5.826913e-02
#> Mertk     0.1227479861  0.0330014625 -0.0359677503  0.0058191331  1.050344e-01
#> Adgrl2    0.0181563638 -0.0994313729 -0.0215071929 -0.0455756732  1.688788e-02
#> Fzd2      0.0166298244 -0.1219469652 -0.0205442251 -0.1621939124  3.165561e-02
#> Aldh1l1   0.0621044803  0.0450324509 -0.0755769710 -0.0463455168  4.455743e-02
#> Adgrg6    0.0049233608 -0.0962329171 -0.0395936687  0.0275253785  1.009561e-02
#> Egfr      0.0095100368 -0.0457057148 -0.0148372962 -0.1032193882  7.474851e-02
#> Kit      -0.0111042732 -0.0886068185  0.0082155796 -0.1106598956 -7.255914e-02
#> Ptgdr     0.0045409154 -0.0885371528  0.0038310671 -0.1341326756  7.176816e-02
#> Gad1     -0.0860206201  0.0439393653  0.0519458282  0.0080321157 -8.142480e-03
#> Tyro3     0.0171943705  0.0416572563 -0.0222654682 -0.0109172887 -1.119973e-01
#> Atp13a5   0.0206112315 -0.1426519762 -0.0496623163 -0.1027289390 -2.015837e-01
#> Ddr2      0.0197099222 -0.1317915730 -0.0023189303 -0.1419593244 -9.013596e-03
#> Rspo3    -0.0315132700 -0.0820764063  0.0224241276 -0.0986280620  4.999107e-02
#> Arhgap29  0.0170582653 -0.1760750472 -0.0446192339 -0.0791462003 -8.717547e-02
#> Fzd7      0.0013466497 -0.0541730858  0.0065291313 -0.0491961687 -3.135484e-02
#> Slc47a1   0.0070042606 -0.2605398556  0.0078046531 -0.4140449341  2.305858e-01
#> Ptger3    0.0028027777 -0.0436933914  0.0017106060 -0.0496212778 -4.140198e-02
#> Bdkrb1    0.0071407966 -0.0148844898 -0.0111734972 -0.0343489894  1.922939e-02
#> Traf4     0.0127022727 -0.0131715780 -0.0050164887 -0.0471016364 -8.346302e-02
#> Cx3cr1    0.2910208672 -0.0295179146  0.2327469236  0.0753681382  2.887251e-02
#> Anxa11   -0.0350383434 -0.0444961512  0.0227879282 -0.0003838839 -8.668919e-03
#> Adgrb1   -0.0912517077  0.0522565195  0.0642316823  0.0288516773 -2.134981e-02
#> Lpar1     0.0309961553 -0.0892477881 -0.0138536553 -0.1042763602 -9.845681e-02
#> Gpr17     0.0210630145  0.0267569595 -0.0347693627 -0.0180771947 -2.030246e-01
#> Cxcl12   -0.0205191339 -0.1197577846 -0.0109975056 -0.0464815062 -3.201204e-02
#> Epha4    -0.0933744058  0.0227970528  0.0629049097  0.0199398111  1.216961e-02
#> Gpr182    0.0217907242 -0.1307174869 -0.0290431428 -0.0359762880 -7.534909e-02
#> P2ry14    0.0061803999 -0.0464150639 -0.0177050305 -0.0297627807 -5.987862e-02
#> Hcar1     0.0112922586 -0.1115686468 -0.0095453473 -0.1018621177 -2.872211e-02
#> Ephb1     0.0142380691  0.0436005945 -0.0301308696 -0.0124731567 -3.450293e-02
#> Grm3      0.0503104535  0.0462853583 -0.0795484416 -0.0249577215 -5.127534e-02
#> P2ry1     0.0082016818 -0.0596404982 -0.0106745751 -0.0548097432 -1.740224e-02
#> Ptk7     -0.0066957877 -0.0125314706  0.0086372160 -0.0162025281 -1.046542e-02
#> Slco1a4   0.0223657930 -0.1657536092 -0.1369393395  0.2191105340 -5.040751e-03
#> Insrr     0.0104466450 -0.0690139103  0.0026752471 -0.0726142014 -8.709213e-02
#> Cmklr1    0.0763628647 -0.0475073233  0.0501998735  0.0350138248 -4.970904e-03
#> Fzd6      0.0192202128 -0.0748877500 -0.0529204409  0.0429010577  7.222569e-03
#> S1pr5     0.0284583918  0.0327079131 -0.0317267539 -0.0271689854 -1.673905e-01
#> Pdgfrb    0.0231063599 -0.0968995924 -0.0605968579 -0.0255074465 -1.062949e-01
#> Flt1      0.0246441573 -0.2259779787 -0.1861946652  0.2724661325 -1.032480e-02
#> Adgrl4    0.0280961325 -0.1382446041 -0.1168323871  0.1888979843  1.109663e-02
#> Lpar6     0.0625796806 -0.0137831249  0.0367979155  0.0174625835  7.205206e-03
#> Epha6    -0.0883902219  0.0310861900  0.0643222427  0.0286811098 -9.171165e-03
#> Emcn      0.0083437378 -0.0598648781 -0.0522568392  0.0706115352 -2.681291e-02
#> Cldn5     0.0311045271 -0.2946074660 -0.2310564448  0.3717678593  1.299561e-02
#> P2ry12    0.2344889997 -0.0116937160  0.1840545925  0.0754388728  2.322359e-02
#> Adgrf5    0.0266564647 -0.1775220011 -0.1348469482  0.2125852103 -9.071991e-03
#> P2yr13    0.1070261760 -0.0040461073  0.0854383239  0.0344185804  7.275986e-03
#> Adgre1    0.1063901755 -0.0230391639  0.0925878260  0.0249118824 -1.363161e-03
#> Cx3cl1   -0.1207742925  0.0391257213  0.0897826344  0.0332051052 -7.772283e-03
#> Plxnb3    0.0465977442  0.0271233361 -0.0068886248 -0.0066219585 -3.097681e-02
#> Flt4      0.0062416946 -0.0660399618 -0.0507326584  0.0868945900  8.260962e-03
#> Slc17a7  -0.1921862304  0.0788625906  0.1402943023  0.0679087015  9.239846e-03
#> Cd300c2   0.1054073418 -0.0143207295  0.0880892016  0.0232454239 -1.552302e-03
#> Tek       0.0133424704 -0.1214264457 -0.0950472703  0.1538389566 -5.129120e-03
#> Kdr       0.0022649406 -0.1017476134 -0.0655678924  0.0854487303 -8.440583e-03
#> Kcnj8     0.0057131652 -0.0600056637 -0.0504989633  0.0313678625 -1.127657e-01
#> S1pr3     0.0090193031 -0.0304064386 -0.0348778543  0.0102899655 -7.646302e-02
#> Tie1      0.0121630145 -0.0911768640 -0.0585413651  0.1039348344 -6.046745e-04
#> Pdgfra    0.0232382302 -0.0434901119 -0.0259810889 -0.0291148512 -1.264767e-01
#> Baiap2   -0.1134937277  0.0312269711  0.0847938141  0.0446083687 -2.995924e-04
#> Calcrl    0.0172670916 -0.0648868288 -0.0450806533  0.0565117118  2.899586e-03
#> Adrb2     0.0565699931 -0.0791478593  0.0446794048 -0.0935164553  3.025000e-02
#> Ccr2      0.0799214988 -0.0207712131  0.0667926120  0.0112386552 -1.135570e-02
#> Alk      -0.0010488678 -0.0386206408 -0.0004323964 -0.0506666242 -7.061478e-02
#> Tacr3    -0.0106678914  0.0043610542  0.0246442035  0.0067405818  9.965484e-04
#> Erbb3     0.0362406240  0.0303559518 -0.0228320219 -0.0204566277 -1.253986e-01
#> Pcdh15    0.0080932950  0.0218323904 -0.0177765291 -0.0113617353 -1.402757e-01
#> Grm7     -0.0892227313  0.0383326484  0.0626967229  0.0281851690 -2.794878e-02
#> F2r       0.0085739763 -0.0195181421 -0.0178674193  0.0234289168 -2.745732e-02
#> Bdkrb2    0.0084295968 -0.0521024891  0.0011408388 -0.0498454028 -5.117463e-02
#> Adgrv1    0.0052015216 -0.0634093489 -0.0061167662 -0.1132172762  7.952108e-02
#> Gprc5c    0.0218727090 -0.0799980468 -0.0023058938 -0.0650826276 -7.341098e-02
#> Tbxa2r    0.0115847334 -0.0363309895 -0.0153433217 -0.0168574532 -7.206869e-02
#> Ackr1    -0.0370746086 -0.0755354129 -0.0157640192  0.1054937156 -6.277259e-03
#> Lpar2     0.0096101481 -0.0183460648  0.0146876147 -0.0096323289 -1.428391e-02
#> Myh11     0.0002481764 -0.0253004153 -0.0093169064  0.0047274734 -1.017785e-02
#> Musk     -0.0062468259 -0.0002631417  0.0015877339 -0.0097866189 -3.799166e-04
#> Cnr1     -0.0381544081  0.0136333966  0.0235657726  0.0089730684  8.090727e-03
#> C3ar1     0.0938388877 -0.0167860039  0.0829960890  0.0252519568 -9.482789e-04
#> S1pr4     0.0084920039 -0.0293263522 -0.0121548940  0.0406779781 -5.382158e-04
#> C5ar1     0.0407262608 -0.0242408168  0.0197387038  0.0060726039  2.093155e-04
#> Fpr1      0.0102649869 -0.0089007948  0.0016960977 -0.0065596254 -6.134903e-03
#> Sctr      0.0120875632  0.0147438127 -0.0194051222 -0.0085722504  2.082209e-02
#> Gpr158   -0.0719496806  0.0266717042  0.0513712092  0.0216498668  2.935536e-03
#> Cxcr4     0.0211939611  0.0230622688 -0.0245363058 -0.0109080198  9.472430e-03
#> Hrh2     -0.0157438030  0.0061802567  0.0113053430  0.0029460645 -1.708804e-03
#> Slc17a6   0.0075493320  0.0126347130 -0.0160556510 -0.0084332711  1.170607e-02
#> Ppp1r3g   0.0149426987  0.0057072636 -0.0289783198  0.0056083236  2.498537e-02
#> Pln       0.0014566290 -0.0267677730 -0.0169765597  0.0225011657  1.028331e-03
#> Grin2b   -0.1116344588  0.0446090148  0.0803789620  0.0382154030  3.556127e-03
#> Taar7e   -0.0084726099  0.0011463210  0.0061755177 -0.0003439554 -1.293362e-03
#> Ptger2   -0.0141897939  0.0058535637  0.0102115853  0.0044346091  2.976632e-03
#> Mc4r     -0.0127097543  0.0043602053  0.0225416940  0.0110976884  3.705846e-03
#> Ghsr     -0.0154668954  0.0060562428  0.0124322219  0.0057590823  3.963661e-03
#> Nmbr     -0.0074165903  0.0065195240  0.0020395102 -0.0012619081  2.023811e-03
#>                  Dim.6         Dim.7         Dim.8         Dim.9        Dim.10
#> Mlc1      0.0182761915  0.0523347399 -0.0032111655  0.0230235230 -0.0565248194
#> Gprc5b   -0.0262843505 -0.0142032221 -0.0142765047 -0.0192770183 -0.1838368268
#> Gfap     -0.1432109312 -0.4711696419  0.1988483486 -0.0869773334  0.2599315051
#> Ednrb     0.0253695787  0.0240351780 -0.0244233651 -0.0168323839  0.0570961610
#> Sox9      0.0194617958  0.0161285816  0.0068747388  0.0009833111 -0.0370000232
#> Aqp4      0.0168151610 -0.2000194904  0.0644950601 -0.1064427544  0.1678385426
#> Gjc3     -0.2249668222  0.0187125465  0.0092513338  0.0300164662 -0.3656457906
#> Sox8     -0.1029165155  0.1565858604 -0.0842068247  0.0378807824  0.0503488863
#> Ntsr2     0.0884161928  0.0601591399 -0.0371910160 -0.0121313690 -0.0967083510
#> Smo       0.0204032629 -0.0058044858 -0.0164654277 -0.0517538708 -0.0178307007
#> C1qb     -0.0045146343  0.0134397160 -0.0040260989 -0.0055953051  0.0022908235
#> Olig1    -0.2183227094  0.2992207978 -0.1164606632  0.0861061922 -0.0153730282
#> C1qa      0.0265435115  0.0352839876 -0.0058782320 -0.0609901020  0.0776634792
#> Pth1r     0.1192601525 -0.0822562649 -0.0551762874  0.1662151256  0.0796146349
#> Gabbr2   -0.0060420466 -0.0368598736  0.0037237541 -0.0011252517  0.0028840412
#> Timp4     0.0221961075  0.0189454104 -0.0167912932  0.0384199346 -0.0328686964
#> Abcc9     0.2182095325 -0.1094258097 -0.1166292107  0.3197324458  0.1021869060
#> Csf1r    -0.0039872866  0.0069499252 -0.0041173345  0.0380562065 -0.0336859045
#> Ntrk2     0.0511733493  0.0717327091 -0.0538904965 -0.0099616986  0.0022584798
#> Adgrg1    0.0025298039  0.0678773694 -0.0206161289  0.0118832364 -0.0138546410
#> Ntrk3    -0.0182734701 -0.0303329643 -0.0569219300 -0.0239051225  0.0257590069
#> Erbb4     0.0337810072  0.1114888125  0.3676286293  0.1321977194  0.0391943206
#> Selplg   -0.0166492391 -0.0325701147  0.0124583651  0.0443160605 -0.0694815595
#> Cspg5     0.0588053237  0.2497969941 -0.0838835292  0.0292717363 -0.0184636223
#> Dlk1     -0.0370457788 -0.1189503512  0.0509739104 -0.0419006607  0.0493256471
#> Gpr37l1   0.0734524486  0.1365465240 -0.0665429465  0.0053271636 -0.0120350632
#> Fgfr3     0.0614918237  0.0683553459 -0.0434531749  0.0043267879 -0.0333005827
#> Slc25a18  0.0460450575  0.0471420472 -0.0256322576  0.0074784083 -0.0294715381
#> Igf1r    -0.0263860700 -0.0048914895  0.0237747562  0.0040855296 -0.0238764256
#> S1pr1     0.0426441384  0.0926183601 -0.0370001534  0.0361212152 -0.0885373515
#> Grm5     -0.0136265137 -0.0253368634 -0.0126006461  0.0083492739  0.0137399997
#> Axl       0.0615630618  0.0589631247 -0.0269283237 -0.1510596057  0.0873346031
#> Efemp1   -0.0977795336 -0.0093346860 -0.0148519474 -0.0732247206  0.0319738411
#> Adgrb3    0.0145943190  0.0249535626 -0.0514289160  0.0065675597 -0.0325743291
#> Fn1      -0.1096320687 -0.0409607248  0.0152232255  0.0225005722 -0.1048090707
#> Mertk     0.0538613613  0.0560714056 -0.0498987058  0.0259874221 -0.0544846829
#> Adgrl2   -0.0366391336  0.0140412802  0.0017077132  0.0088470687  0.0197063658
#> Fzd2      0.0216025019  0.0307080767  0.0038099869 -0.0627489303 -0.0376647634
#> Aldh1l1   0.0394606780 -0.0008650916 -0.0000883376 -0.0235530985 -0.0243189179
#> Adgrg6   -0.0455938014 -0.0190336401  0.0132880950 -0.0100387100  0.0025972170
#> Egfr     -0.0401506692  0.0092118002  0.0368625802  0.0997577331 -0.0045246001
#> Kit       0.1643328179  0.1499310890  0.3135276581 -0.1312016816 -0.0493314123
#> Ptgdr    -0.1020698484 -0.0355963141 -0.0090650888  0.0866547249  0.0186403635
#> Gad1      0.0848189702  0.1838049694  0.6135398399  0.2338461742  0.0557006851
#> Tyro3    -0.0738582593  0.0109487326 -0.0099308167  0.0201310895 -0.1868869758
#> Atp13a5   0.4156398041 -0.0355734050 -0.1188530829  0.1366726192 -0.0923436606
#> Ddr2      0.0040989042  0.0267001405  0.0209132411 -0.0491070756 -0.0262668026
#> Rspo3    -0.0756654554 -0.0391532961 -0.0063675757  0.0419050952 -0.0126148277
#> Arhgap29  0.1372343146  0.0027473224  0.0019229703 -0.0976372311 -0.0599879224
#> Fzd7      0.0661308956  0.0011388257  0.0005691529 -0.0592336654 -0.0302951848
#> Slc47a1  -0.3312521538 -0.0982370651 -0.0191476757  0.3045847111  0.0636210042
#> Ptger3    0.0823116370  0.0008631737 -0.0126837316 -0.0556000006 -0.0561456432
#> Bdkrb1   -0.0110628329  0.0038829796 -0.0126303100 -0.0015596184  0.0385526580
#> Traf4    -0.0808205267  0.2112513817 -0.0882192494  0.0448418656  0.1575704037
#> Cx3cr1   -0.0129814026 -0.0068088011  0.0008859339  0.0592343574 -0.0152954051
#> Anxa11    0.0021707801 -0.0237110949 -0.0335613289 -0.0294535031  0.0110179284
#> Adgrb1   -0.0219547105 -0.0172104134 -0.0214982229 -0.0009003600  0.0378630598
#> Lpar1     0.0783012522  0.0226794982  0.0067210488 -0.1607157529 -0.1337221635
#> Gpr17    -0.1526390784  0.3688384783 -0.1294798463  0.0839906271  0.3339011675
#> Cxcl12    0.0526751453  0.0134351442 -0.0094111965 -0.2086585188  0.0699296202
#> Epha4    -0.0200133275 -0.0480430223 -0.0678625229 -0.0189400851 -0.0229643168
#> Gpr182    0.1079706752  0.0638529181 -0.0076090173 -0.2943283561  0.0600448604
#> P2ry14    0.1220119244 -0.0366363062 -0.0565692745  0.0900498243 -0.0062950824
#> Hcar1     0.0576000275  0.0198625904  0.0091702233 -0.1221614800 -0.0310066152
#> Ephb1    -0.0292070142  0.0004742995 -0.0236911493  0.0113924043 -0.1542648150
#> Grm3      0.0351743531  0.0571313420 -0.0725842424  0.1151556875 -0.1887728158
#> P2ry1     0.0358421937  0.0111424937  0.0177445814 -0.1054133335  0.0425056551
#> Ptk7      0.0260353345 -0.0136236204 -0.0294950704 -0.0679230151  0.0395012941
#> Slco1a4  -0.0961948275  0.0102387245  0.0287978466  0.0077820664  0.0249941964
#> Insrr     0.1781679883  0.0548541029  0.0222958755 -0.1361325513 -0.1062319262
#> Cmklr1    0.0099328492  0.0193009821 -0.0099965038 -0.0915459348  0.0360559183
#> Fzd6      0.0049384870  0.0037551518  0.0119213403 -0.0466852506 -0.0302180426
#> S1pr5    -0.0963220515 -0.0200308654  0.0157231644  0.0152259591 -0.2850641058
#> Pdgfrb    0.2444966016 -0.0199654261 -0.1009689639  0.1049792714  0.0321909308
#> Flt1     -0.0480002049 -0.0339990747  0.0201293447  0.0775369960 -0.0335155759
#> Adgrl4   -0.0540856447 -0.0192198062  0.0214288318  0.0394870638 -0.0123241612
#> Lpar6     0.0152195164 -0.0119031659 -0.0097962263 -0.0018392043 -0.0208473398
#> Epha6     0.0008702446 -0.0431423394 -0.0342848963  0.0084888638 -0.0062207879
#> Emcn      0.0362734114 -0.0132948332 -0.0258691475  0.0708762937  0.0047825581
#> Cldn5    -0.1392357468 -0.0097382495  0.0652331858 -0.0444962737 -0.0120198376
#> P2ry12   -0.0177365118 -0.0370678484  0.0276946109  0.0997067491 -0.0721659528
#> Adgrf5   -0.0413667325 -0.0329967612  0.0198819317  0.0161114927  0.0033448417
#> P2yr13   -0.0082818847 -0.0144377919  0.0084739744  0.0408468585 -0.0348846960
#> Adgre1   -0.0011878222 -0.0045784911  0.0032807719  0.0095419015  0.0322537272
#> Cx3cl1   -0.0107519255 -0.0421281655 -0.0584679024 -0.0313878944  0.0043828950
#> Plxnb3   -0.0229208157 -0.0145414992  0.0206280347  0.0098718099 -0.0151000542
#> Flt4     -0.0407707809 -0.0005811435  0.0145972334 -0.0212555132 -0.0004953907
#> Slc17a7  -0.0242712193 -0.0979783263 -0.1285110480 -0.0386990784 -0.0099813102
#> Cd300c2  -0.0073314833 -0.0059082275 -0.0032696116 -0.0103259388 -0.0118695369
#> Tek      -0.0573345418 -0.0022282707  0.0165178813  0.0087699128  0.0262024416
#> Kdr      -0.0107854074 -0.0025793169  0.0115552863 -0.0180621328 -0.0250915484
#> Kcnj8     0.2045155436 -0.0946506905 -0.1068115750  0.3042285899  0.0935257937
#> S1pr3     0.1386004900 -0.0674970925 -0.0666056885  0.2159729786  0.0750633031
#> Tie1     -0.0548695049 -0.0166445194  0.0189586577  0.0192321890  0.0162260876
#> Pdgfra   -0.0297257338  0.2386784657 -0.0848398924 -0.0967451134  0.2110233808
#> Baiap2   -0.0115012871 -0.0583945948 -0.0714922429 -0.0309682971 -0.0044146994
#> Calcrl   -0.0071179870  0.0524515412 -0.0178244031 -0.0861124287  0.0411015504
#> Adrb2    -0.0332014648 -0.0070854688 -0.0264526840  0.0668783186  0.0975938139
#> Ccr2     -0.0132483753 -0.0013696773 -0.0088841233 -0.0388934439  0.0405884747
#> Alk       0.1114862567  0.1088347245  0.1240958399 -0.0336476065 -0.0480216416
#> Tacr3    -0.0032662136 -0.0164904025 -0.0212280263 -0.0152076821  0.0093712519
#> Erbb3    -0.0755090443 -0.0476671923  0.0253089240  0.0038305963 -0.1736720944
#> Pcdh15   -0.0986505507  0.2108748802 -0.0616036616  0.0582094530  0.0995608816
#> Grm7     -0.0117355616 -0.0472979114 -0.0517445020  0.0052776521 -0.0303220363
#> F2r       0.0025829869  0.0448033026 -0.0441688051  0.0343268188  0.0459188791
#> Bdkrb2    0.0965724175  0.0225397516 -0.0149999178 -0.0513786240  0.0381847660
#> Adgrv1   -0.0956791788 -0.0140641034 -0.0192251505  0.0832828316  0.0196034708
#> Gprc5c    0.1159648986  0.0361277804 -0.0085545908 -0.0805841731  0.0241521925
#> Tbxa2r    0.1332069647 -0.0487187735 -0.0578621117  0.1351736582  0.0983806334
#> Ackr1    -0.0402437814 -0.0218632455 -0.0083402505 -0.0896553691  0.0483979616
#> Lpar2     0.0287285454  0.0132225173  0.0077164653 -0.0818933444 -0.0038463804
#> Myh11    -0.0036734615 -0.0055023409  0.0014547530 -0.0327252066  0.0157818985
#> Musk      0.0231233802  0.0116212710 -0.0012895142 -0.0483731970  0.0115294539
#> Cnr1      0.0505729503  0.0964790514  0.3168813572  0.1196215675  0.0073378777
#> C3ar1     0.0007318926  0.0010301581 -0.0061584228 -0.0135860793  0.0483668571
#> S1pr4    -0.0180446600 -0.0102688902  0.0149532714 -0.0170945729 -0.0196138485
#> C5ar1     0.0186444390  0.0018633778 -0.0030160165 -0.0258686179 -0.0023665300
#> Fpr1      0.0157190855 -0.0105032449  0.0088762163 -0.0436370035  0.0104033105
#> Sctr      0.0105464895 -0.0154293556  0.0079620554 -0.0492531151  0.1157915984
#> Gpr158   -0.0013906665 -0.0285510908  0.0066147622 -0.0063789614  0.0156349912
#> Cxcr4     0.0079715926 -0.0270573006  0.0392406051 -0.0736354782  0.2009611041
#> Hrh2      0.0037567682  0.0042090412  0.0363706629  0.0104729169 -0.0027312019
#> Slc17a6   0.0094554493 -0.0371135225  0.0294658628 -0.0940261543  0.2309738144
#> Ppp1r3g   0.0064060794 -0.0023706537 -0.0041348103 -0.0038533715 -0.0182513720
#> Pln      -0.0079839216  0.0027920698 -0.0001577965 -0.0259833660 -0.0028082592
#> Grin2b   -0.0098278028 -0.0376438960 -0.0441121734  0.0020787405 -0.0057836993
#> Taar7e    0.0018212011 -0.0050037885 -0.0027950221 -0.0293574790  0.0418934633
#> Ptger2   -0.0004158681 -0.0088473544 -0.0103205013 -0.0023845578 -0.0041437677
#> Mc4r     -0.0049557329 -0.0168116324 -0.0257267649 -0.0072906204  0.0015155054
#> Ghsr     -0.0014022151 -0.0115142582 -0.0161237546 -0.0047397372 -0.0017167726
#> Nmbr      0.0155946934  0.0311940862  0.0926225820  0.0275221170  0.0021430226
#>                Dim.11        Dim.12       Dim.13        Dim.14        Dim.15
#> Mlc1     -0.020038499  4.368805e-02  0.017658374  0.0237889875 -0.0014887323
#> Gprc5b   -0.068977469  4.674161e-02 -0.002836844  0.0284616446  0.0248883319
#> Gfap      0.048051535 -2.123727e-01 -0.044360958  0.0176188656 -0.0349386185
#> Ednrb    -0.015601154 -1.024983e-01 -0.015521455 -0.0016168062 -0.0242628718
#> Sox9     -0.022351154 -1.628976e-02  0.022344373  0.0160212396 -0.0068392065
#> Aqp4      0.059265354 -8.562509e-02  0.009188955  0.0018077803 -0.0133083070
#> Gjc3     -0.114414832  1.943950e-01  0.014800378  0.0434896008  0.0195239198
#> Sox8      0.053299106 -4.882687e-02  0.011487680 -0.0189883241 -0.0213036740
#> Ntsr2    -0.001226814 -7.304461e-02 -0.046950518  0.0078976770  0.0190433563
#> Smo       0.054121946 -3.341464e-02 -0.007959094  0.0061000344  0.0509233702
#> C1qb     -0.101234587 -2.376866e-02  0.037292350 -0.0698355400  0.0100176748
#> Olig1     0.019274275  2.066780e-02  0.046628180 -0.0067943529 -0.0130086862
#> C1qa     -0.327690347 -8.079755e-02  0.187035639 -0.0143639919 -0.0764908759
#> Pth1r    -0.033888270  2.302678e-02 -0.067313192  0.0058266081 -0.0035007286
#> Gabbr2    0.002082942 -1.281311e-02  0.004470428  0.0213185548 -0.0088500700
#> Timp4    -0.011867477  3.201045e-02  0.013056866 -0.0017636056  0.0318700042
#> Abcc9    -0.055676500  7.322120e-02 -0.048006826 -0.0971730542 -0.0148455220
#> Csf1r     0.090485252  1.870855e-02 -0.039799256  0.1299624621  0.1228744218
#> Ntrk2    -0.002305177  8.433210e-02  0.077825345 -0.0130551067 -0.0231232906
#> Adgrg1    0.037618933 -8.115803e-03 -0.004499510  0.0239912380 -0.0160994961
#> Ntrk3     0.001613438 -5.524433e-02 -0.026061707  0.0141709575  0.0365869334
#> Erbb4    -0.031161339  3.359559e-03 -0.041391658 -0.0245055347  0.0150867771
#> Selplg    0.360991432  1.350267e-01 -0.225287845 -0.1795895858 -0.2757356520
#> Cspg5     0.008299183  3.079263e-02  0.011680749 -0.0200124690 -0.0131399212
#> Dlk1      0.059565965  6.223031e-03  0.001409311  0.0231149143  0.0268276298
#> Gpr37l1   0.024192425  9.223149e-03  0.015303567 -0.0185641211 -0.0086416711
#> Fgfr3    -0.003980442 -5.142991e-03 -0.021400008  0.0046432699  0.0009511007
#> Slc25a18 -0.035707907  1.989756e-02  0.010314425 -0.0021704947 -0.0054221087
#> Igf1r     0.032290062  6.592975e-02  0.030046617  0.0029889587  0.0690760677
#> S1pr1    -0.025646773  8.776936e-03 -0.016551446 -0.0107987934 -0.0082841000
#> Grm5      0.001272481 -2.842221e-02 -0.019232234  0.0199228111 -0.0132919475
#> Axl      -0.224627641  4.057458e-02 -0.140459983 -0.0431340380 -0.0972244586
#> Efemp1   -0.063983319  1.050285e-01 -0.214728944 -0.0561439709  0.0317470021
#> Adgrb3   -0.007785840 -1.453906e-02 -0.015905161  0.0054159650 -0.0058714403
#> Fn1       0.138224315 -1.450282e-01  0.131583990 -0.3005558461  0.1004061129
#> Mertk     0.057607747  1.264080e-02 -0.011221515  0.0791285694  0.0045157935
#> Adgrl2    0.005448365 -4.522455e-02  0.016707469  0.1167408842  0.0349196891
#> Fzd2      0.021456793 -4.520484e-03 -0.031130641  0.0229075191  0.0411838705
#> Aldh1l1  -0.023774029 -3.310673e-02 -0.008989503 -0.0305344894  0.0121229100
#> Adgrg6   -0.002028408  1.417053e-02 -0.068536134 -0.0802461509 -0.0976092037
#> Egfr     -0.032643563  4.620965e-03  0.012019488  0.0680026874 -0.0385026926
#> Kit       0.062544512 -2.977408e-05  0.041694999  0.1179445218 -0.0477153865
#> Ptgdr    -0.018796432  3.768817e-02 -0.028867877 -0.0162704191 -0.0358041253
#> Gad1     -0.081662277  2.961620e-02 -0.074720040 -0.0425537856  0.0122241666
#> Tyro3    -0.060221733  9.530014e-02  0.017485340  0.0082586590  0.0116224161
#> Atp13a5   0.112565194 -7.938054e-02  0.189537016 -0.0156263922 -0.0443578053
#> Ddr2      0.030475355 -8.566765e-02  0.064196123 -0.0702987777  0.0288278930
#> Rspo3     0.013146570 -2.064306e-02  0.020612609 -0.0389510848 -0.0097748976
#> Arhgap29  0.086391089 -8.757781e-02  0.054522767  0.0140487132 -0.0008055760
#> Fzd7      0.067595298 -1.422837e-02 -0.013572216 -0.0669776365 -0.0656715065
#> Slc47a1  -0.050996249  5.620700e-02  0.012737699  0.1145287300 -0.0825635458
#> Ptger3    0.060555965 -6.480637e-02  0.091237575  0.0322293786 -0.0394575438
#> Bdkrb1   -0.023814487  9.738136e-03 -0.063245451  0.0795604817 -0.0031514369
#> Traf4     0.083523840 -6.639744e-02  0.003518718  0.0001757780 -0.0212051429
#> Cx3cr1    0.053597388 -2.543381e-02  0.040688981  0.0683239127  0.0999276030
#> Anxa11   -0.003010427  2.152018e-02 -0.071228730  0.0077393588 -0.0219749559
#> Adgrb1    0.015425028 -4.084913e-02 -0.003809899  0.0194410205 -0.0032592180
#> Lpar1     0.014754245 -2.576004e-02  0.061073459 -0.0013049857  0.0621189330
#> Gpr17     0.138087162 -1.506092e-01  0.033908953 -0.0329730922 -0.0349453212
#> Cxcl12    0.010472411  1.618876e-01 -0.039533546  0.0813602459  0.0562750941
#> Epha4     0.010078760 -3.572675e-02  0.006354623  0.0003399448  0.0215361453
#> Gpr182   -0.109821109  9.717282e-02 -0.342385852  0.0263718387  0.0780167142
#> P2ry14    0.025744756 -3.130308e-02  0.064018359 -0.0698339489  0.0004043104
#> Hcar1     0.023663773 -1.996512e-02 -0.020023651  0.0115497981 -0.0252107528
#> Ephb1    -0.041200461  8.964523e-02  0.006980214  0.0055263742  0.0093595685
#> Grm3     -0.081837046  1.407191e-01 -0.039754260 -0.0130252228  0.0270471365
#> P2ry1     0.019465520  1.159565e-01 -0.035449554  0.0327524591  0.0232735723
#> Ptk7     -0.054204872  4.565399e-02 -0.093852867  0.0296128220  0.0292700301
#> Slco1a4   0.026249502 -3.491470e-02  0.042919890  0.0730236054 -0.1022275730
#> Insrr     0.095621861 -1.533824e-01  0.204867785  0.1376381615 -0.0902709094
#> Cmklr1   -0.139354247  2.837330e-02 -0.097973780 -0.1828790083  0.1532248356
#> Fzd6      0.019700882 -3.153353e-02  0.060359651  0.0336855298 -0.0473389691
#> S1pr5    -0.099641429  1.650677e-01  0.012417042  0.0160684983  0.0138651449
#> Pdgfrb   -0.038634441  4.812030e-02 -0.085069028  0.0498834091  0.0042292514
#> Flt1      0.032912792 -2.501097e-02  0.104390299  0.0463256622 -0.0241453908
#> Adgrl4    0.006514742 -1.111846e-02  0.037774748  0.1104409943 -0.0438263950
#> Lpar6     0.027827744 -2.145519e-02  0.035808458 -0.0112963829  0.0082153393
#> Epha6    -0.003052361 -3.446541e-02  0.010886529  0.0035294614 -0.0218302935
#> Emcn     -0.016019154  1.716235e-02  0.012921194  0.0353054068  0.0213335308
#> Cldn5    -0.021538240 -2.382138e-02 -0.013384328  0.0471020173  0.0442081829
#> P2ry12    0.386611849  3.758621e-02 -0.150877086  0.1362033992  0.2274988614
#> Adgrf5   -0.028749322 -1.470955e-04  0.021316722  0.0678092908 -0.0358465017
#> P2yr13    0.207066615  2.565520e-02 -0.089833735  0.0422417903  0.0750839493
#> Adgre1   -0.095656927 -1.756532e-02  0.107954947 -0.0227176085 -0.0383590848
#> Cx3cl1    0.021479037 -4.089392e-02  0.013394243  0.0319552624 -0.0267426785
#> Plxnb3    0.065918965 -9.441912e-03 -0.048090419  0.0222511744  0.0355124826
#> Flt4      0.001237470 -2.865386e-03 -0.026920011  0.0194351234 -0.0670762547
#> Slc17a7   0.009820295 -5.657356e-02  0.022882705  0.0289331122 -0.0288857867
#> Cd300c2  -0.124936281  9.072016e-03  0.043270492 -0.1179520783 -0.1136348081
#> Tek      -0.026549529 -6.871399e-03 -0.033318674 -0.0250430705  0.0945011680
#> Kdr       0.052464221 -1.417103e-02  0.073185734 -0.0580878424 -0.0499141067
#> Kcnj8    -0.065786997  9.127713e-02 -0.084275580 -0.0697282946 -0.0022770086
#> S1pr3    -0.051759416  5.563742e-02 -0.059414484 -0.0998813301  0.1009654089
#> Tie1     -0.002356740 -3.315768e-02  0.038728151 -0.0028230776  0.0074174825
#> Pdgfra    0.010513231 -5.051568e-03 -0.138495694  0.0242937847  0.0676010310
#> Baiap2    0.007200391 -2.414732e-02  0.034097473  0.0250554738 -0.0192283730
#> Calcrl   -0.060814149  5.472863e-02 -0.132005341 -0.0018959508 -0.0293391108
#> Adrb2    -0.123244758  2.106492e-02  0.020081861  0.4879664947 -0.0445119354
#> Ccr2     -0.283568784 -1.601459e-02  0.085028130 -0.1841681385 -0.1812689180
#> Alk       0.076684898 -1.207731e-01  0.148315607  0.0466881448 -0.0547710748
#> Tacr3     0.049412737  4.400015e-02  0.009896008  0.0921289200  0.0396572347
#> Erbb3    -0.044241686  9.601851e-02 -0.002442638  0.0032250763 -0.0051474845
#> Pcdh15    0.053854483 -3.008760e-02  0.023461279 -0.0073391578 -0.0196114268
#> Grm7     -0.007287395 -1.344405e-02  0.005035987  0.0023805202 -0.0154317516
#> F2r       0.001451940 -2.096208e-02 -0.010549611 -0.0738825588  0.0958259817
#> Bdkrb2   -0.029166120  9.077230e-02 -0.120356979  0.2531860520 -0.0304536349
#> Adgrv1   -0.009712447  5.085587e-02  0.023711517 -0.0108005355 -0.0247119858
#> Gprc5c   -0.035661611 -3.970576e-03 -0.039994591 -0.0012071195  0.0548320266
#> Tbxa2r   -0.097691236  1.003580e-01 -0.139867799  0.1638783163 -0.0169647743
#> Ackr1    -0.046878595  7.685558e-02 -0.109219154 -0.0541586716 -0.0375944823
#> Lpar2     0.099609394  1.351002e-01 -0.157220735 -0.0437225369 -0.2436105833
#> Myh11    -0.009800230 -2.402366e-02 -0.046643726 -0.2708892012  0.3534617551
#> Musk      0.023765552  6.188543e-02 -0.020671571  0.0881352148  0.0108528417
#> Cnr1     -0.044705047  2.661707e-02 -0.032900404 -0.0432178116  0.0170531212
#> C3ar1    -0.217256238 -6.165339e-02  0.148903746  0.0115011540 -0.0015004071
#> S1pr4     0.122986307  8.022143e-02 -0.082475141 -0.1293823329 -0.3283005053
#> C5ar1    -0.023902383  1.758769e-02  0.043925717 -0.1656464882 -0.3114631520
#> Fpr1      0.124247047  1.377279e-01 -0.062998951 -0.1326442696 -0.2698508684
#> Sctr      0.058895464  2.507629e-01  0.187262382 -0.0276457442  0.0464031290
#> Gpr158    0.010388267  2.916726e-02  0.027324178  0.0135457379 -0.0009297620
#> Cxcr4     0.078613675  3.731709e-01  0.294305974 -0.0264462299  0.0683632093
#> Hrh2     -0.007431172 -2.976020e-03 -0.003014343  0.0056026710  0.0005081364
#> Slc17a6   0.108970045  4.884665e-01  0.363774343 -0.0446393170  0.0800956523
#> Ppp1r3g  -0.009724545 -1.351029e-02 -0.004009719  0.0350344285  0.0006084764
#> Pln      -0.018882124 -2.320328e-02 -0.027951321 -0.2258460285  0.3369657983
#> Grin2b    0.002923810 -2.836359e-02  0.008477210  0.0141848516 -0.0053046041
#> Taar7e    0.032187101  1.041645e-01  0.051049250  0.0559371230  0.0346327649
#> Ptger2   -0.002746009 -7.342839e-03  0.003745769  0.0042079710  0.0007848482
#> Mc4r     -0.012113758 -1.633702e-02  0.029642096  0.0401400378  0.0136978701
#> Ghsr      0.005407458 -1.780903e-02 -0.003365696  0.0051626510 -0.0045798759
#> Nmbr     -0.006712408 -4.749770e-03 -0.006284959  0.0077549790 -0.0082885593
#>                 Dim.16        Dim.17        Dim.18        Dim.19        Dim.20
#> Mlc1     -0.0085195737  0.0454076670  0.1141469728  0.1513094573 -0.0766586895
#> Gprc5b   -0.0500574777 -0.0298408946 -0.0207443142 -0.0103294732  0.0051805356
#> Gfap      0.0216685881 -0.0083902605  0.1127647026  0.0847494263 -0.1004269992
#> Ednrb    -0.0104222666 -0.0317058324 -0.0683060104 -0.0132046955 -0.0030006882
#> Sox9      0.0210271532 -0.0028138266  0.1016544006  0.1087184388 -0.0800062370
#> Aqp4     -0.0170123248  0.0008515506 -0.0907580762 -0.1102144520  0.0660046002
#> Gjc3     -0.0122032831  0.0037671917 -0.0596671988 -0.0384069600  0.0132272069
#> Sox8     -0.0066824876  0.0004354844 -0.0098163567 -0.0109910258  0.0209243325
#> Ntsr2    -0.0112551622 -0.0153751094 -0.1713090778 -0.1075917045  0.1482549542
#> Smo       0.0306897168  0.0219460791  0.0233310357 -0.0136375939  0.0884135721
#> C1qb     -0.0409410741 -0.0511507092  0.0487433495 -0.0211217942  0.0098252555
#> Olig1    -0.0119025347 -0.0019798549 -0.0099140478  0.0033068686  0.0017079799
#> C1qa     -0.0209453769 -0.0218387278 -0.0107061349  0.0245603448 -0.0424701592
#> Pth1r    -0.0347251586 -0.0085555092 -0.0610277157  0.0208458915 -0.0262114002
#> Gabbr2   -0.0154657559  0.0071990985  0.0104283824 -0.0101539791 -0.0209078076
#> Timp4     0.0324223011 -0.0283840251  0.0942773611  0.0487786526 -0.0750493254
#> Abcc9    -0.0389316092 -0.0625035564  0.0385656652  0.0335835478 -0.0523465666
#> Csf1r    -0.0248393156  0.0476564696 -0.0203139565  0.0009389249 -0.0019761272
#> Ntrk2    -0.0159508375  0.0113695354  0.0865325152  0.0968588564 -0.0755840856
#> Adgrg1   -0.0307271364 -0.0147501566 -0.0001438173  0.0147913832 -0.0750199213
#> Ntrk3     0.0384152848  0.0360930244 -0.0191884919 -0.0445150077 -0.0183318294
#> Erbb4    -0.0333265208 -0.0106397540 -0.0338524500 -0.0190270225  0.1184402252
#> Selplg    0.1489658753  0.0036772270  0.0463846756 -0.0732508326  0.0116206437
#> Cspg5    -0.0071345916  0.0596091816  0.1057696857  0.0874017671 -0.0322829174
#> Dlk1     -0.0064684238  0.0330054653 -0.0452406001 -0.0958555918  0.1600062159
#> Gpr37l1  -0.0048062606 -0.0242112009  0.0231265309 -0.0142099244 -0.0106654361
#> Fgfr3    -0.0315245960 -0.0002881528 -0.1252693313 -0.0772715734  0.0847207016
#> Slc25a18 -0.0087766563 -0.0122841616  0.0686878388  0.1072909913 -0.0958635702
#> Igf1r     0.0670524753  0.0349615396  0.1066345624  0.0793229270 -0.0239854144
#> S1pr1     0.0087940692 -0.0021814639 -0.0241949414  0.0217024555 -0.0867462026
#> Grm5      0.0058530966 -0.0588878975 -0.0260135281  0.0112729399  0.0045433718
#> Axl       0.0144491795 -0.0533305361  0.1180891246 -0.0866044244  0.0060023412
#> Efemp1   -0.1698305577 -0.0640437451  0.1243797084  0.0533954899  0.0463348934
#> Adgrb3   -0.0006359178  0.0336053743  0.0031116729 -0.0125861508  0.0634926068
#> Fn1      -0.0765182478  0.0321032722 -0.1279909228  0.2748594327  0.1051273413
#> Mertk     0.0612397009  0.0869306803 -0.0775929957 -0.0607464315  0.1358840897
#> Adgrl2    0.0648811954  0.0754398659 -0.1147039779  0.0723471751 -0.1100928177
#> Fzd2      0.0535511337 -0.0646638993 -0.0060897911  0.0581720171 -0.0296291388
#> Aldh1l1  -0.0103812490 -0.0096530135  0.0042989221 -0.0053076862  0.0380473153
#> Adgrg6   -0.1681465359  0.0804366158 -0.3559356963  0.1330779361 -0.1290750023
#> Egfr      0.0464905737 -0.0305696569 -0.0154221700 -0.1066828423 -0.0808547713
#> Kit       0.0624612115 -0.0486648677  0.0096271870  0.0102961991 -0.3893420909
#> Ptgdr    -0.0369411258 -0.0209260964  0.0177430452 -0.0347500635 -0.0504868547
#> Gad1     -0.0413188454  0.0368202075  0.0369085803  0.0404838547  0.1797804460
#> Tyro3    -0.0128712224  0.0178923762 -0.0158121756 -0.0089876886 -0.0381978325
#> Atp13a5  -0.0794982137 -0.0900595277  0.0579663552 -0.3027185909  0.0691629020
#> Ddr2     -0.0192656947  0.0322949084 -0.0301332691  0.1766780402  0.0829158321
#> Rspo3    -0.0646678479 -0.0416882439 -0.0073931027  0.0109789258  0.0182446502
#> Arhgap29 -0.0217738556  0.0966237051 -0.0282157908  0.1917526928  0.0515756960
#> Fzd7     -0.0060437078  0.0428452705  0.0023495968  0.0354589147  0.0796198080
#> Slc47a1   0.0390428076 -0.0591409839  0.0819137807 -0.2825177989 -0.1198303360
#> Ptger3    0.0081953097  0.0740305784  0.0113457560 -0.0730162432  0.1859162379
#> Bdkrb1   -0.0035743200 -0.0133019427  0.0088635229 -0.0895456974 -0.0239729396
#> Traf4     0.0153475651 -0.0538373869 -0.0102294346  0.0182948930 -0.0006881794
#> Cx3cr1   -0.1152625193 -0.0196091336 -0.0274092428  0.1009393315 -0.0656781984
#> Anxa11    0.0306192051  0.0870956520  0.0036225158  0.0812796929  0.0263027989
#> Adgrb1   -0.0030309554  0.0031840676 -0.0374522760 -0.0153275825  0.0119889861
#> Lpar1     0.0476278263  0.0435928617  0.0020280490  0.0746232367  0.1298102224
#> Gpr17     0.0025401731  0.0005662896 -0.0009479047  0.0123481736  0.0224614597
#> Cxcl12    0.0259587751 -0.0803145670  0.2205790155 -0.0035209260  0.0561066541
#> Epha4     0.0184253750  0.0499462286  0.0336221642 -0.0186218203 -0.0147029244
#> Gpr182   -0.2534755411  0.0179822335  0.0373355099 -0.0495708868  0.0298790012
#> P2ry14   -0.0310073220  0.0288208597 -0.0417865789  0.0630527757  0.1301326691
#> Hcar1    -0.0470973355  0.0150505934  0.0450643238 -0.0254178679  0.0516577090
#> Ephb1     0.0127975795  0.0281064229  0.0253179143  0.0118765408 -0.0003328962
#> Grm3      0.0022015552  0.0155877839 -0.0300991692  0.0250237786  0.0006109857
#> P2ry1     0.0390721615 -0.0938427445  0.0562992587 -0.1027277123 -0.1332649744
#> Ptk7     -0.0409135357  0.0276891219  0.0199729404  0.1202901991  0.0149972077
#> Slco1a4  -0.0094815222 -0.0289233363 -0.1179435583 -0.0949682511 -0.1655249618
#> Insrr     0.0597817209  0.0218277702 -0.0786127688 -0.1992064243 -0.1614080209
#> Cmklr1    0.1632097386  0.0013436902  0.0207133275 -0.1653705027  0.0446512577
#> Fzd6      0.0265825012 -0.0466494382  0.1776002862 -0.0321665848  0.1161788872
#> S1pr5     0.0105981644  0.0057982787 -0.0104436839 -0.0055524275  0.0047167544
#> Pdgfrb   -0.0462453982  0.0160977721 -0.0875000320 -0.0833225399 -0.0444915005
#> Flt1      0.0976784033 -0.0651955465  0.2884047257  0.0587774703  0.1567360944
#> Adgrl4   -0.0719041934  0.0320504003 -0.0174235225  0.1958715886 -0.2212886929
#> Lpar6     0.0369442430  0.0307401746 -0.0111028141 -0.0539153396  0.1667735958
#> Epha6    -0.0328633984  0.0311962798  0.0146187070 -0.0304263515 -0.0399829420
#> Emcn      0.0112364215 -0.0608089652  0.1615072665 -0.0737648102 -0.0399875691
#> Cldn5     0.0204149877 -0.0300858866  0.0162360296 -0.2158661076  0.1110039257
#> P2ry12   -0.1206395661  0.0276429798  0.0376810063 -0.0170559281 -0.0297718489
#> Adgrf5   -0.0179361477 -0.0073426246  0.0599171739  0.0743399481  0.0156419340
#> P2yr13   -0.0498691742 -0.0053933251  0.0438090301 -0.0175744212 -0.0301115745
#> Adgre1   -0.0332917794  0.0027781318 -0.0273154560  0.0623990231 -0.0154906832
#> Cx3cl1   -0.0236891008 -0.0262808304  0.0387385874 -0.0014288352 -0.0200261274
#> Plxnb3    0.0162310820 -0.0063965561 -0.0740935139 -0.0770408568  0.1636894913
#> Flt4     -0.0689538869  0.0311083982 -0.1938909684 -0.0555589375 -0.0894329071
#> Slc17a7  -0.0289146155  0.0425722458  0.0701126970  0.0232735648 -0.0463168975
#> Cd300c2   0.0653548268 -0.0371744124  0.0205018905 -0.0473471820  0.0431594013
#> Tek       0.0428807066  0.0024981139 -0.0606809148 -0.1052841202 -0.0446033273
#> Kdr       0.0369765551  0.0102038582  0.0713548718  0.1320978867  0.1259427385
#> Kcnj8    -0.0791242779 -0.0248090798 -0.0486500116  0.0439075929 -0.0420799390
#> S1pr3     0.0856575460 -0.0040410964  0.0185821025  0.0508504153 -0.0878121111
#> Tie1      0.0573452707  0.0503492062 -0.1206172574  0.0162465182 -0.0191447684
#> Pdgfra   -0.0280317502  0.0103961741  0.0600223309 -0.0192693379  0.0591812252
#> Baiap2   -0.0210210933 -0.0056419399  0.0184234513  0.0248601112  0.0017755543
#> Calcrl   -0.0825650995 -0.0144141564 -0.0286974805 -0.0241529166 -0.0201910941
#> Adrb2     0.3360382142  0.2811331130 -0.1525094350  0.0074651216  0.2421735712
#> Ccr2      0.0584271039 -0.0631775439  0.0210749182 -0.0907168211  0.0473333600
#> Alk      -0.0043677754 -0.0080033500 -0.0526441239 -0.1444832842 -0.1703122653
#> Tacr3     0.1156308656 -0.5966789297 -0.2220151403  0.1309515316  0.1393855384
#> Erbb3     0.0123460118  0.0045883768  0.0145706220 -0.0080291113 -0.0093357840
#> Pcdh15   -0.0091755464 -0.0015889595 -0.0061804856 -0.0125474929  0.0124053132
#> Grm7     -0.0096265761  0.0150826953 -0.0066848793 -0.0249972776 -0.0299233315
#> F2r       0.0719919275 -0.0046989509  0.0245342557 -0.0381912211 -0.0784106718
#> Bdkrb2    0.2010754130  0.0474197417 -0.0581638144  0.1524579982 -0.0697287089
#> Adgrv1   -0.0160691881  0.0132584677  0.0307908039 -0.0093861950 -0.0214274700
#> Gprc5c    0.0740692169  0.0287902200 -0.0017672519  0.0517832804 -0.1127999995
#> Tbxa2r    0.1305016941  0.1503861452 -0.0737853764  0.1974737247  0.0954673505
#> Ackr1    -0.2657185417  0.0858147840 -0.3763377642 -0.1389111711  0.0075835804
#> Lpar2     0.1990541333 -0.0250342554  0.0278117992  0.0038384971 -0.0739159649
#> Myh11     0.3649418131  0.0889725133 -0.1321931539 -0.0430186219 -0.1498945525
#> Musk      0.1214191217 -0.4011116559 -0.1282297031  0.0941054269  0.0118160945
#> Cnr1     -0.0047298496 -0.0408812466 -0.0349508124 -0.0361086685  0.0486008767
#> C3ar1    -0.0117289562  0.0058619154 -0.0525103081  0.1120648053 -0.0385012289
#> S1pr4     0.1511210992  0.0484036098 -0.0919908814  0.0087802323 -0.0217401247
#> C5ar1     0.1443211662  0.0300653021 -0.0607538893  0.0750615740  0.0418080878
#> Fpr1      0.1421456315  0.0744722958 -0.0184353173  0.0521160088  0.0255547151
#> Sctr     -0.0330887728  0.0666106592 -0.0063804028 -0.0209689294  0.0298516721
#> Gpr158   -0.0023256167 -0.0625109056 -0.0336775163  0.0016981989  0.0051665279
#> Cxcr4    -0.0575271503  0.0787331352 -0.0303409285 -0.0114721046  0.0176789925
#> Hrh2      0.0005356513 -0.0148151194 -0.0057769739 -0.0029742509 -0.0092350390
#> Slc17a6  -0.0637812076  0.0811486979 -0.0520220567 -0.0420846588 -0.0016604208
#> Ppp1r3g   0.0174926413 -0.0332248554  0.0471978865  0.0042481764 -0.0125994109
#> Pln       0.3576715486  0.0543837430 -0.0668504524 -0.0935214247 -0.0945407711
#> Grin2b   -0.0037063454 -0.0072530994  0.0167725707  0.0079731903 -0.0081018447
#> Taar7e    0.0737504560 -0.3898461040 -0.1448294465  0.0772201013  0.0581309367
#> Ptger2   -0.0021096567 -0.0010385808 -0.0005894454  0.0127397014 -0.0048440244
#> Mc4r      0.0076238585 -0.1138043516 -0.0467649405  0.0685592598  0.0376308817
#> Ghsr     -0.0106874954  0.0422288348 -0.0115748420 -0.0062335690  0.0068787700
#> Nmbr      0.0034666140  0.0063363502  0.0274438556  0.0325759907 -0.0578854141
#>                 Dim.21        Dim.22        Dim.23        Dim.24       Dim.25
#> Mlc1      0.1915296127 -0.0775793281  1.188980e-01 -0.1047555231  0.039556093
#> Gprc5b   -0.0549817793  0.1054921539  7.393436e-02  0.0955792131 -0.013942117
#> Gfap      0.1922578511 -0.0645327114 -2.621349e-02 -0.0186868143  0.009780146
#> Ednrb    -0.0857139129  0.0753131208  6.767365e-02  0.1590247489 -0.027178242
#> Sox9      0.1795569333 -0.0475052367  4.654244e-02  0.0929118497  0.120863030
#> Aqp4     -0.1309970473  0.0693509209 -2.816152e-02 -0.0218622199 -0.068119575
#> Gjc3     -0.0646711374  0.0237506169  1.489202e-02  0.0248995659 -0.032100665
#> Sox8     -0.0693108081  0.0380768110  1.209124e-02  0.0080231226  0.004328523
#> Ntsr2    -0.3150781218  0.1608868117  2.892064e-02  0.0202361416 -0.074566497
#> Smo       0.0008163573  0.0220998235 -6.797454e-02 -0.0275337637 -0.006732909
#> C1qb     -0.0378975712  0.0022957083 -4.423654e-02 -0.0714302646 -0.035476834
#> Olig1    -0.0067851126  0.0669816723  3.649786e-02  0.0696325488 -0.032918211
#> C1qa     -0.0451707731  0.0255322639  7.364687e-03  0.1398990887  0.142937254
#> Pth1r    -0.1351896289 -0.0296428715 -4.989838e-03 -0.0501482100 -0.032546374
#> Gabbr2   -0.0269917135  0.0391783687 -3.499100e-03 -0.0081500785  0.002617412
#> Timp4    -0.0070541938 -0.0156677502  1.124549e-01  0.0377080530  0.042622457
#> Abcc9    -0.0196602900 -0.0014578050 -8.203687e-02  0.0599900089 -0.057177330
#> Csf1r     0.0310847863  0.0028615381 -5.470127e-03 -0.0234037359 -0.024221078
#> Ntrk2     0.1637291832 -0.0524484108 -3.886686e-02  0.0269026249  0.036738491
#> Adgrg1   -0.0071002039  0.0661790729  5.533680e-02 -0.0285386371  0.064969723
#> Ntrk3    -0.0894624038 -0.0293185716  6.636749e-02  0.0478123480  0.028125640
#> Erbb4    -0.0438301823  0.0505355260  6.982946e-02 -0.0051399622  0.011977923
#> Selplg   -0.0237587787 -0.1423122359  5.340832e-03  0.0240740011  0.053734175
#> Cspg5     0.2482102708 -0.1022354809 -1.241259e-01 -0.0929838030 -0.039540781
#> Dlk1     -0.1502080544 -0.0853319880 -8.517056e-02 -0.2127173934  0.041595810
#> Gpr37l1   0.0135719057  0.0291321546 -3.525957e-02  0.0001086977 -0.013996373
#> Fgfr3    -0.1721850307  0.0678645918 -1.516023e-02  0.0394986280 -0.059449655
#> Slc25a18  0.1097588989  0.0139540116  4.739821e-02  0.1313221098  0.071763583
#> Igf1r    -0.1319286762 -0.0155879648  1.086816e-01 -0.0845456483  0.049837506
#> S1pr1     0.0775983241 -0.0212825731 -1.812987e-02 -0.0295971476 -0.072389663
#> Grm5     -0.0578682216  0.0065440157  4.607397e-02 -0.0570421491  0.050593352
#> Axl      -0.0421322918 -0.2090089904 -1.189651e-02 -0.2001379200  0.101831406
#> Efemp1   -0.0308067445  0.0907488932 -2.116584e-03 -0.0754105592  0.021921933
#> Adgrb3   -0.0361829194 -0.0403740166 -2.195078e-02 -0.1325377403  0.076290144
#> Fn1      -0.0130333973  0.0418717859 -1.778008e-01 -0.0778997286  0.182133989
#> Mertk    -0.0065795361 -0.1505777324 -7.066423e-02 -0.2346000054  0.059578124
#> Adgrl2   -0.2394445015 -0.3259797433  6.379235e-02 -0.0258658395 -0.034654336
#> Fzd2     -0.0599796230 -0.0275748427 -2.405904e-02  0.0472897658  0.023335048
#> Aldh1l1   0.0292838084  0.0370187498  2.924074e-02  0.0246408159  0.019462586
#> Adgrg6    0.0655004840 -0.0256342471  2.808014e-02 -0.0639609223  0.006761307
#> Egfr     -0.0245010706 -0.0394974471  1.304427e-02  0.0507365135 -0.052561221
#> Kit      -0.1302903743  0.0561945445 -3.042602e-01 -0.1074716049 -0.116328470
#> Ptgdr     0.0475336332  0.0729000814  1.396272e-02 -0.0096917636 -0.017308596
#> Gad1      0.0351630056  0.0631986508  1.529795e-01 -0.0705984997  0.083019020
#> Tyro3    -0.0082839583  0.0191431291  4.284894e-03  0.0744030060 -0.019025913
#> Atp13a5   0.1680743403  0.1364207264  8.035783e-02 -0.0519511047  0.096049593
#> Ddr2     -0.0890726112 -0.0377890556 -5.113698e-02 -0.0178983854  0.012928557
#> Rspo3     0.0427108983  0.0620073040 -8.238892e-02 -0.0207517572 -0.005663147
#> Arhgap29 -0.0759247189 -0.1634788782  1.487002e-01  0.0215307366 -0.077727202
#> Fzd7     -0.0049434314  0.0478681321  3.197551e-02  0.0300620233  0.040444167
#> Slc47a1   0.0278350596 -0.0189630903  1.203786e-01  0.0805415257 -0.100325586
#> Ptger3    0.1821198247  0.0940800936  3.031294e-01 -0.0568593610 -0.171691783
#> Bdkrb1   -0.1705963809 -0.1837312611  1.690605e-01  0.1422144193 -0.029735535
#> Traf4    -0.0652595237 -0.1566988300  7.713567e-03  0.0098088611  0.003184511
#> Cx3cr1   -0.0523244863  0.1614972308  3.348895e-02  0.1108636180 -0.038719249
#> Anxa11    0.0235100249  0.1610749464  7.062493e-02 -0.1370160976 -0.152779570
#> Adgrb1   -0.1035804454  0.0239864016  2.194852e-02 -0.0111045282  0.010375879
#> Lpar1     0.0148901669  0.0871035222  5.238635e-02  0.0210393210  0.047568830
#> Gpr17     0.0142770197  0.0502802828 -1.561353e-02 -0.0838472507  0.025720278
#> Cxcl12   -0.0447495610  0.1839532946  4.570104e-02 -0.0229134805 -0.190689409
#> Epha4     0.0029347634  0.0520147048 -1.720780e-02 -0.0361172921  0.006550585
#> Gpr182    0.0330825785 -0.1028483534  1.811424e-01  0.1358389851  0.100979884
#> P2ry14    0.0274296820  0.0409666039  6.252702e-02 -0.0204289854 -0.126415668
#> Hcar1     0.0915852497 -0.0061217078  4.702383e-02  0.0388286949  0.007418826
#> Ephb1     0.0760060150 -0.0925606793 -3.482857e-02 -0.0854802709  0.068879785
#> Grm3     -0.0294356800 -0.0161372792 -1.016288e-01 -0.0571748475 -0.019593065
#> P2ry1     0.0658796707  0.2103749965 -5.493685e-02 -0.0613315566 -0.134045773
#> Ptk7     -0.1271409629  0.0022200278  6.260802e-02  0.0514920068  0.067134756
#> Slco1a4  -0.0581462781  0.2473115570  4.038462e-02 -0.1752912882  0.326081914
#> Insrr     0.0722906354 -0.1653379254  4.408181e-02  0.0576055048  0.053452613
#> Cmklr1    0.0816103928 -0.0748592653  7.695998e-03 -0.0870568740 -0.019758231
#> Fzd6      0.0061848117  0.0564681906 -8.512828e-02  0.0921004446  0.264314420
#> S1pr5    -0.0055743413 -0.0384014178 -1.825326e-02 -0.0331679302  0.009633422
#> Pdgfrb   -0.0473592278 -0.1456486559  1.494873e-02  0.0356618717 -0.027092292
#> Flt1     -0.1026684893 -0.0714492371 -1.135830e-01  0.1238304260 -0.196860521
#> Adgrl4   -0.0177759841 -0.0347506282  4.085207e-01 -0.2671020435 -0.164510243
#> Lpar6     0.1151728438  0.0633872370  9.056173e-02 -0.2518560138 -0.224137363
#> Epha6    -0.0517991009  0.0363953001 -1.383327e-02  0.0205771055 -0.014042106
#> Emcn     -0.0723361689  0.0307737319  1.605557e-01 -0.0804214354  0.112265716
#> Cldn5     0.0643915183  0.0570685391 -1.963390e-01  0.1222492732  0.093313284
#> P2ry12    0.0718742339 -0.0080271530 -1.016152e-02 -0.0225860937 -0.051489517
#> Adgrf5   -0.0604241979 -0.0071129981  4.124845e-02  0.0288662522  0.080089978
#> P2yr13    0.0103589697 -0.0666281028 -3.599000e-02  0.0737256473  0.074483339
#> Adgre1    0.0169277476  0.0940930525 -5.044943e-03  0.0160999981 -0.056368849
#> Cx3cl1    0.0282788378  0.0380254676 -2.730562e-02 -0.0428136299 -0.049911542
#> Plxnb3   -0.1039976175 -0.0452809544 -3.335290e-02 -0.1533483006  0.007199098
#> Flt4      0.0842881314  0.0794349639  5.076787e-02 -0.0713730767  0.022184847
#> Slc17a7   0.0529870744  0.0309162783 -8.536686e-02  0.0009543436 -0.054296954
#> Cd300c2  -0.0022153209 -0.0652456431 -4.496447e-02 -0.1782036297 -0.026796807
#> Tek       0.0349380048 -0.1041160462  9.621805e-03 -0.0632201723 -0.187130120
#> Kdr      -0.0001065728 -0.1522020960 -5.818851e-02  0.1216971770 -0.238345695
#> Kcnj8    -0.0373977761  0.0007711152 -7.692070e-02  0.0047830671 -0.014409797
#> S1pr3    -0.0179942689  0.0141945645  5.989462e-03 -0.0073935241  0.027838346
#> Tie1      0.0490415738 -0.0221670333 -6.525411e-02  0.0408185329 -0.190912656
#> Pdgfra    0.0568424442  0.0135379883 -2.578229e-02  0.0953814973 -0.094924247
#> Baiap2   -0.0229886967 -0.0334974481  8.064383e-05  0.0166931309  0.023302140
#> Calcrl    0.0146759878 -0.0506724135  1.157563e-02 -0.0664675326  0.015409180
#> Adrb2     0.1702886789 -0.0187340267  1.710123e-02  0.0419787429  0.106784215
#> Ccr2     -0.0163637115 -0.0921578924 -5.424001e-02 -0.1957791164 -0.059604232
#> Alk      -0.0091945410 -0.1207342981 -1.613326e-02  0.0259093232  0.015274026
#> Tacr3     0.1166453990 -0.1094358701  9.404744e-02 -0.0297390133  0.065286282
#> Erbb3     0.0504126446 -0.0813916892 -2.597030e-02 -0.0519744464  0.029246012
#> Pcdh15   -0.0137964915  0.0069633706  5.482266e-03 -0.0390587648  0.005226138
#> Grm7     -0.0789824401 -0.0387842261  3.279386e-02 -0.0034453666  0.054725745
#> F2r       0.0002731697  0.0850207656  6.741221e-02 -0.0681855080  0.122440116
#> Bdkrb2   -0.0293343803  0.1707003683 -2.598696e-01 -0.0629872847 -0.057508695
#> Adgrv1    0.0776992061 -0.0166361826 -3.535026e-02 -0.0723248882  0.068710615
#> Gprc5c   -0.0603997950 -0.0022632305 -5.038082e-02  0.0151884955 -0.014245735
#> Tbxa2r    0.0441911551  0.0700651325 -8.228275e-02  0.0202017055  0.154505812
#> Ackr1     0.2846627471 -0.0262780963 -1.053864e-01  0.1223092467 -0.094425835
#> Lpar2    -0.0299119081  0.1651707475  2.160898e-03 -0.0478955122 -0.083232676
#> Myh11     0.0548558494  0.0488557813  1.186295e-01  0.0534110707  0.027524435
#> Musk      0.0487086457  0.0284900644 -2.977132e-03 -0.0276613413 -0.027360978
#> Cnr1      0.0812875540 -0.1086635698 -8.253053e-02  0.2155287355 -0.120389805
#> C3ar1     0.0014665066  0.1555176354  7.966131e-02  0.0598280122 -0.130643545
#> S1pr4     0.0074997616  0.1078870436  8.636952e-02  0.0984612487  0.100035616
#> C5ar1    -0.0107388057 -0.0243464893  2.381740e-02  0.1464612196 -0.122396115
#> Fpr1     -0.0194940999  0.0407137532  1.569073e-01  0.1197729073  0.046365118
#> Sctr     -0.0498048556 -0.0484184472  6.695343e-03 -0.0508495242  0.055967438
#> Gpr158   -0.0306629755 -0.0284880958  3.781557e-03  0.0290347186  0.025185048
#> Cxcr4    -0.0208451388 -0.0238596036  1.731148e-02  0.0177518523  0.043120715
#> Hrh2     -0.0392549625  0.0034152926  9.768157e-03  0.0272326808  0.006284775
#> Slc17a6  -0.0685068391 -0.0232995367  7.812815e-03  0.0252356233  0.019338479
#> Ppp1r3g  -0.1146618589  0.0481419552  9.165347e-02  0.1199346583  0.067176668
#> Pln       0.0377710810  0.0214811455  9.177542e-02  0.0642456846  0.015404950
#> Grin2b   -0.0189247989 -0.0240678424  3.032638e-02 -0.0284279563  0.028220773
#> Taar7e    0.0746391677 -0.0467185618  4.526955e-02 -0.0025209992 -0.011327564
#> Ptger2   -0.0513065600 -0.0282519419 -2.183082e-03  0.0283308709  0.054729800
#> Mc4r      0.0040838607  0.0148713775  2.407896e-02  0.0473205192  0.062254269
#> Ghsr     -0.0429698126  0.0905348676 -7.673134e-03 -0.0353486070 -0.084151681
#> Nmbr      0.0007378491  0.0167915444  4.181913e-02 -0.1192725539  0.039587431
#>                 Dim.26       Dim.27       Dim.28        Dim.29        Dim.30
#> Mlc1      0.0878326009 -0.031554386 -0.052232152  0.0609383219 -4.327478e-02
#> Gprc5b    0.0266762043 -0.039531707 -0.049043569  0.1104838027 -6.467555e-02
#> Gfap     -0.0494719092 -0.017458645 -0.043128027  0.0081429937 -8.251075e-05
#> Ednrb    -0.0530457336 -0.148733210  0.065974757  0.0499350757  3.389917e-02
#> Sox9     -0.0672063613 -0.162932025  0.051151747 -0.1020523191  3.874905e-01
#> Aqp4      0.0592358591  0.030184146 -0.028689560  0.0506476477 -2.481883e-01
#> Gjc3      0.0357945574  0.003202220 -0.006444576  0.0485987561 -8.312943e-02
#> Sox8     -0.0188897330 -0.078855629  0.092491484 -0.0559746829  9.558878e-02
#> Ntsr2     0.0504637656 -0.176450341  0.055451770  0.0134966856  3.486750e-02
#> Smo       0.0453936042  0.023671510 -0.065132998 -0.2113907017 -4.484915e-02
#> C1qb     -0.0215946649 -0.101322647  0.085774897 -0.0819027638 -8.131109e-02
#> Olig1     0.0247423562 -0.085746692  0.076348594  0.0527235675 -3.159326e-02
#> C1qa      0.0590101044  0.032300526  0.020531352  0.0658019746  6.004304e-02
#> Pth1r     0.0793276583 -0.005238304  0.001428507  0.0212095978 -3.044433e-02
#> Gabbr2   -0.0305160056 -0.118445617 -0.067985257  0.0499118246  3.474506e-02
#> Timp4    -0.0493329144 -0.041776903  0.153002613 -0.0330770783  1.500863e-01
#> Abcc9    -0.0757869797  0.037515666 -0.055190640  0.0064512197  5.241319e-02
#> Csf1r    -0.0131894640  0.000217194 -0.077239650  0.1476638797 -4.309852e-02
#> Ntrk2     0.0163004913  0.055111531 -0.074643734 -0.0237210294 -7.040035e-02
#> Adgrg1   -0.0058308493  0.016603641  0.026238851 -0.0101407289 -2.807227e-02
#> Ntrk3     0.0943404860 -0.019256972  0.042941248 -0.0488731366  7.731345e-04
#> Erbb4    -0.0064517986 -0.010028324 -0.008534764  0.0249517081  4.463517e-02
#> Selplg   -0.0062924933 -0.075122971  0.056811882  0.0051738475 -2.786504e-02
#> Cspg5     0.0857373544  0.138007454 -0.148216221 -0.0310079249 -1.113713e-01
#> Dlk1      0.1781898410  0.314953528 -0.054369871 -0.0981283513  2.856689e-01
#> Gpr37l1  -0.0360816617  0.105188454  0.041953590  0.0340459382 -1.103544e-01
#> Fgfr3     0.0168849115 -0.054696630  0.010630278 -0.0264946717  5.159248e-02
#> Slc25a18 -0.0407008927 -0.066576135  0.063476504 -0.0941031416  1.169619e-01
#> Igf1r     0.0989874486  0.031592682  0.034262069 -0.0011935919 -6.570448e-02
#> S1pr1    -0.0067576752 -0.035319043  0.003840092  0.0147899280  1.971587e-02
#> Grm5      0.0668234244 -0.136042051 -0.100133227  0.0216725130  1.294152e-03
#> Axl      -0.1348052408 -0.124081403  0.168227653  0.0894831268 -6.117716e-02
#> Efemp1   -0.0152696437  0.045425742  0.004004264  0.2139556479  2.870743e-02
#> Adgrb3    0.0388614971  0.051592324 -0.149109419 -0.0429966570  3.560675e-03
#> Fn1       0.0335436994 -0.082264286  0.039691909  0.1343236923 -7.331423e-02
#> Mertk    -0.0369605346  0.115825408 -0.079525691  0.0823553238  1.518291e-01
#> Adgrl2   -0.3031091437  0.028781274 -0.207955907  0.0745953458 -6.911698e-02
#> Fzd2     -0.0196474015  0.018704715 -0.023720686 -0.0322295596 -3.000988e-02
#> Aldh1l1  -0.0263065087 -0.060703639 -0.018103907 -0.0417042691  1.716239e-01
#> Adgrg6    0.0361455668  0.003214755  0.047600691  0.0045602572  1.369179e-01
#> Egfr      0.0280105881 -0.011982193  0.016522429  0.0212010703  7.916745e-02
#> Kit       0.0972844998 -0.092067037 -0.034762412 -0.1832517095 -4.940600e-03
#> Ptgdr     0.1345251674 -0.000972766  0.051564822 -0.1181973448  7.937212e-03
#> Gad1      0.0024803734 -0.194092523 -0.192166030  0.0670521660  1.304732e-02
#> Tyro3    -0.0493684085 -0.050504987  0.023277967  0.0372930755 -1.383876e-01
#> Atp13a5   0.1102318274  0.024697697  0.009097302  0.2381686049  3.128646e-02
#> Ddr2     -0.1446549432 -0.027029968  0.068535023  0.1285995983  5.105404e-02
#> Rspo3     0.0383895382 -0.035471854  0.031994932 -0.0143180908  3.120201e-02
#> Arhgap29 -0.1331337804  0.019387670 -0.037186917 -0.0970775070 -1.215439e-02
#> Fzd7     -0.0528645423 -0.011210582 -0.099259268 -0.1107655688 -5.502641e-02
#> Slc47a1   0.0685560012  0.004504328 -0.049894809 -0.1428134117  1.662631e-02
#> Ptger3   -0.1149578447 -0.042873330  0.106208116 -0.3370559455 -9.293049e-02
#> Bdkrb1   -0.1680616312 -0.011605796 -0.161110710 -0.0197742199 -1.050297e-01
#> Traf4    -0.0630089584 -0.027047711 -0.017562959 -0.0463541917 -9.093199e-03
#> Cx3cr1    0.0366827055  0.108030351 -0.128763735 -0.0418743908  2.729474e-02
#> Anxa11   -0.0863467963 -0.041412179  0.061795794 -0.0759335373  4.787142e-02
#> Adgrb1    0.0549825835 -0.008844257  0.051408140 -0.0631193365  4.643709e-02
#> Lpar1     0.0137152954  0.055999299  0.061006148  0.0858385591  2.524876e-04
#> Gpr17    -0.0223114865  0.018027367  0.030622844 -0.0183894958  6.041809e-02
#> Cxcl12   -0.2963198493  0.043134523 -0.119446216  0.0622156948  1.554433e-01
#> Epha4     0.0111556311  0.027688422  0.003784837  0.0138894000 -6.321837e-03
#> Gpr182    0.2007643471  0.035824747 -0.036956261 -0.0773790951 -7.640493e-02
#> P2ry14   -0.2364683506 -0.019830170  0.038821070 -0.1339712090 -5.014946e-02
#> Hcar1     0.1225357064 -0.041110950  0.050346020 -0.1285632251 -4.310207e-02
#> Ephb1    -0.0236999760  0.021289044 -0.054030447 -0.0610688352  5.894711e-02
#> Grm3     -0.0782805813  0.086986043 -0.129667389 -0.0813163748 -6.732860e-02
#> P2ry1    -0.0511806935  0.045476010 -0.002367790  0.1490886369  1.694638e-01
#> Ptk7      0.0798616091  0.070500912  0.026882353 -0.1466074254  9.984724e-02
#> Slco1a4  -0.2864905757  0.101842785 -0.010535223 -0.0650067902 -6.822307e-02
#> Insrr     0.0601051358 -0.035821179  0.025679008  0.0488050424  5.633710e-02
#> Cmklr1    0.0107302382 -0.085659926  0.006279165 -0.0012097785 -1.436438e-02
#> Fzd6     -0.1425180046  0.061246515 -0.147816959 -0.1041921465 -2.410132e-02
#> S1pr5    -0.0506516216  0.017536520 -0.044307381 -0.0790472463  9.719188e-02
#> Pdgfrb    0.0125975243 -0.051232736 -0.086742556 -0.0484353510 -2.149450e-03
#> Flt1      0.1653240781 -0.075068582 -0.050347023  0.0651332978  1.794405e-02
#> Adgrl4    0.1435699479  0.078051246  0.158031934  0.0742145348 -1.074896e-03
#> Lpar6    -0.0222805323 -0.012269824 -0.008655777 -0.0573717230 -5.333696e-02
#> Epha6     0.0159374398 -0.032846947  0.072974666  0.0203934005 -1.367737e-02
#> Emcn      0.0952552735  0.040602359  0.097512203  0.1253907961  2.392048e-03
#> Cldn5     0.0082470676 -0.060041113 -0.053222653 -0.1486896343 -9.740433e-02
#> P2ry12   -0.0337505895 -0.064679455  0.033735272 -0.0276427592 -2.588625e-02
#> Adgrf5    0.0375343520  0.031342987  0.084864311 -0.0314227372  9.929285e-02
#> P2yr13   -0.0363893658 -0.079012939  0.090692759 -0.0009564144  3.512341e-02
#> Adgre1    0.0201581756  0.114743529 -0.058297038 -0.0811050654  3.813620e-02
#> Cx3cl1   -0.0533999581 -0.045979008 -0.044004851  0.0333713394 -8.758802e-03
#> Plxnb3    0.1341216837  0.171633978 -0.001815338 -0.1323667363  3.091820e-01
#> Flt4     -0.0561713369  0.015003327 -0.030172469 -0.0689513385 -6.067844e-02
#> Slc17a7  -0.1062673986 -0.029563099 -0.042975586  0.0216234961 -1.287816e-02
#> Cd300c2  -0.0379306242 -0.069730519  0.031819664 -0.1032123642  7.221290e-02
#> Tek       0.0483088968 -0.064006036  0.048860425  0.0906851316 -3.534582e-02
#> Kdr       0.0440265375 -0.062007461  0.004704177  0.0951282602  1.219989e-01
#> Kcnj8    -0.0753363763 -0.002278412 -0.070268701 -0.0531139703  3.043310e-02
#> S1pr3    -0.0288632831 -0.006001427 -0.021149635 -0.0336954404 -1.976000e-03
#> Tie1      0.0593750107 -0.066463298 -0.054573535  0.0039347637  1.054054e-02
#> Pdgfra    0.0966501397  0.072571474 -0.127076991  0.0151140353  1.331437e-02
#> Baiap2    0.0430865137 -0.068162152 -0.022952534  0.0028469305  3.222641e-02
#> Calcrl   -0.0183297629  0.032420069 -0.003017751  0.1557521916  6.885191e-02
#> Adrb2    -0.0497672651 -0.022470164  0.013146006  0.1804478675  1.209893e-02
#> Ccr2     -0.0538249124 -0.112410077  0.100603060 -0.0738814919 -8.365261e-02
#> Alk       0.0571780616  0.015428745 -0.001127190  0.0187479256  3.411386e-02
#> Tacr3     0.0581946328 -0.023971821 -0.076696685 -0.0818014747 -6.075309e-02
#> Erbb3    -0.0370666800 -0.006967861 -0.014557870 -0.0804474115  1.351229e-01
#> Pcdh15    0.0355974063 -0.032915103 -0.030134878 -0.0367493327  1.059245e-02
#> Grm7      0.0947724949  0.019858967  0.086543510  0.0362762156 -1.441902e-02
#> F2r      -0.0593552348  0.099757387 -0.041277910  0.0043312184  7.406235e-03
#> Bdkrb2    0.0414940104 -0.075858743  0.147780599 -0.0054418456 -3.582223e-02
#> Adgrv1    0.0349501476  0.018624239  0.002272959 -0.0354309548 -2.592842e-02
#> Gprc5c    0.0410839680  0.016269325 -0.026757826 -0.2465729600 -4.951070e-02
#> Tbxa2r    0.1527418870 -0.124352484  0.194509097 -0.1089740480 -9.541720e-02
#> Ackr1    -0.0717578364 -0.109322320 -0.057032195  0.0508922219  1.486985e-01
#> Lpar2    -0.0280515870  0.059642931 -0.037260877  0.1649670014  4.967281e-02
#> Myh11     0.0063646923  0.048941311 -0.050283091  0.0200373312  3.512964e-02
#> Musk     -0.0045792218  0.008050093  0.069816603  0.0292692270 -1.254557e-02
#> Cnr1     -0.1830336117  0.475317766  0.420329340 -0.0044069128 -8.615662e-02
#> C3ar1     0.0813728777  0.198159289 -0.255695077  0.0009797477 -1.036759e-02
#> S1pr4    -0.0203591492  0.096305901 -0.133002377 -0.0003491943 -2.967056e-02
#> C5ar1     0.1262845220  0.056913353 -0.109911244  0.0759594366  1.227053e-01
#> Fpr1      0.1051174552  0.054466506 -0.034666716 -0.0538367837 -9.876932e-02
#> Sctr      0.0298647435  0.013300436  0.027415609 -0.0095308161 -6.271336e-02
#> Gpr158    0.0027107531  0.011647145  0.087454663  0.0338829917 -7.746748e-03
#> Cxcr4     0.0033865260 -0.083185096  0.013639883  0.0035759456  2.864629e-02
#> Hrh2      0.0103471336  0.026383435  0.075884162  0.0206014597 -2.660904e-02
#> Slc17a6  -0.0008164387 -0.085923213  0.041082598 -0.0233140484 -1.242422e-02
#> Ppp1r3g  -0.1384504309 -0.099999760  0.036140294 -0.0796807691  2.628760e-01
#> Pln       0.0445109637 -0.014511131 -0.002485981  0.0051608577  4.888129e-02
#> Grin2b    0.0144133022 -0.030925128 -0.006750256  0.0361246426 -2.548812e-02
#> Taar7e   -0.0124750682 -0.031609189 -0.009036898 -0.0059682948  3.014806e-04
#> Ptger2    0.0764166989  0.093908008  0.112207441 -0.0096151290 -3.695083e-02
#> Mc4r      0.0472528642  0.072213711 -0.077193292 -0.0270830176  3.346141e-03
#> Ghsr      0.0052447572 -0.051142392  0.053817262 -0.1259749510  4.283643e-04
#> Nmbr      0.1145647537 -0.222794650 -0.228934077 -0.0086525620 -2.723308e-02
#>                Dim.31        Dim.32        Dim.33        Dim.34        Dim.35
#> Mlc1      0.046828468 -0.0598006726  2.728154e-02 -0.0447370101  0.0494032685
#> Gprc5b    0.043139566 -0.0645482478 -4.625959e-02 -0.1079741072 -0.0032662485
#> Gfap     -0.084451969  0.0189433844  7.755266e-02  0.0284905859  0.0887666941
#> Ednrb    -0.039601795  0.0165999322  1.015626e-02  0.0763068193  0.0267904621
#> Sox9     -0.006622427  0.0753248866  5.675914e-03 -0.1282415159 -0.0636306132
#> Aqp4      0.057116490 -0.0190713689 -5.925918e-02 -0.0139270737 -0.0245126799
#> Gjc3      0.013838298 -0.0216097008  2.018414e-02  0.0688803634 -0.0659016395
#> Sox8     -0.039792363  0.1001053422  4.248161e-02  0.0892288804  0.0159415039
#> Ntsr2     0.026916552  0.1789323057  8.604315e-02  0.1125314756 -0.1358046150
#> Smo      -0.019469457  0.0586247767  6.891104e-03 -0.0333074462  0.0279408821
#> C1qb      0.012424437 -0.0150347314 -7.047393e-02 -0.0418619337  0.0062502262
#> Olig1     0.066097899  0.0351040968 -8.447867e-03  0.0233609796  0.0013404769
#> C1qa      0.082729243 -0.1669126528 -7.458389e-03  0.1849357542 -0.0376629693
#> Pth1r     0.121885666  0.0380139862 -2.840862e-02 -0.0002658282 -0.0791146653
#> Gabbr2    0.090371961  0.0372215327 -1.220097e-01  0.0435938288 -0.0009317162
#> Timp4    -0.086464280  0.0933513361  4.923471e-02  0.0253984833  0.1920992832
#> Abcc9    -0.084384393 -0.0610777513  5.785971e-02  0.0807878971 -0.0338071616
#> Csf1r    -0.152633159  0.0473608548  4.269237e-02  0.1128218638 -0.0583104455
#> Ntrk2    -0.063591663 -0.1392178360 -4.827163e-02 -0.1001359086 -0.1637454518
#> Adgrg1    0.049207360 -0.1073650837 -8.895728e-02 -0.0377169187 -0.0318250457
#> Ntrk3    -0.111887148 -0.0711837646  4.267670e-02  0.0082900974 -0.1252205428
#> Erbb4     0.025227279 -0.0178451823 -1.220885e-02 -0.0374746419 -0.0142466855
#> Selplg    0.081529945 -0.0201341489 -1.323207e-02 -0.0154868793  0.0379776326
#> Cspg5     0.089496955 -0.0694036862  3.120273e-02 -0.0360626007  0.0188246325
#> Dlk1      0.149039116 -0.1877217986 -1.643182e-01 -0.0652078950 -0.0561248429
#> Gpr37l1  -0.024429701 -0.1005289171 -8.153428e-02 -0.0329499715  0.0363414821
#> Fgfr3     0.019317224 -0.0497822886  2.938358e-02  0.0011134531  0.0805321248
#> Slc25a18 -0.050743001 -0.0296061196  2.556011e-02 -0.0433518931 -0.2193483209
#> Igf1r    -0.076530319 -0.0062404586 -4.564518e-03 -0.0197511675 -0.0701019182
#> S1pr1    -0.021106526 -0.0134251511 -6.357475e-02 -0.0125899223  0.1420520110
#> Grm5     -0.234083083 -0.0954584451 -3.330167e-02  0.0028860124 -0.1660879724
#> Axl       0.044156482 -0.0599993938  1.419222e-02  0.0309315854 -0.1077802711
#> Efemp1   -0.063266484 -0.0088457345  9.670566e-02  0.0566883551  0.0119269021
#> Adgrb3   -0.153774463 -0.0635340697  9.247846e-03  0.1384534955  0.2085176516
#> Fn1      -0.021249829  0.1305903254  4.301929e-02 -0.1323524685 -0.1096978955
#> Mertk    -0.102921918  0.1281939202  1.623788e-01  0.2094871600  0.0207791043
#> Adgrl2   -0.007860873 -0.0021973300  5.234147e-02 -0.1777774342  0.0409187098
#> Fzd2      0.030239235  0.0124965190 -2.269772e-02 -0.1275234384  0.0133330593
#> Aldh1l1  -0.035923302  0.0644376425  1.734290e-02 -0.0587820633  0.0835981892
#> Adgrg6    0.069634243 -0.0587408715 -5.638447e-02  0.0099802747  0.0025818605
#> Egfr     -0.016326186 -0.0320479785 -6.859912e-05  0.1188884863  0.0085784392
#> Kit      -0.108737744  0.0852250667  9.599120e-02  0.1831727742 -0.1136392621
#> Ptgdr     0.019292896  0.0063555982 -4.826008e-02  0.0236474095  0.0269023481
#> Gad1      0.079657186 -0.0686074025 -4.335263e-02 -0.0771170862  0.0970554815
#> Tyro3     0.007539715 -0.0473039552 -3.568943e-02  0.0048044510  0.0286580500
#> Atp13a5  -0.006673755  0.0406455961  3.314240e-02 -0.2153231253  0.0201205947
#> Ddr2     -0.050036007 -0.0780244812  2.745486e-02  0.0928642216  0.1728063915
#> Rspo3     0.076118504  0.0238444237 -1.971699e-02  0.0677722837  0.0314639576
#> Arhgap29  0.012956082 -0.0694323961 -4.035540e-02  0.0135653452 -0.0120986106
#> Fzd7      0.014305674  0.1149147747  7.358168e-02  0.0346162309  0.0129175265
#> Slc47a1   0.012151578 -0.0831412240 -5.128258e-02  0.0155157148  0.0398152983
#> Ptger3   -0.058215780 -0.1489129512 -1.210736e-01  0.1115972400 -0.0120655440
#> Bdkrb1    0.067141336  0.0172753971 -1.802968e-02 -0.2273791512 -0.0992594890
#> Traf4    -0.011866296  0.0004981121 -4.951589e-03 -0.0912585027 -0.0355982296
#> Cx3cr1    0.024277900  0.0352343790 -1.212546e-03 -0.0963795964  0.0462792154
#> Anxa11   -0.002117323 -0.1968707311  1.251938e-01  0.0670237421 -0.1275454963
#> Adgrb1   -0.173912641 -0.1415132139  1.644371e-01 -0.1000261924 -0.1520951604
#> Lpar1     0.038127523 -0.2163020820 -9.496572e-02  0.0329034433  0.0638695741
#> Gpr17    -0.026323726  0.0388872221 -9.339464e-03 -0.0058489438  0.0379973241
#> Cxcl12    0.069416771  0.0506034263 -9.995949e-02  0.0425253996  0.0201389086
#> Epha4     0.056675874  0.0129259063  3.203585e-03  0.0179203115  0.0701734213
#> Gpr182    0.007513760  0.0845145986  9.137210e-02  0.0456192044  0.0147780005
#> P2ry14   -0.103551340 -0.1744112679 -5.322856e-02  0.1540049073  0.0163092480
#> Hcar1    -0.012512550  0.0870098305  2.631313e-03  0.0591000044 -0.0549805473
#> Ephb1    -0.064536802  0.0954271249  9.844991e-02  0.0572161968 -0.0388351299
#> Grm3     -0.035388021 -0.0259657636  2.541851e-04  0.0579422133  0.1305167588
#> P2ry1    -0.039865513 -0.0867544513 -1.093052e-02 -0.0094270283 -0.1347780920
#> Ptk7     -0.148622402 -0.0032059121 -7.716997e-02 -0.0435938209  0.1875523254
#> Slco1a4  -0.009672401 -0.0766497669 -5.563207e-02  0.0127129950  0.0216604487
#> Insrr     0.041762445 -0.0735588622 -1.072453e-02  0.0344998779  0.0853711705
#> Cmklr1   -0.073411183  0.0729766849  3.692986e-02  0.0334058808  0.0186064318
#> Fzd6      0.048545810  0.0841069983  4.021975e-02 -0.0765074943 -0.3001476592
#> S1pr5     0.003558514  0.0183656052  2.431260e-02 -0.0456651753 -0.0083827503
#> Pdgfrb    0.095926352  0.0462783166 -4.922459e-02 -0.1033001766  0.0362304442
#> Flt1     -0.012908200  0.0201207566  2.591138e-02 -0.0023468483 -0.0997050023
#> Adgrl4    0.109940514  0.1702367828  1.635577e-02 -0.0102367887 -0.1158632033
#> Lpar6    -0.176544128  0.2254068050  3.661908e-02 -0.1176513654 -0.0090381637
#> Epha6    -0.025988125 -0.0540053868  1.431176e-01 -0.1163527588  0.0928768639
#> Emcn      0.065982344  0.1227126807  6.668498e-02 -0.0217861866  0.0412138114
#> Cldn5    -0.069025765 -0.0435180826  2.949371e-02 -0.0016895091  0.1635148788
#> P2ry12   -0.023892123 -0.0160430920  1.215217e-02 -0.0679104842  0.0217107768
#> Adgrf5    0.065615569 -0.1000101407 -3.363524e-03  0.0902798957  0.0492302079
#> P2yr13    0.081844806 -0.1299638028 -5.584187e-02  0.0512208005 -0.0410498812
#> Adgre1    0.022579107 -0.0041167572  6.838308e-02 -0.1287046926  0.0487000771
#> Cx3cl1    0.220527393  0.0780650401 -1.431374e-02  0.0131880459  0.1633746357
#> Plxnb3    0.138582381  0.0010790332 -8.468542e-02 -0.0441258190 -0.0894258803
#> Flt4     -0.022974074  0.0076688861 -2.626752e-02 -0.0505514850 -0.0654974113
#> Slc17a7   0.300845666  0.1582499632  2.062201e-02  0.1066829830  0.0546577076
#> Cd300c2  -0.035958983  0.0981355804  8.655646e-03 -0.1665114222 -0.0190512954
#> Tek      -0.039842924  0.0342239248  1.347741e-03  0.0026123442  0.1472952488
#> Kdr      -0.020023374 -0.0874993765 -4.948848e-02  0.0556506639 -0.0064641496
#> Kcnj8    -0.059145594 -0.0433822437  6.304247e-03  0.0736169850 -0.0416797079
#> S1pr3    -0.008363763  0.0283323618  3.141338e-02  0.1134452541 -0.0397475771
#> Tie1     -0.019658018 -0.0394992963 -3.931671e-02  0.0194922677 -0.0953385382
#> Pdgfra   -0.040746646 -0.0797455783  1.714363e-02 -0.0865522199 -0.0509739034
#> Baiap2   -0.060755466 -0.0232509619  1.864062e-02 -0.0520752461  0.0255375312
#> Calcrl   -0.010114340 -0.1490642491  3.701947e-02  0.0965929504  0.0808241665
#> Adrb2    -0.042443886  0.0457706002  1.095481e-01  0.0394581013 -0.0804562647
#> Ccr2      0.052244168  0.0349708865 -6.291725e-02 -0.1560912744  0.0007372440
#> Alk       0.002457115  0.0193345489  6.111945e-02  0.0954399201  0.0496196240
#> Tacr3     0.063014434  0.0090085198  8.880871e-02  0.1086158422  0.0087241236
#> Erbb3    -0.035547031  0.0156821802  2.053372e-02 -0.1219785893 -0.0152604550
#> Pcdh15    0.015756330  0.0416455279 -3.092840e-02 -0.0184354526  0.0008065560
#> Grm7     -0.363749647 -0.0996376725 -7.967975e-02 -0.1242796748 -0.0816284023
#> F2r      -0.035856448 -0.0233279613  6.984108e-02  0.0959805202  0.0058801195
#> Bdkrb2    0.047983723 -0.0300023848 -1.814729e-01 -0.2887648702  0.1216281904
#> Adgrv1   -0.020518436  0.0127412933  4.092209e-02  0.0724540105  0.0447967700
#> Gprc5c    0.024902804  0.0877821129 -2.039111e-02  0.0615017823  0.0072692591
#> Tbxa2r    0.101752456  0.0637760717 -5.673629e-02  0.0118845179  0.0227262969
#> Ackr1    -0.064746410  0.0695407938 -1.187198e-02 -0.0904984610 -0.0710609276
#> Lpar2    -0.125029267  0.0204099466  3.052365e-02 -0.0438830232  0.0037824978
#> Myh11     0.091560936 -0.0414864920 -1.467731e-02 -0.0157910353 -0.0773840292
#> Musk     -0.014367541 -0.0698388453 -2.087723e-02 -0.1051635181  0.0750837693
#> Cnr1     -0.028825368  0.1360820946  8.153354e-02  0.0042860682 -0.0613969703
#> C3ar1    -0.107270182  0.1829165121  4.049878e-02 -0.0819728312  0.0598627527
#> S1pr4    -0.010424609  0.0573312489  3.275797e-02  0.0039531567 -0.0286053617
#> C5ar1     0.010422077 -0.0961241976  1.629990e-02  0.0317985102  0.0618174150
#> Fpr1     -0.016006759  0.1021449753  4.216517e-02  0.0487268964  0.0491982198
#> Sctr     -0.007395809 -0.0195678116  1.143698e-02  0.0155668037  0.0965021426
#> Gpr158   -0.116567139 -0.0108367875  3.243604e-02 -0.0712450487  0.0089005696
#> Cxcr4     0.013367688 -0.0067748190  2.585866e-02  0.0018319666 -0.0134507343
#> Hrh2     -0.139398040 -0.0291304104 -5.949163e-03 -0.0481852135 -0.0997687187
#> Slc17a6  -0.004612063  0.0630069893  3.650120e-02  0.0082822799  0.0213399951
#> Ppp1r3g  -0.080239074  0.1485934844 -8.515849e-03 -0.0923543880  0.1760423755
#> Pln       0.064400597 -0.0366968064 -2.027069e-02 -0.0219495922  0.0470307311
#> Grin2b   -0.048447452  0.0027897013 -8.976805e-02  0.0577922127 -0.0844752800
#> Taar7e   -0.008864837 -0.0358847537  2.822804e-02  0.0176690791 -0.0261339415
#> Ptger2   -0.254762975 -0.0129889699  8.403887e-03 -0.1382598346  0.3049073902
#> Mc4r      0.003322849  0.1230615140  6.443982e-02  0.1014378478  0.0310941899
#> Ghsr      0.215464544 -0.2932875291  7.425669e-01 -0.1957352497  0.0696802111
#> Nmbr     -0.106036672 -0.1269402661 -1.176558e-02  0.0450735836  0.0620510011
#>                 Dim.36       Dim.37        Dim.38        Dim.39        Dim.40
#> Mlc1     -0.0184651881 -0.030304498 -0.0160638709  0.0416501378  5.361885e-02
#> Gprc5b   -0.0939820092 -0.008529965  0.0350760268 -0.2553544395 -1.522452e-01
#> Gfap      0.0262586593  0.072650046  0.0113510685 -0.0715659259  9.849332e-02
#> Ednrb     0.0982531407 -0.104714980  0.0500510838 -0.1137377850 -1.269958e-01
#> Sox9     -0.0371162158 -0.151044779  0.1472019918 -0.0006830817 -1.397952e-01
#> Aqp4     -0.0390975216 -0.029896340 -0.0782866404  0.1162288178 -1.292995e-01
#> Gjc3      0.0468822349 -0.108358110 -0.1102798835  0.1361553064 -6.362949e-02
#> Sox8     -0.0601223808  0.060710974 -0.0614759031  0.1619193810  1.584736e-01
#> Ntsr2     0.1232741324  0.225969719  0.2488331589  0.0844487918  1.063193e-01
#> Smo      -0.0840642444  0.031353996  0.0023371307 -0.0484884572 -3.846325e-02
#> C1qb      0.0497127529  0.023999045 -0.0125238911 -0.0884486690  1.314621e-02
#> Olig1     0.0020762266 -0.047091326 -0.0503973505  0.0003963190 -6.083122e-02
#> C1qa      0.0754253599 -0.130997264  0.0978677252 -0.0278780722  2.200412e-02
#> Pth1r    -0.0030838041 -0.121727640  0.0059440802  0.0256618653 -3.905047e-02
#> Gabbr2    0.0808922385 -0.002790812  0.0233899836  0.0168918251  1.057552e-02
#> Timp4    -0.1270588590 -0.100894925 -0.1736479716 -0.0504274565  2.340758e-02
#> Abcc9     0.0187054444  0.011617286  0.0263868077 -0.0053857508 -1.218239e-01
#> Csf1r     0.1318275669 -0.163527135 -0.0838633215 -0.0052300633 -5.196351e-02
#> Ntrk2    -0.0398631515  0.085021496  0.0212158985  0.0415714242  4.249104e-02
#> Adgrg1   -0.0976986661 -0.012428502 -0.0988359397  0.1831834716 -4.760026e-02
#> Ntrk3    -0.0639744569  0.060570611  0.0078495448  0.0142525062  3.130265e-02
#> Erbb4    -0.0167264390 -0.016592544  0.0789511757  0.0093986326  7.037000e-02
#> Selplg   -0.0341170962  0.002527291 -0.0067316310  0.0186744185 -1.170480e-02
#> Cspg5     0.0680101482 -0.054979539  0.1151432372 -0.0593981661 -1.510112e-01
#> Dlk1     -0.0353745449 -0.218198801 -0.0375729362 -0.0670524620  3.335269e-02
#> Gpr37l1  -0.1523234693 -0.086291714 -0.2568447779  0.1904020485  5.128738e-02
#> Fgfr3     0.0642415927 -0.006308800 -0.0259544162 -0.1127973279  1.599982e-02
#> Slc25a18 -0.0465369947 -0.043853335  0.1848435107  0.1450936692  8.717011e-03
#> Igf1r     0.0399526150  0.026603673 -0.0788252706 -0.0306618990  7.775312e-02
#> S1pr1    -0.0325449201 -0.177263266 -0.2322677195 -0.1147150551  1.007809e-01
#> Grm5     -0.2516548488  0.018275587 -0.0514854108 -0.1098154125  2.549782e-02
#> Axl       0.0904061274 -0.078917037 -0.0569383991  0.0040041984  3.185887e-02
#> Efemp1   -0.0582386384 -0.020314725  0.0286624622  0.1112548354  6.487451e-02
#> Adgrb3    0.2126002272  0.018012550 -0.0611417626 -0.2114866671  1.160864e-01
#> Fn1       0.0234489932 -0.100600776 -0.0637769322 -0.0800411776  3.423702e-03
#> Mertk    -0.0220847008  0.048399868  0.0012613628 -0.0230931269 -5.811036e-02
#> Adgrl2   -0.1018121809 -0.039244339  0.1214987147  0.0966271918  6.848295e-04
#> Fzd2      0.0630975631  0.066823082 -0.0439847934 -0.0855735417 -6.062035e-05
#> Aldh1l1   0.0253316439 -0.035522819  0.0749115497 -0.0114900494 -6.626741e-02
#> Adgrg6    0.0537950862  0.241274154 -0.2195531775  0.0683674891 -2.408349e-01
#> Egfr     -0.0449813943 -0.010427737 -0.0072195101 -0.0074096746 -3.434149e-02
#> Kit      -0.0455521661 -0.084265229 -0.0346420438 -0.0145615556 -2.873945e-01
#> Ptgdr     0.0240254379  0.016648187 -0.0082421640  0.0044110074  7.595321e-02
#> Gad1      0.0795709522  0.028364256  0.0256205028  0.0613774902  6.682388e-02
#> Tyro3    -0.0722179570 -0.004041765 -0.0364148299 -0.1265511842 -7.153692e-03
#> Atp13a5  -0.0119193160  0.084586335  0.0006471908  0.0268182075 -7.756046e-02
#> Ddr2     -0.1338285901  0.025562956  0.1088641291  0.0549546481  6.355574e-02
#> Rspo3    -0.0044048184  0.011137614 -0.0138205060  0.0446353461 -2.149552e-03
#> Arhgap29 -0.0037139699 -0.011861371  0.0182434276  0.0652955305  4.654955e-02
#> Fzd7     -0.0502677342 -0.154618812  0.0863160473  0.0409111381 -2.471826e-02
#> Slc47a1   0.0224130779  0.003298689  0.0590472108 -0.0082628625 -4.528392e-02
#> Ptger3    0.0384768157 -0.049609578 -0.0071401496  0.0388993023  1.089749e-02
#> Bdkrb1    0.0270953361  0.009568066 -0.0759762411 -0.0072058860 -1.084141e-01
#> Traf4     0.0296824167 -0.016055322  0.0370464471  0.0136527758 -1.314091e-02
#> Cx3cr1   -0.1636810075  0.018512548  0.0386548891  0.1218234193  1.213436e-01
#> Anxa11    0.0508793245  0.023968906 -0.0667699889  0.0577319260  6.406210e-02
#> Adgrb1   -0.1725663835 -0.018179117 -0.0451824695 -0.0668524372  8.222429e-02
#> Lpar1    -0.0367472609 -0.116111132  0.1306757422 -0.1388211577 -1.317296e-01
#> Gpr17    -0.0297323810  0.028825072  0.0105482531 -0.0419610908  8.285689e-02
#> Cxcl12    0.0346060269  0.098685686 -0.1628733629  0.0578450895  4.298889e-02
#> Epha4     0.0135408213 -0.025926931  0.0254810852 -0.0050918601 -6.727591e-02
#> Gpr182   -0.0748048751  0.027327328  0.0835617206 -0.0064135173 -2.937942e-02
#> P2ry14   -0.0265676971 -0.174716836  0.1122414679  0.0567899290 -8.275995e-02
#> Hcar1     0.0165664308  0.050496632 -0.1165294466 -0.0351025722  8.169078e-02
#> Ephb1     0.0590708642  0.135181704  0.1128769853  0.0709783108  9.179299e-02
#> Grm3      0.0118479689  0.115666854  0.0235324871 -0.1569341816  1.927289e-01
#> P2ry1     0.1072456043  0.007266877 -0.0472425354  0.0838375817  1.468678e-01
#> Ptk7      0.0823052562  0.036186688 -0.0676373468 -0.0502177537 -3.600953e-03
#> Slco1a4   0.0077821794  0.032812009  0.0538668681 -0.0335722688  8.466779e-03
#> Insrr     0.0381300985  0.045587348  0.0321365280  0.0260483808  2.870478e-01
#> Cmklr1   -0.0740175255 -0.115472686 -0.0577966977  0.0792883802 -2.944634e-02
#> Fzd6      0.2070182469 -0.016673717 -0.2233819981  0.0178819476  3.697770e-02
#> S1pr5    -0.0033012816  0.061338714  0.0764305623  0.0413469057  2.639493e-02
#> Pdgfrb    0.0158029721  0.011404295 -0.1066469405  0.0148675119  1.414339e-01
#> Flt1      0.1009801665 -0.101288027  0.0191020162 -0.0815439050  6.693099e-02
#> Adgrl4    0.1272835024 -0.069567390  0.0804360659 -0.0866085252  1.376898e-02
#> Lpar6    -0.0586611705  0.080686514 -0.0012916598 -0.0274952559 -2.068817e-01
#> Epha6     0.0401898133 -0.015209634 -0.0283085247  0.1162029646 -9.925700e-02
#> Emcn     -0.1110714310  0.015489320 -0.0541160786 -0.0757955706  1.038678e-02
#> Cldn5    -0.1473402691 -0.003748776  0.1145678035  0.1063738699 -3.154296e-02
#> P2ry12    0.0087181022  0.152456837 -0.0246374030 -0.0501469131 -1.167572e-02
#> Adgrf5   -0.0731615024  0.251256309 -0.0753575003  0.1195170426 -2.033394e-01
#> P2yr13    0.0958447599  0.019205108  0.0086681309 -0.0262129339 -1.625402e-02
#> Adgre1   -0.1236192018  0.143904415  0.0104344192  0.0514115871 -5.733619e-02
#> Cx3cl1   -0.0111607015 -0.057099476  0.0367622389  0.0377961096 -1.014273e-01
#> Plxnb3   -0.0580301919 -0.177218373  0.0272946573  0.0619157127 -3.814762e-02
#> Flt4      0.1564807450 -0.049635448  0.0895078862 -0.1678011944  6.297056e-02
#> Slc17a7  -0.0626166295 -0.044459061  0.0484938798 -0.0097180309 -8.290817e-02
#> Cd300c2  -0.0527411828  0.113588822  0.0684308802  0.0530322867 -6.811482e-02
#> Tek      -0.1075037452 -0.181204847  0.1554732761  0.0277579229  9.678577e-02
#> Kdr      -0.0154287112  0.135188283 -0.1020429449  0.0387922063  5.634872e-02
#> Kcnj8     0.0160907110 -0.068873197  0.0285474299  0.0377063746 -5.337167e-02
#> S1pr3     0.0067908368 -0.025080717  0.0175108476 -0.0284456087  5.661047e-02
#> Tie1      0.1751761731 -0.003997850 -0.0373416228 -0.0754304033  3.054548e-02
#> Pdgfra    0.1216957063  0.063385337  0.1436888751 -0.1584631690 -1.639057e-01
#> Baiap2    0.1290711197 -0.037772225  0.0080747252  0.1325683913  9.908312e-03
#> Calcrl   -0.0783124314  0.087704244  0.0471934587  0.0327874872 -1.070924e-01
#> Adrb2    -0.0357940475  0.018562977 -0.0904828555 -0.0090089510 -1.300637e-01
#> Ccr2      0.0252828342  0.090584788 -0.0833943831 -0.0632729178 -1.630121e-02
#> Alk      -0.0492032970  0.019157148 -0.0264414335  0.0416550702  1.255275e-02
#> Tacr3    -0.0535589138  0.004730896 -0.0425153666 -0.0051265568 -9.853447e-03
#> Erbb3     0.0236258806  0.074459182  0.1138411718  0.0812697470 -1.703117e-02
#> Pcdh15   -0.0004332264 -0.035596986 -0.0727413870  0.1276550097  5.727905e-03
#> Grm7      0.0254595499 -0.032995583  0.0297535758  0.0594028503 -2.223731e-02
#> F2r      -0.0211161929  0.153332854  0.0863454750 -0.1951097109 -3.424781e-03
#> Bdkrb2   -0.0157341585  0.023271118  0.1367030101 -0.0248522751  1.484751e-01
#> Adgrv1   -0.0153838170 -0.003352800  0.0724944583 -0.0152677536  1.010589e-01
#> Gprc5c    0.0102780406  0.033180746 -0.0241477500 -0.0110264477  5.397094e-02
#> Tbxa2r   -0.0558196749  0.020794635 -0.0699801286  0.0518509430  7.055661e-02
#> Ackr1    -0.0213723098 -0.148936468 -0.0978936909 -0.0316796292  1.488596e-01
#> Lpar2    -0.0247879032 -0.122258220  0.0836873154  0.0514119058  3.079012e-02
#> Myh11     0.1154721096  0.085550607 -0.0590846312  0.0143622993 -2.695850e-02
#> Musk      0.0388165365 -0.041598096  0.0968544371 -0.0135082858 -4.084980e-02
#> Cnr1     -0.0214784697  0.016354044 -0.0680501854 -0.0844704614 -3.088668e-03
#> C3ar1    -0.0887895541 -0.056778803 -0.0517207885  0.0808060811  1.147404e-01
#> S1pr4     0.0471935318 -0.111264085  0.0106246804 -0.0247261562  2.333620e-02
#> C5ar1    -0.0122438345  0.267574304 -0.0509031489 -0.0755295187 -4.173971e-02
#> Fpr1     -0.0792090017 -0.123477018  0.0769766045  0.0049321412  2.671077e-02
#> Sctr     -0.0196127403 -0.024961104 -0.0077775181 -0.0198646814 -4.114963e-02
#> Gpr158    0.0503474194 -0.031459724  0.0166471130  0.0404700763  5.551943e-02
#> Cxcr4     0.0219997126  0.009940269  0.0754621830 -0.0315285395 -2.099672e-02
#> Hrh2     -0.1401452112  0.033707427 -0.0028436899 -0.1002431670 -3.916837e-02
#> Slc17a6  -0.0034701078  0.006230451  0.0148829739 -0.0309501901  1.716244e-03
#> Ppp1r3g  -0.0016334887 -0.089571735 -0.2226436240 -0.2746964147 -8.193983e-02
#> Pln      -0.0367428755 -0.002472797 -0.0022713359  0.0981751355 -2.531201e-02
#> Grin2b   -0.0899627373  0.035254581  0.0399758963 -0.0229135939  6.190592e-02
#> Taar7e    0.0301153876  0.028150223  0.0011443092 -0.0257971309  3.282681e-02
#> Ptger2    0.4568251485 -0.040841050  0.0250627486  0.2762322424 -1.432585e-01
#> Mc4r      0.1457895275 -0.080847123 -0.0888988041  0.2005187302 -1.070330e-02
#> Ghsr      0.0439222964 -0.091800363 -0.0993547255 -0.0464195668  7.397257e-02
#> Nmbr     -0.0646141507 -0.048184095 -0.2148970819  0.0432620435 -9.744349e-02
#>                 Dim.41       Dim.42       Dim.43        Dim.44        Dim.45
#> Mlc1      0.0643317341 -0.054764478 -0.174173415 -0.0923818740 -5.516297e-03
#> Gprc5b   -0.1021655180 -0.086213482 -0.105730502 -0.2534479133 -4.052155e-02
#> Gfap      0.0740504391 -0.041887867 -0.051935363 -0.0373155836 -2.432162e-03
#> Ednrb     0.0551232520  0.127999610  0.056461436  0.0579064124  2.568717e-02
#> Sox9     -0.0773481265  0.067782335  0.103099053 -0.0506625942 -7.112397e-02
#> Aqp4     -0.0516671195  0.097115387  0.142334263  0.1297990393 -1.181859e-02
#> Gjc3      0.0327259722  0.099922776  0.025632795 -0.0205891646  1.336047e-01
#> Sox8      0.0985313502 -0.112960344  0.025851437 -0.1551140998 -1.326157e-01
#> Ntsr2     0.0785200532 -0.114059990 -0.166204969  0.0204349901 -7.038725e-02
#> Smo      -0.0250814320 -0.038439680 -0.196627335  0.0452529613  1.820839e-01
#> C1qb      0.0212880572 -0.035488603 -0.015494208 -0.0330613409  6.395891e-02
#> Olig1     0.0253190839  0.017203247 -0.054599251 -0.0255273149  8.029054e-02
#> C1qa     -0.0135661511  0.037661404 -0.022047380  0.1568863111 -6.369763e-02
#> Pth1r    -0.0463781685  0.105152855 -0.007516537  0.0006439744 -3.570192e-02
#> Gabbr2   -0.0316439992  0.033223605  0.007232072  0.0014817700  2.633256e-02
#> Timp4     0.0588784958 -0.091471303  0.031377151  0.0583792125  1.494263e-02
#> Abcc9    -0.1109384449 -0.090681367 -0.073249093  0.0462842256  2.509298e-02
#> Csf1r    -0.0362950700  0.281248936  0.033717027 -0.1279655728 -5.613931e-02
#> Ntrk2    -0.1974515406 -0.034326054 -0.042678658 -0.0587749706  6.616282e-02
#> Adgrg1   -0.0383849797  0.048048074 -0.022739842  0.1498210432  1.316412e-01
#> Ntrk3    -0.0009595687 -0.032379267  0.158116075 -0.0451758739 -1.548037e-02
#> Erbb4    -0.0317971617  0.009962084  0.131608987 -0.1085651614  2.160674e-01
#> Selplg    0.0304610903 -0.117080780  0.020348523  0.0619208915  5.391372e-02
#> Cspg5     0.1009722957  0.016925344  0.037964084  0.0070723766 -4.276894e-03
#> Dlk1     -0.0381672000 -0.109022077 -0.006967999 -0.0488579536 -4.593968e-03
#> Gpr37l1  -0.0275785666 -0.019553809  0.254841214  0.0687479732  6.891691e-02
#> Fgfr3    -0.0005879796 -0.102328219  0.014884693  0.0545803003 -1.367574e-02
#> Slc25a18  0.0125550580  0.013679255 -0.208341235 -0.0364212544  1.823488e-01
#> Igf1r     0.1225668687  0.086411412 -0.063731591  0.1148387934 -1.373221e-02
#> S1pr1    -0.0633881381 -0.034127895  0.118770093  0.0579468371 -2.324412e-02
#> Grm5      0.0233830214 -0.001035762 -0.010456036  0.0124027827 -3.124437e-02
#> Axl       0.0074748291 -0.104766730 -0.017936965 -0.2031400035  1.936683e-02
#> Efemp1   -0.1488280631  0.027576071 -0.031953277  0.0145686118 -7.206308e-02
#> Adgrb3    0.2572227294  0.123914398 -0.067619456  0.0652661523  2.012681e-01
#> Fn1      -0.0255747186  0.034445417  0.094843573  0.0833642077 -7.105043e-02
#> Mertk     0.0767727788  0.138501387 -0.025807046 -0.1408189951 -1.005566e-01
#> Adgrl2   -0.0240220259  0.015997072  0.003344261 -0.1110349288 -3.838102e-02
#> Fzd2     -0.0606452445 -0.017963464 -0.007685615 -0.0237867403 -3.073157e-02
#> Aldh1l1  -0.0034666362  0.117546407  0.020814691  0.0322193967  3.682676e-02
#> Adgrg6    0.1414064016  0.140698465 -0.014073069 -0.1387687972  3.506657e-02
#> Egfr      0.0558185903  0.005256354  0.075116458  0.0199596118  8.231042e-02
#> Kit       0.0087070321 -0.178334333  0.046879683 -0.0640861680  7.038962e-02
#> Ptgdr     0.0736573806  0.131322670  0.025843988 -0.0216869608 -3.697933e-02
#> Gad1     -0.0396407508  0.036907797  0.051970643 -0.0149179111  2.973331e-02
#> Tyro3    -0.0064362358 -0.054881942 -0.047964494 -0.0228024468  8.213397e-02
#> Atp13a5   0.0384860186 -0.031310490 -0.020471104 -0.0543620856  1.208858e-02
#> Ddr2     -0.0626974873 -0.136709620 -0.007516952  0.0335426958  9.787339e-02
#> Rspo3    -0.0309039275  0.007325428  0.048003881 -0.0486419449 -8.835275e-03
#> Arhgap29  0.2237371425 -0.026624138  0.051350991  0.0419043496  1.204373e-01
#> Fzd7      0.1678221524  0.048668836 -0.007165167  0.1620989999  2.228624e-01
#> Slc47a1   0.0928683087 -0.025838626 -0.004168962 -0.0462685562  1.755251e-02
#> Ptger3    0.0249441519 -0.001156395  0.066937072 -0.1144621314 -1.752300e-01
#> Bdkrb1   -0.0085581111  0.002578463  0.047835175 -0.0263849742 -1.242401e-01
#> Traf4     0.0391640386  0.047990809 -0.009616797 -0.0261957322 -5.084471e-02
#> Cx3cr1    0.0938215373 -0.153063345 -0.019751679 -0.0025127260 -2.515914e-02
#> Anxa11   -0.0691047768  0.044786100  0.101128845 -0.0897481016 -1.890360e-01
#> Adgrb1   -0.0202667639  0.032484300 -0.038693140 -0.0397780956  1.208404e-01
#> Lpar1     0.0441309496 -0.067667745 -0.099856535 -0.0865986103 -6.077921e-02
#> Gpr17    -0.1071898757 -0.026963294 -0.017954576 -0.0075553221 -4.570432e-02
#> Cxcl12   -0.0585808077 -0.018787414 -0.162147952  0.1595591740  1.395589e-01
#> Epha4     0.0768834015  0.075467766 -0.019952318  0.0502040560  3.346546e-03
#> Gpr182   -0.0332409530  0.053377236  0.059545265  0.1059979898 -9.267929e-02
#> P2ry14    0.0726907181 -0.025061899  0.079530561  0.0112854547 -6.369785e-02
#> Hcar1    -0.1633868715 -0.097974787 -0.008102099  0.0059583586  3.634126e-02
#> Ephb1     0.0710242059  0.008265060 -0.011766185 -0.0336930429 -1.246034e-01
#> Grm3     -0.1163558580 -0.089911134 -0.009700036 -0.0040474147 -3.799352e-02
#> P2ry1     0.0427740614  0.043239623  0.078023330  0.0319931904  5.880956e-05
#> Ptk7     -0.1738777322  0.052519091 -0.042623964 -0.1358588876  1.645579e-02
#> Slco1a4  -0.1660790632  0.019009683 -0.082900310  0.1029068528  2.165118e-02
#> Insrr    -0.0928055497  0.163208850  0.022016892  0.0022208850 -6.100030e-02
#> Cmklr1   -0.0590268033  0.059089742 -0.037832479 -0.0261682465  1.021090e-01
#> Fzd6      0.0814355924 -0.003491441 -0.045973029 -0.0666552074 -5.901591e-02
#> S1pr5    -0.0598604617 -0.047335127  0.119767018  0.1640621887 -1.027682e-01
#> Pdgfrb    0.0465640210  0.066835296 -0.067035620 -0.0153185467  2.285277e-02
#> Flt1     -0.0092385127 -0.042416897  0.049647706 -0.0583126319 -7.909645e-02
#> Adgrl4    0.0069503370 -0.096620230 -0.027487525  0.0796945660  4.537073e-02
#> Lpar6    -0.1398854117  0.110902226 -0.026424475 -0.0157460599  5.261836e-02
#> Epha6    -0.0369973971 -0.164994019 -0.089436246  0.0168503290 -1.203159e-01
#> Emcn      0.2115045287 -0.121183948  0.179578346  0.0537757069  7.795342e-02
#> Cldn5     0.0613105591  0.076964392  0.040354729 -0.0988317227 -5.127217e-02
#> P2ry12   -0.0989624810 -0.040632207  0.020763570 -0.0522155059  2.673458e-02
#> Adgrf5    0.0828021697  0.089861284 -0.039354838 -0.0764565689  7.172751e-02
#> P2yr13   -0.0106891485 -0.017404493  0.001497426  0.0701777053  2.367790e-03
#> Adgre1    0.1001691670 -0.058688563 -0.013093919 -0.0098932845  2.375173e-02
#> Cx3cl1   -0.0555806187 -0.006286973 -0.022344697  0.0126028107 -9.688128e-04
#> Plxnb3   -0.0627204933 -0.088464068 -0.108271845  0.0101599412  3.946018e-03
#> Flt4     -0.2133975423 -0.125710608  0.052823970  0.0710389894 -3.312774e-02
#> Slc17a7  -0.0505456723 -0.044776726  0.019705770  0.0256305387 -5.015696e-02
#> Cd300c2   0.0100762109  0.050145541  0.092825455  0.1807528684 -5.933996e-02
#> Tek      -0.1690315426 -0.006420412 -0.059917126  0.0687387921 -8.067318e-04
#> Kdr      -0.0216746530 -0.057733516 -0.015496832  0.0194170503  5.277487e-02
#> Kcnj8     0.0048492597  0.047815100 -0.027415876 -0.0174393384  3.705245e-03
#> S1pr3    -0.0133622568 -0.032569877  0.067335411  0.0517770278  8.648706e-03
#> Tie1     -0.0813937966  0.042748703  0.003829562  0.0671889582  8.277435e-02
#> Pdgfra    0.0844983769 -0.052890325  0.115692019  0.1425262203  6.502142e-03
#> Baiap2   -0.0495186221 -0.105370594  0.095621026 -0.0877162658  1.251348e-01
#> Calcrl    0.0171005829 -0.033301150  0.063428463 -0.0668652827 -2.878973e-02
#> Adrb2    -0.0545787266 -0.210736922 -0.006614800  0.1604319958  1.237050e-01
#> Ccr2      0.0486999428 -0.098751510 -0.018711936 -0.0940158727  6.600146e-02
#> Alk      -0.1281344268  0.057304179 -0.058180620  0.0231666822 -3.856565e-02
#> Tacr3    -0.0624874037 -0.060614775  0.054495520 -0.0031829469  6.899449e-02
#> Erbb3    -0.0318475367  0.051369818  0.229836184  0.3004098202 -9.301888e-02
#> Pcdh15   -0.0430571176  0.103826398 -0.111215853  0.0970499275 -3.404765e-02
#> Grm7      0.0308857561  0.034880551  0.017555921  0.1518007948  6.885951e-02
#> F2r       0.0693665195 -0.201531214  0.345891709 -0.0454395100  3.700176e-02
#> Bdkrb2    0.2295575534  0.078549079  0.100648451 -0.0856030137 -7.896300e-02
#> Adgrv1   -0.0449550964  0.041159438 -0.198280336 -0.0178788815  6.412251e-02
#> Gprc5c   -0.0656708945  0.027526430 -0.007290792  0.0359554806  1.067112e-01
#> Tbxa2r   -0.1236270098  0.057306799  0.014556965  0.0090341568 -6.702018e-02
#> Ackr1     0.2019164143 -0.234676721 -0.032979505  0.0005812258  7.227304e-02
#> Lpar2     0.0495377903  0.079276116 -0.013536164 -0.1024118476 -2.978569e-02
#> Myh11     0.0322153722 -0.043370218 -0.015074004 -0.0240286296 -3.526565e-02
#> Musk      0.0990223092  0.094426541 -0.088036548  0.0163395110 -9.953970e-02
#> Cnr1      0.0785426673  0.023099311 -0.133322489  0.1013142557 -1.995846e-01
#> C3ar1     0.0089530762  0.046399448  0.032945168 -0.1216708792 -2.978944e-02
#> S1pr4     0.0300642851 -0.023770659 -0.059571937 -0.0696792762 -2.007499e-02
#> C5ar1    -0.2073652922  0.074308233  0.060042149  0.0687461017 -3.583460e-02
#> Fpr1     -0.0221856605 -0.022539129 -0.007247489 -0.0427372570 -1.640045e-02
#> Sctr      0.0235396431  0.041648525  0.033444745 -0.0225587535 -6.691755e-02
#> Gpr158    0.0329766739 -0.008530823 -0.040119471  0.0551543138  2.482754e-02
#> Cxcr4     0.0110892309  0.010852805  0.017564773 -0.0319806229  4.485823e-03
#> Hrh2     -0.0590743981 -0.010835017 -0.080590549 -0.1044074036 -1.246771e-02
#> Slc17a6  -0.0068493293 -0.018315494  0.012681583 -0.0238077598 -3.252311e-02
#> Ppp1r3g  -0.0526824261  0.107266646  0.015914684 -0.0064860291 -5.238345e-02
#> Pln       0.0109083191 -0.003322155 -0.101150780 -0.0431099968 -3.825230e-03
#> Grin2b   -0.0462492966  0.042369776  0.063174970  0.0331090631  3.820993e-02
#> Taar7e    0.0269635584  0.032332698 -0.042802051  0.0661121035  1.026312e-02
#> Ptger2   -0.0988007030 -0.224716974 -0.050034239 -0.0078701686  6.715279e-02
#> Mc4r     -0.0564594875 -0.179600625  0.228255492 -0.2039794284 -6.088343e-02
#> Ghsr     -0.0314799375  0.100300289 -0.012627397  0.0341753911  7.570183e-02
#> Nmbr      0.1466676367 -0.204003125 -0.254970016  0.2650677475 -4.621425e-01
#>                 Dim.46       Dim.47       Dim.48        Dim.49        Dim.50
#> Mlc1     -3.609612e-02 -0.066023377 -0.053245137 -0.0005666037  0.0005694164
#> Gprc5b   -8.469528e-02  0.156788151 -0.178225691 -0.0430244562 -0.0058373110
#> Gfap     -2.304603e-03 -0.008335894  0.027302635 -0.0095727295  0.0672685467
#> Ednrb    -7.193897e-02 -0.052959499  0.073387052  0.0868422292 -0.0074431370
#> Sox9     -4.431520e-02 -0.020581213 -0.079456079  0.0278801967 -0.0388738143
#> Aqp4      6.480487e-02  0.147580811 -0.036645535  0.0332258593 -0.0662155403
#> Gjc3      7.700075e-03 -0.151583195  0.045329570  0.1172799084 -0.0156182814
#> Sox8      4.742613e-02 -0.090087077  0.163979039 -0.0479065251 -0.1451686967
#> Ntsr2    -3.653848e-02 -0.018134522 -0.048345420 -0.0309826351  0.0105251743
#> Smo       1.877413e-01  0.196898790  0.114488102  0.0718535764  0.0856293831
#> C1qb      2.697623e-02  0.004236971  0.015446251 -0.0043411963 -0.0142665905
#> Olig1    -4.165291e-02  0.009604809 -0.131364599 -0.0439190482  0.1051083608
#> C1qa      4.377265e-02  0.083205303  0.071208712 -0.0013364060  0.1146369009
#> Pth1r    -1.575574e-01  0.096925470 -0.083282442  0.0997044510  0.0510609958
#> Gabbr2   -8.843364e-02 -0.161704077 -0.017095519 -0.0747410166 -0.0106345464
#> Timp4     1.148117e-01 -0.062397296  0.066438613 -0.0242846595  0.1555480638
#> Abcc9     1.094394e-01 -0.133622774  0.100885708 -0.0725002218  0.0606758793
#> Csf1r     1.529788e-01 -0.064328988 -0.086918057  0.0570521826 -0.1610032030
#> Ntrk2    -1.568100e-01  0.020994619 -0.007712980 -0.0071612051  0.0005229980
#> Adgrg1    2.388182e-02  0.017904895  0.008883993  0.0907701719 -0.1134864979
#> Ntrk3     1.106170e-01 -0.038423826  0.166696207 -0.0390014122 -0.0124688828
#> Erbb4     1.116445e-02 -0.011645203  0.009943270 -0.0056019374  0.0400326242
#> Selplg   -5.638070e-02  0.089465919  0.004589622 -0.0548685004 -0.0583841987
#> Cspg5     5.524470e-02  0.030915217 -0.133723908 -0.0156598612 -0.0056119573
#> Dlk1     -1.691182e-02 -0.128126549  0.010692953  0.0109357761 -0.0418994030
#> Gpr37l1   1.316078e-02 -0.070534856  0.139736417 -0.1249194281  0.0115320440
#> Fgfr3     8.364816e-02 -0.053370913  0.007261560  0.0221187734 -0.0028121421
#> Slc25a18 -7.118463e-02 -0.046701857  0.177465437  0.1952373504 -0.1292617254
#> Igf1r     1.026437e-01  0.110101990  0.081509743  0.1102287335 -0.0584441439
#> S1pr1     5.567532e-02 -0.010694832 -0.040164707 -0.0608230405  0.1521623432
#> Grm5      6.201133e-02  0.058192032 -0.034622390  0.0158311712  0.0945483831
#> Axl       1.313275e-01  0.001977299 -0.020392755 -0.0276729913 -0.0806823629
#> Efemp1   -1.022657e-01  0.036512620 -0.046267284 -0.1076514739 -0.0809859402
#> Adgrb3   -4.949285e-01 -0.022663479  0.200950151 -0.0393112140 -0.1533070751
#> Fn1      -1.143007e-01 -0.048965937  0.065166511  0.0948981952  0.0548166495
#> Mertk     7.734030e-02  0.029783392 -0.056683599  0.0415095697  0.2629019425
#> Adgrl2   -1.131086e-01  0.021964402  0.067595697  0.0198870424  0.0162037952
#> Fzd2      4.293113e-02 -0.088300269  0.087094340  0.0845049126 -0.0031670489
#> Aldh1l1   5.108596e-02  0.086922550 -0.065408401 -0.0866080823 -0.1793221836
#> Adgrg6    2.944860e-02  0.106268603  0.031681147 -0.1432775296  0.0241733100
#> Egfr     -9.949434e-02 -0.040076814 -0.003998721 -0.1417275200  0.0466602180
#> Kit      -9.576071e-02  0.049670300  0.011304211  0.0139331049 -0.0969204721
#> Ptgdr     2.987458e-02  0.046214553 -0.040824686 -0.0169567198  0.0861548332
#> Gad1      9.164643e-02  0.022376024  0.025937564  0.0174945240  0.0475197611
#> Tyro3    -1.012704e-01 -0.041053530  0.044575843 -0.0065171212  0.0870308019
#> Atp13a5   9.461724e-03  0.059848088  0.141217643 -0.1080931965 -0.1725735076
#> Ddr2     -3.336392e-03 -0.119776309 -0.100137104 -0.1072134262 -0.0186774712
#> Rspo3     1.431303e-01  0.120579759 -0.012950821  0.0869925988  0.0450280875
#> Arhgap29  1.097046e-01 -0.031582415 -0.231677106 -0.2123062495 -0.0144360578
#> Fzd7      4.812392e-02  0.045110462 -0.031251585  0.0528964049  0.0759748684
#> Slc47a1   2.689901e-02 -0.027593765  0.021204320  0.0133751215  0.0038773672
#> Ptger3   -1.217134e-01  0.107218245 -0.051536892  0.1308241241  0.0220483563
#> Bdkrb1   -1.237338e-01 -0.092245230  0.033552353  0.0570350297 -0.0516797543
#> Traf4     4.195331e-02 -0.053424190  0.019911588  0.0698559999 -0.0369034440
#> Cx3cr1   -1.374479e-01  0.115105459 -0.036614082 -0.0230737572  0.0243591138
#> Anxa11   -1.211922e-01  0.108175113 -0.116850119 -0.0307037486  0.0038767990
#> Adgrb1   -7.540231e-03  0.114818114  0.031592661 -0.0394018280  0.0064328615
#> Lpar1     6.743333e-02  0.036049384  0.130893921 -0.0154479875  0.0364291955
#> Gpr17    -3.424863e-02  0.099316050 -0.073836667 -0.0715334048 -0.0687982666
#> Cxcl12    7.118673e-03  0.078789436 -0.026506266 -0.0165250610  0.0276787455
#> Epha4    -1.077804e-01  0.005086550 -0.023424819 -0.0455338281 -0.0124169517
#> Gpr182   -5.127006e-03 -0.072255659  0.020643640 -0.0844610137  0.0384675086
#> P2ry14   -2.827262e-02 -0.017776785  0.069439084  0.0761260372 -0.0174479531
#> Hcar1     8.245219e-03 -0.169307515 -0.061136870  0.1048085002 -0.0125887689
#> Ephb1     7.933501e-02  0.009227109  0.043837704  0.0663940034  0.0013681269
#> Grm3      1.054366e-01  0.120671946  0.043812672 -0.0605719915 -0.0004615742
#> P2ry1    -1.241989e-01 -0.021344066 -0.015276009 -0.0891443634  0.1655238112
#> Ptk7      3.692229e-02  0.058365021  0.075297973 -0.0905807420 -0.2444265390
#> Slco1a4   3.960095e-02  0.012265630 -0.010000152  0.1347170749 -0.0790255671
#> Insrr     3.303288e-03 -0.056063168 -0.005658957  0.0366097474  0.0985863987
#> Cmklr1   -4.452884e-02 -0.079240285 -0.013233330  0.0314729793 -0.0262771918
#> Fzd6     -7.683884e-02  0.018953054  0.024373600  0.0324010441  0.1798808272
#> S1pr5     3.522360e-02  0.089564115  0.048410357 -0.0149731097 -0.0609867657
#> Pdgfrb    4.186066e-02  0.137317609 -0.149704384  0.1605377461  0.0292368222
#> Flt1     -4.515999e-02  0.079880039 -0.024935392 -0.1129170978 -0.0617926831
#> Adgrl4    2.230768e-02 -0.017956311  0.170414455 -0.1435166252  0.0963468776
#> Lpar6    -2.674174e-02 -0.176404229  0.100057704  0.0626369705  0.0749259054
#> Epha6     7.858181e-02 -0.092516939  0.004377653  0.0306614981 -0.0255877222
#> Emcn     -1.344921e-02  0.023755042 -0.207196493  0.2694192183 -0.0485825614
#> Cldn5    -1.662330e-02 -0.158216302 -0.053101664 -0.1886431748  0.0717726190
#> P2ry12   -1.238912e-02 -0.137329994  0.034529932  0.0091707142  0.0243161908
#> Adgrf5    2.284301e-02 -0.040937827 -0.021443237  0.0466198889 -0.0056802832
#> P2yr13   -1.113402e-02  0.014574959  0.014752478  0.0086699233  0.0154175081
#> Adgre1   -6.912791e-02 -0.026799727  0.018465152 -0.0136996215  0.0878366603
#> Cx3cl1   -2.685946e-02 -0.004512758 -0.013716984  0.0712291447  0.0486563910
#> Plxnb3   -6.405360e-02 -0.149172617 -0.090804014  0.0417755528  0.0114148640
#> Flt4      5.907203e-02 -0.165345418  0.065359515 -0.0580646987  0.0415148139
#> Slc17a7   2.502915e-02 -0.016152172 -0.011883352 -0.0275565058 -0.0649342280
#> Cd300c2  -9.178146e-02  0.146457911 -0.020980943 -0.0800686876  0.0117010951
#> Tek      -1.247060e-01  0.195125143  0.165550610  0.1597793441  0.0460309093
#> Kdr       1.436761e-02  0.013748201  0.043503363  0.2167032530 -0.0962465898
#> Kcnj8     3.780850e-02 -0.025929378  0.059541479 -0.0956904279  0.0526446523
#> S1pr3    -3.972054e-02 -0.086951394 -0.095395602  0.0551027782  0.0617825207
#> Tie1      1.494018e-01  0.104714932 -0.164364053 -0.0279915791 -0.2775782010
#> Pdgfra    3.014636e-02  0.051950432  0.165056354  0.0108871135  0.1149001052
#> Baiap2    8.481868e-02  0.054147008  0.064370961 -0.0088778323  0.0647071059
#> Calcrl   -1.175377e-01  0.074866839  0.063846494  0.2647417594  0.0094264784
#> Adrb2     1.369878e-02  0.028184139  0.007398724 -0.0849416283 -0.0538219816
#> Ccr2     -4.657241e-02 -0.079828485  0.017568886 -0.0839860010 -0.0314660612
#> Alk      -1.205000e-01  0.055750041 -0.031115226 -0.0926035406 -0.0500224877
#> Tacr3    -6.684064e-02  0.115898428  0.045611750 -0.0546322233 -0.0053085325
#> Erbb3    -1.296998e-02  0.129768155 -0.043497459 -0.0888212158 -0.0727856626
#> Pcdh15    2.671940e-02  0.001984140  0.036070622  0.0317228147  0.0873590711
#> Grm7      2.012896e-02 -0.010720198 -0.124076272 -0.0436772126 -0.0242379365
#> F2r      -2.145095e-02 -0.087422879 -0.200238742  0.2059786884 -0.1690432175
#> Bdkrb2    6.887812e-02 -0.011827868  0.124269712  0.1010077276  0.0610755412
#> Adgrv1    1.165612e-01  0.135440541 -0.059904482  0.0960754086 -0.1401058307
#> Gprc5c    6.391407e-02 -0.086733937 -0.080728177  0.0642973633  0.0895423161
#> Tbxa2r   -2.620424e-01 -0.032525551 -0.039874820 -0.0101757904 -0.0547843895
#> Ackr1    -2.547614e-02  0.053859953 -0.047158504  0.1347045621 -0.0575774110
#> Lpar2     3.800211e-02 -0.018605194  0.015109368  0.0438630718 -0.0062211486
#> Myh11     3.661799e-03  0.041543829 -0.011517432 -0.0810440828 -0.0120298574
#> Musk      1.254369e-01 -0.132897852 -0.085905798  0.0486926957 -0.0761179113
#> Cnr1     -6.078101e-02  0.029842763  0.020466309  0.0304315238 -0.0967712847
#> C3ar1     1.584089e-02 -0.146050154 -0.095446285  0.0278511398 -0.1640907807
#> S1pr4     4.631400e-02  0.010700759  0.011934261 -0.1105711788  0.0220394998
#> C5ar1    -1.782270e-02 -0.165383874  0.013860161  0.2538840182  0.1089257050
#> Fpr1     -1.089135e-02 -0.002540849 -0.030889116 -0.0527753640 -0.0560091472
#> Sctr      8.630072e-02  0.028219200  0.054964188 -0.0189475737 -0.0537832914
#> Gpr158    6.188227e-02 -0.055164521 -0.073148122  0.0714465893  0.1435800291
#> Cxcr4    -6.876068e-03 -0.035561742  0.011770111  0.0233199208  0.0643347245
#> Hrh2     -4.839773e-02  0.148475076 -0.203035365 -0.0343350389  0.2645500263
#> Slc17a6  -4.883941e-02 -0.009926849 -0.019351003 -0.0292647483 -0.0139834019
#> Ppp1r3g  -1.246256e-02  0.120582253  0.028793909  0.0059616133  0.0109484360
#> Pln      -4.313203e-03  0.053020230  0.050700097 -0.0391119953  0.0283814353
#> Grin2b   -2.498571e-02  0.016206301 -0.044238756  0.0074485686  0.0857301576
#> Taar7e   -4.859692e-02 -0.108048783 -0.108460696 -0.0561999077 -0.0196165702
#> Ptger2   -1.162974e-01  0.057366116 -0.249926227  0.0827042048  0.1736190167
#> Mc4r      1.149901e-02  0.245347709  0.239972113  0.0903362531  0.0432158993
#> Ghsr      1.223699e-02 -0.026448389 -0.008868179  0.0143234793 -0.0170332587
#> Nmbr     -3.516158e-05 -0.085034858 -0.006184928  0.0429620993 -0.0695392364
#>                 Dim.51        Dim.52       Dim.53        Dim.54        Dim.55
#> Mlc1      0.0864147797  0.0386775355 -0.133413111  0.0380473547 -0.1102939152
#> Gprc5b    0.0357622186  0.0512881874 -0.068807439 -0.0481835083 -0.0437332137
#> Gfap     -0.0217852383  0.0431115841  0.009178273 -0.0011945001  0.0040812457
#> Ednrb     0.1087725419 -0.0808638138 -0.071338394  0.0744174277 -0.0570105994
#> Sox9     -0.0176324689 -0.0826078232  0.152889225 -0.0917811558  0.0779147201
#> Aqp4     -0.0203445968 -0.0488174547 -0.016860661 -0.1032182345 -0.0363172386
#> Gjc3      0.1275113456 -0.0483121278 -0.019414639  0.1850497168  0.0011071938
#> Sox8     -0.1224535096 -0.1750904596  0.026583489  0.0173817150 -0.2252728971
#> Ntsr2     0.0140366587  0.0246952728  0.078319518 -0.0935201998  0.1169457543
#> Smo      -0.1031320026 -0.0359235598 -0.133693345  0.2038910383  0.1063444765
#> C1qb      0.0521542841  0.0094092029  0.002476313 -0.0246306159  0.0789103045
#> Olig1     0.0632934579  0.1449316489 -0.041198344  0.0611857623  0.0209697656
#> C1qa     -0.0656778650 -0.0254267826 -0.010955781 -0.0322721651  0.0374617121
#> Pth1r     0.0043895416 -0.0242733733  0.043880080 -0.0091430761 -0.0828741787
#> Gabbr2   -0.1374284613  0.1593460484 -0.059018276 -0.0275923685 -0.0399142930
#> Timp4    -0.0372242762  0.0271928268 -0.046978817  0.0956635701  0.0298385358
#> Abcc9    -0.0097259150  0.0314977534 -0.059431355  0.0274230190 -0.0052770571
#> Csf1r     0.0365952849 -0.0530367985 -0.072551262 -0.1872273090  0.0377306235
#> Ntrk2    -0.0194439843  0.0458547563 -0.048510111 -0.0597154606  0.0962834845
#> Adgrg1    0.0537804033  0.0166895477 -0.177489015  0.0122632813 -0.0093721989
#> Ntrk3    -0.0107225687  0.1100880625  0.014048952  0.0036945658  0.0791101853
#> Erbb4    -0.0440979329 -0.0123564634  0.039606601  0.0756432951 -0.0160496844
#> Selplg    0.0365344378 -0.0346125185 -0.132803428  0.1123293706 -0.0386259852
#> Cspg5     0.0517471169  0.0396240554  0.097696563  0.0373313387 -0.0593615155
#> Dlk1      0.0124225637 -0.0393928657  0.007115968 -0.0081002040  0.0062991755
#> Gpr37l1  -0.1375541205 -0.1426914677 -0.060408516  0.0049487567 -0.0002983586
#> Fgfr3     0.0704441310  0.0585355837 -0.005745559  0.1263525434 -0.1804427983
#> Slc25a18  0.1478459139 -0.0337286097 -0.052206896  0.0031981546  0.0202625142
#> Igf1r    -0.0676919148  0.2215479203  0.061604277 -0.1322078028 -0.0126485227
#> S1pr1     0.0217424181  0.0562988675  0.128672369 -0.0469290099 -0.0317916341
#> Grm5      0.1267232607 -0.1821298370  0.052846292  0.0424923720  0.0076355397
#> Axl      -0.0266549669 -0.0821029583  0.157901071  0.1279416129  0.0841713056
#> Efemp1    0.0433298740  0.0100590464  0.041090086  0.1147784825 -0.0637470063
#> Adgrb3    0.0340548251 -0.1994057731 -0.051887088 -0.0113294532 -0.0464800559
#> Fn1      -0.0349162454 -0.0401352883  0.048224773  0.0975955940  0.0997022949
#> Mertk    -0.1276267847  0.0775079185 -0.288190844  0.0569550685  0.0789090251
#> Adgrl2   -0.0241442306  0.0409112631 -0.096203450  0.1597259033  0.2413268814
#> Fzd2     -0.0419992850 -0.0180222553  0.022547760  0.0522350728 -0.1547725775
#> Aldh1l1   0.0422315537 -0.0231634494  0.034038794  0.1446442523  0.0158639102
#> Adgrg6   -0.0717403643 -0.0676177911  0.148759259 -0.0519620856  0.0842916639
#> Egfr      0.0284834388  0.0211036995  0.036558208 -0.1104781039  0.0106323406
#> Kit      -0.1765353989  0.0376083486  0.021545916 -0.0218771945 -0.0990823513
#> Ptgdr     0.0148796399 -0.0376569535  0.050108165  0.0071623126  0.1663118745
#> Gad1     -0.0541977029 -0.0163372119 -0.042973321 -0.0069105205  0.0047448288
#> Tyro3    -0.0569203364  0.0612726675  0.076203210 -0.0103244686  0.1607574988
#> Atp13a5   0.0113448248 -0.0653265478 -0.020052422  0.0191948702  0.0960118564
#> Ddr2      0.1681851656  0.0887515342 -0.052155085 -0.1562335324 -0.1977053642
#> Rspo3     0.0761000666  0.0035596410 -0.139773838  0.0350979016 -0.0044469695
#> Arhgap29  0.1667256161 -0.0773465523  0.093483749 -0.1120105349  0.0800865191
#> Fzd7      0.0391600922 -0.0131202374  0.180511473  0.0186110798 -0.0531900152
#> Slc47a1  -0.0121339774  0.0097956856 -0.055939685 -0.1478033048 -0.0290117398
#> Ptger3   -0.1227445202 -0.0024991875  0.030960076  0.1176523492  0.0523231574
#> Bdkrb1   -0.0563752401 -0.0242625363 -0.087956660 -0.0940087552 -0.0667586016
#> Traf4    -0.0111792112 -0.0426464501 -0.050267124 -0.0376267512 -0.0430799491
#> Cx3cr1   -0.1162055761 -0.0069438933 -0.028212431  0.2117797684 -0.0446537063
#> Anxa11    0.0353237978  0.1567190027 -0.054605970  0.1923689361 -0.0701103530
#> Adgrb1    0.0516243637 -0.0522654985  0.071080233 -0.0161336593  0.0100539573
#> Lpar1    -0.1384795678  0.0768995198 -0.144919035 -0.2200563502 -0.0663261050
#> Gpr17    -0.0746612602  0.0197536996  0.047348650 -0.1552907405 -0.0153074045
#> Cxcl12    0.0648913479 -0.0195018206 -0.026275858 -0.0723587833 -0.0564373482
#> Epha4    -0.0843040721 -0.0892352884  0.070502520 -0.0443669373 -0.0984616705
#> Gpr182   -0.0667528492  0.0433835251 -0.018812028 -0.0795079381  0.0061116662
#> P2ry14   -0.0449297426  0.0001195871  0.041216992 -0.0290320869 -0.0599709389
#> Hcar1    -0.1029181773 -0.1187874358 -0.146846265 -0.0006462698 -0.0039605024
#> Ephb1    -0.0616231277 -0.0751957167  0.035772510  0.0283280176 -0.1165143517
#> Grm3     -0.1007750989 -0.0433463680  0.135596165 -0.2009154012  0.1526114637
#> P2ry1     0.0233721854 -0.0638652285  0.016604629  0.0815173824  0.2315074879
#> Ptk7      0.0551579326  0.0445516383 -0.030319575  0.1172336511  0.0345609210
#> Slco1a4  -0.0087573577  0.0269395471  0.009395579 -0.1086067520  0.0605262607
#> Insrr     0.1270950449  0.0333949654  0.028659257  0.0734937210 -0.0372920581
#> Cmklr1    0.0344742592 -0.0113610834  0.013208863 -0.1708795430  0.0564534510
#> Fzd6     -0.0480376453  0.0350960455  0.126015787 -0.0412247023 -0.1663803009
#> S1pr5    -0.0582889903 -0.1316655993  0.012547598 -0.1397729434 -0.0412782701
#> Pdgfrb    0.0553378559  0.0080545505  0.112178670  0.0565945132 -0.1531415817
#> Flt1     -0.0775316321  0.0033952380 -0.061223744  0.0375820168 -0.0100047921
#> Adgrl4   -0.0081703643 -0.0834951982 -0.070501790 -0.0046751832 -0.0808977607
#> Lpar6     0.1223878463  0.0904897121  0.021726169 -0.1141456456 -0.0238123549
#> Epha6    -0.1143417531 -0.1650457045  0.038605281  0.0363261512  0.1822764977
#> Emcn     -0.0386266207  0.0852658395  0.038754419 -0.0403708596  0.0141791906
#> Cldn5     0.1123573616  0.0005760496 -0.018919683  0.0838494382 -0.0193509681
#> P2ry12    0.0229225179  0.0271101977  0.248601936 -0.0514222400 -0.0730620449
#> Adgrf5    0.0353231917 -0.0305784655 -0.012003946 -0.0538631125  0.0138152743
#> P2yr13    0.0270066085 -0.0380045514  0.070438540 -0.0439513987 -0.0244272732
#> Adgre1    0.0166776146  0.0691432729  0.067586534  0.0852109952 -0.0388432612
#> Cx3cl1   -0.0709108140 -0.1656054901 -0.005206945  0.0076716132  0.0551430461
#> Plxnb3    0.1009669067  0.0442974416  0.073272872 -0.0135246931  0.0790419632
#> Flt4      0.1086011493 -0.0605052837 -0.081719541  0.1028148958 -0.1342517212
#> Slc17a7   0.0808908105  0.0051317339  0.042305490  0.0567588205 -0.0031208272
#> Cd300c2   0.0183229148  0.0463674993 -0.252995102 -0.0309029261 -0.0998193754
#> Tek      -0.0551530251 -0.0582152041  0.233546927  0.0202078696  0.0123374170
#> Kdr      -0.1234118278 -0.0380859398 -0.039075774 -0.1609766667  0.1003331397
#> Kcnj8    -0.0103127285  0.0090620487  0.038700421 -0.0007958727 -0.0718108080
#> S1pr3    -0.0179677873  0.0380877212 -0.113772651  0.0039253432  0.0231778531
#> Tie1      0.0789047663 -0.1362516867 -0.039528137  0.1252079846  0.0525015330
#> Pdgfra    0.1019353138 -0.0312812942  0.003423582  0.0652608374  0.0743515118
#> Baiap2    0.1135912593  0.0219881411 -0.196006178 -0.1041168499 -0.0063890775
#> Calcrl   -0.0500724961 -0.0178709405  0.094389259  0.0691643926 -0.1170290672
#> Adrb2    -0.0595874908 -0.0390308949  0.144321534  0.1129875063 -0.0433099847
#> Ccr2      0.0654393950  0.0474509109  0.101245875 -0.0163764868 -0.0554918076
#> Alk       0.0442256589  0.0983084350 -0.040820285 -0.0361424587 -0.0345972165
#> Tacr3     0.1237807279  0.0658279984 -0.006089670 -0.0185418645  0.0645658705
#> Erbb3    -0.0340301323 -0.0390831253 -0.037639453 -0.0582994065 -0.0701854955
#> Pcdh15   -0.0374600639 -0.0224354030 -0.019501705 -0.0307194305  0.0861771739
#> Grm7     -0.1031227969  0.3295882376  0.118844898  0.0816743708 -0.1236703326
#> F2r       0.0931193789 -0.0836869052 -0.072068031  0.0333319191  0.1457884560
#> Bdkrb2    0.1627554070  0.0323463867 -0.054462392 -0.0971855631  0.0458285246
#> Adgrv1    0.0326083983  0.0377132153  0.037772805  0.0637532060 -0.1303758168
#> Gprc5c    0.0285250798 -0.0342096719 -0.056161499  0.0352883874  0.0546336930
#> Tbxa2r   -0.0233685859 -0.0140499300 -0.110105667 -0.0845488830  0.0240069920
#> Ackr1    -0.1012257854  0.1453868666 -0.204118822 -0.1431468391 -0.0383348973
#> Lpar2     0.0507513654  0.0161347153 -0.008616978 -0.0374190895 -0.0061587505
#> Myh11    -0.0155853017 -0.0046230824 -0.093167296  0.0473299380 -0.0628617684
#> Musk     -0.2221807449 -0.0659729925  0.022494216  0.0643440995 -0.1329958905
#> Cnr1      0.1975243417  0.0187672712 -0.018177801  0.0053602430  0.0616084661
#> C3ar1    -0.0381349950 -0.0744630426  0.069071944 -0.0494524922 -0.0451792090
#> S1pr4    -0.0419322910  0.0252769481  0.068791113 -0.0812493796  0.0012319352
#> C5ar1     0.0316802085  0.0356658521  0.122734759  0.0562466352 -0.0950808980
#> Fpr1     -0.0447367180 -0.0402554942  0.030249584 -0.0404073607  0.1518325236
#> Sctr      0.0005447204 -0.0305494889 -0.038582735  0.0843803157 -0.1776756301
#> Gpr158   -0.0341123742 -0.2321943439 -0.068175887 -0.0468304160 -0.0669802745
#> Cxcr4     0.0388084855 -0.0091183998  0.050108364  0.0228397673  0.0069202841
#> Hrh2      0.1102837536 -0.4622618107 -0.083352128 -0.1182196817 -0.2069093626
#> Slc17a6   0.0508423015 -0.0074970378  0.023322623 -0.0106506421  0.0541894186
#> Ppp1r3g  -0.0049939163  0.0635975777 -0.029785943  0.0447019980  0.0430259291
#> Pln      -0.0184412729 -0.0096171260  0.082225912 -0.0304172113 -0.1192326741
#> Grin2b    0.0246089221  0.0405930431 -0.005237479 -0.0605258111 -0.0156904103
#> Taar7e   -0.1608751357  0.0471814613  0.010069119  0.0267038913  0.0625994078
#> Ptger2   -0.0328753449 -0.0262785831  0.014433540 -0.0301211417  0.0668181404
#> Mc4r      0.3421843377  0.0888456847  0.074044448 -0.1326400789 -0.0619409513
#> Ghsr     -0.0176841854  0.0245916486 -0.038920106 -0.1558940969  0.0005784895
#> Nmbr      0.2825238073 -0.0171862648  0.014508438 -0.0115176735  0.1321641075
#>                 Dim.56        Dim.57        Dim.58        Dim.59       Dim.60
#> Mlc1      0.0125631175 -0.1258394688  0.0812768551 -0.0325152883  0.031562163
#> Gprc5b   -0.0305652385 -0.1085300649  0.1563698599  0.0231201457  0.070045161
#> Gfap      0.0021355509  0.0714058083  0.0763472244  0.0650322037  0.025693299
#> Ednrb     0.0584635092 -0.0767763288  0.0033938626  0.0378251709  0.066705871
#> Sox9      0.0805272566  0.0447301351 -0.0421526508 -0.1616761853 -0.159880316
#> Aqp4      0.0037243270 -0.0993403374 -0.2890032234 -0.0982454411  0.016497111
#> Gjc3      0.0101608573 -0.0619153596 -0.1513878036  0.0363212652 -0.110972943
#> Sox8     -0.0809782644 -0.2348320443  0.1566087641 -0.1970185600  0.009194735
#> Ntsr2     0.0389614486  0.1332368717  0.0042891304  0.0609521324 -0.016232585
#> Smo       0.1625453672 -0.0931763845  0.1032452338 -0.1873871441 -0.093587081
#> C1qb     -0.0288261215 -0.0201602299 -0.0335959487 -0.0114946500 -0.017538837
#> Olig1     0.0371927417  0.1044543073  0.0352491176 -0.0223503292 -0.049835683
#> C1qa      0.0184349063 -0.1299580747 -0.0968623043 -0.0704076438  0.102272300
#> Pth1r    -0.0190940473 -0.0458870239 -0.0230064508 -0.1267705292  0.025322508
#> Gabbr2    0.1279993443 -0.0819635234  0.0471205739  0.2377004740 -0.253864197
#> Timp4    -0.0103226545  0.0003300398  0.0331626903  0.1600166279  0.029633641
#> Abcc9     0.0127921714  0.1019249124  0.0798386143  0.1099444579 -0.047089993
#> Csf1r     0.0947957477  0.0616803037  0.0983375044 -0.0100382598 -0.024199670
#> Ntrk2     0.0540820596 -0.1076362312  0.0772730011 -0.1136272052 -0.090542287
#> Adgrg1   -0.2011991797  0.1105710216  0.1585851668  0.0814053222  0.002502263
#> Ntrk3     0.0342178396 -0.0922025185  0.0889694032 -0.0793067495 -0.040569347
#> Erbb4    -0.1127841244  0.1241517211  0.0243371267 -0.1387311268  0.003192089
#> Selplg    0.0056001049  0.0113088113  0.0617843140  0.0609322583  0.058498494
#> Cspg5    -0.1066170764  0.1051521321 -0.1719944945  0.0410005258  0.169845449
#> Dlk1     -0.0234520433 -0.0789734466  0.0812137717  0.0552190654  0.088636265
#> Gpr37l1   0.0115143322 -0.0563338750 -0.0050629521  0.0208197517 -0.103656551
#> Fgfr3     0.0512952728  0.0497756409  0.0732161680  0.0359611281  0.031370725
#> Slc25a18 -0.0364136515 -0.0352914382 -0.0115305289  0.1338703486  0.092329169
#> Igf1r    -0.1892876039 -0.0229877867  0.0257016685  0.1801316021 -0.016640364
#> S1pr1     0.1306441830  0.0018101914  0.0274789829 -0.0270158147  0.004429182
#> Grm5     -0.1368760458  0.1791687318 -0.1323974260 -0.1712051647  0.007993431
#> Axl       0.0080953078  0.1027457305 -0.0555705393  0.0558114128 -0.012201843
#> Efemp1   -0.0038693103 -0.0194672109 -0.0292948458  0.0015103619 -0.009499639
#> Adgrb3    0.0418865733  0.0876056078  0.0469282415 -0.0553319753 -0.028042824
#> Fn1      -0.0897428651 -0.0093729182  0.0532934136  0.1546065148  0.073347073
#> Mertk    -0.0428843560  0.0632799155  0.0225563024 -0.1080896706 -0.083921518
#> Adgrl2    0.0117531844 -0.1089285547 -0.0845206599 -0.0329888054  0.024433420
#> Fzd2      0.0156058562  0.2045668585 -0.0374698440 -0.0113486596  0.040327474
#> Aldh1l1  -0.2382201172  0.0128442191  0.0331049428 -0.0374622942 -0.003951492
#> Adgrg6    0.0474139284  0.0184103792 -0.0454821975  0.1156513958  0.066673811
#> Egfr     -0.1069417753 -0.0812671785 -0.0024913128 -0.0072973791 -0.122554489
#> Kit       0.0300642257 -0.0327735101  0.0267065298  0.1065209672  0.025192545
#> Ptgdr    -0.0125397577 -0.0361986382  0.0673530004 -0.0020460572 -0.115916877
#> Gad1      0.0284670439 -0.0464764177 -0.0098412840  0.0544587438  0.060824305
#> Tyro3    -0.1453580209  0.1799962090  0.0752516138 -0.1401475299 -0.025668316
#> Atp13a5   0.1384154615 -0.0586404260 -0.0577130317  0.0174343417  0.006329030
#> Ddr2      0.0155556273  0.0329578665 -0.1493021151 -0.0471333999 -0.006488838
#> Rspo3     0.1616813769  0.0365731059  0.0149345127 -0.0392573731  0.115983276
#> Arhgap29  0.1680927605  0.0079360302  0.1528593729 -0.0222403790 -0.130187594
#> Fzd7      0.0011474288 -0.3060422598  0.0584027983 -0.1677444767  0.022086315
#> Slc47a1  -0.0014693147  0.0327199581 -0.0303133683 -0.0562508697 -0.012478167
#> Ptger3    0.0025240676  0.0807933396 -0.0370147991  0.1870709440  0.026449610
#> Bdkrb1   -0.0054946102  0.0028979903  0.1049069710  0.0207177154  0.244792369
#> Traf4     0.0784828597 -0.0437363600 -0.0738189224  0.0091249010  0.034223995
#> Cx3cr1   -0.0070421751  0.1107192802 -0.0099338258  0.0906263805 -0.025540025
#> Anxa11    0.0279295400 -0.1257517021  0.0385773930 -0.0172069015  0.008509316
#> Adgrb1   -0.0997161699  0.0733953598 -0.1247643052 -0.0680026604  0.123040368
#> Lpar1     0.0024810195  0.0733857149  0.0980163593 -0.1670248625  0.025164236
#> Gpr17    -0.0281835976 -0.0070786767  0.1093938914 -0.0062593664  0.084807261
#> Cxcl12   -0.0205918367 -0.0186568854 -0.1313499570 -0.0362173683  0.065591407
#> Epha4    -0.0882998594  0.0214887514  0.0584114344 -0.0378809914  0.086296819
#> Gpr182   -0.2511028389 -0.1010533342  0.1584131767  0.0759866564 -0.118515215
#> P2ry14   -0.1699238060 -0.0311742208 -0.0810930931  0.0262569617 -0.004472930
#> Hcar1     0.1129573388  0.2409686412 -0.0272745259 -0.0412985034  0.161535440
#> Ephb1     0.0961312701 -0.1512075512 -0.1332085826  0.0929246304  0.091554560
#> Grm3     -0.0437337777 -0.1426346631 -0.0521254244  0.0830198376  0.220799293
#> P2ry1     0.0033777554 -0.0724721100  0.0975151749 -0.0683411033  0.172923042
#> Ptk7      0.0547041952  0.0288532318 -0.2986611777  0.0004828615 -0.155016303
#> Slco1a4  -0.0226297908  0.0337860563  0.0835626158  0.0552278139 -0.165459302
#> Insrr    -0.2437482602  0.0676910275 -0.0780102992  0.0981906440  0.028604828
#> Cmklr1    0.0027984760  0.0086719619  0.0829172848  0.0251346197  0.093161593
#> Fzd6      0.0008739310  0.0235940308  0.0248012771 -0.0825901102 -0.107852996
#> S1pr5     0.0242998373 -0.0273065472  0.0062585725  0.0563690282  0.087205293
#> Pdgfrb    0.0529741275  0.0550393462  0.1198278997 -0.0466095825 -0.029252266
#> Flt1     -0.0986397623 -0.0248673926 -0.1682185910 -0.0347979310 -0.138943493
#> Adgrl4   -0.0433109295  0.0117893302 -0.0717634707 -0.1129017096  0.090181666
#> Lpar6    -0.0659236459 -0.1430136329 -0.0293633463 -0.0277795373 -0.025439290
#> Epha6    -0.1939758161 -0.0343699315  0.0650277523 -0.0893479263 -0.061099359
#> Emcn      0.0495065102 -0.0647088550 -0.0845519180 -0.0093167166 -0.062814480
#> Cldn5     0.0112692681 -0.0160991141 -0.0005573598  0.0446081285  0.169515921
#> P2ry12   -0.0978875638 -0.0492236037 -0.1014475097 -0.0612664767 -0.027145536
#> Adgrf5    0.0752205862  0.0467587796 -0.0148236659 -0.0584500374  0.221630755
#> P2yr13    0.0933062122 -0.0537551669 -0.0219436226 -0.0060993427  0.015400181
#> Adgre1   -0.0099158210 -0.0356890146 -0.0483830547  0.0560885311  0.016669965
#> Cx3cl1   -0.1283467969  0.0980470576 -0.0157475082  0.0216342962 -0.103819901
#> Plxnb3   -0.0130991068 -0.0026998420 -0.0277201108  0.1244705153 -0.024357665
#> Flt4      0.0995414370  0.0028472668 -0.0282088913 -0.1313477633 -0.088914796
#> Slc17a7  -0.0230888467  0.0489992760 -0.0029864940  0.0032591073  0.100060779
#> Cd300c2  -0.0458736418  0.1020948329  0.0983767433 -0.0271564174 -0.043635012
#> Tek       0.2465059035  0.0394645247  0.0940994749  0.0396530885 -0.019712450
#> Kdr      -0.0649951747  0.0812261263 -0.0048572810  0.0271083938 -0.122392433
#> Kcnj8    -0.1014553427  0.0882397342  0.0366640333 -0.0348519591 -0.041307201
#> S1pr3    -0.0902119900 -0.0249242233 -0.0544814138  0.0771760642  0.053455368
#> Tie1     -0.1069020758 -0.0915140356  0.2578190970  0.0134750468  0.033993417
#> Pdgfra    0.0643018899  0.0281471252 -0.0739105961  0.2112805124 -0.041273586
#> Baiap2    0.1104616654 -0.1474351656 -0.0222166970  0.1386394947  0.020071104
#> Calcrl    0.1244032080  0.0365418755  0.0241490890 -0.0537304520 -0.171705872
#> Adrb2    -0.0485114356  0.0123821031  0.0490913193  0.1177803595  0.003030082
#> Ccr2     -0.0608178756 -0.0375105802 -0.0153748349  0.0297278426 -0.063357335
#> Alk      -0.0432839639 -0.0834115848 -0.0841439855 -0.0300399150 -0.027021944
#> Tacr3    -0.0427312328  0.0104073009  0.0184935125  0.0296168255 -0.029295753
#> Erbb3     0.0588699886  0.2054543319  0.0256636591 -0.0818830122 -0.070049261
#> Pcdh15    0.0006348089  0.0636586879 -0.1583186965  0.0142013211 -0.041341955
#> Grm7      0.1661827875  0.0744208850  0.0398764012 -0.0497191080  0.151582905
#> F2r      -0.0014730327 -0.0614655318 -0.0526321999 -0.0541502699  0.007806200
#> Bdkrb2   -0.0575874852 -0.0402068372  0.0397186042 -0.0078895207 -0.132682144
#> Adgrv1   -0.0951414401 -0.1127886005 -0.0350161915  0.0631818594 -0.052376734
#> Gprc5c    0.0047510536  0.0459720328 -0.0499402543 -0.1094925677  0.016724648
#> Tbxa2r    0.0666518978 -0.0522195564 -0.1106764446 -0.0737239887  0.111871445
#> Ackr1    -0.1044346039 -0.0377061386 -0.2082417510 -0.0568595862 -0.002542482
#> Lpar2    -0.0362003732  0.1112685866  0.0104502969  0.0225967070  0.131476991
#> Myh11    -0.0941300214 -0.0225495709 -0.0980065710 -0.0302217744 -0.105998619
#> Musk     -0.0211486737 -0.0259382155 -0.0295046770 -0.0114267884 -0.008274967
#> Cnr1      0.0632683129 -0.0035031760  0.0319345247 -0.0468717278 -0.048588307
#> C3ar1     0.0929069437  0.1297420031  0.0669043167  0.0787876501 -0.032815816
#> S1pr4     0.0128334673  0.0216923945 -0.1612809445  0.0144505534 -0.101883147
#> C5ar1    -0.0499523644 -0.1436311727  0.0870690367 -0.0836865760 -0.020422608
#> Fpr1      0.0791205054  0.0360995729 -0.0218960276  0.0328010364  0.015369955
#> Sctr     -0.0515800467  0.0467266061  0.0524115513  0.0469323465 -0.071430313
#> Gpr158   -0.0007208232 -0.0261546051  0.0082102851  0.0925688954  0.138652309
#> Cxcr4     0.0143479027  0.0340470151  0.0416501285 -0.0382331341  0.020915839
#> Hrh2     -0.0044647236 -0.0908611357 -0.0138365251  0.2488935041 -0.199251703
#> Slc17a6   0.0151548519  0.0369575062  0.0173631601  0.0034547619 -0.002517079
#> Ppp1r3g  -0.0405298481 -0.1222379604 -0.0346799352  0.0700405209  0.118079841
#> Pln       0.0748123078  0.0483826517 -0.0389908657 -0.0116775316 -0.005489177
#> Grin2b    0.0792476734 -0.0157385827 -0.0001124593  0.2310324967 -0.024981003
#> Taar7e    0.0644724481 -0.1096456877 -0.0059358117 -0.0317436310  0.013958289
#> Ptger2   -0.1258876980 -0.0501821138  0.0072855899 -0.0695578612  0.006726419
#> Mc4r     -0.0811609986  0.1272446124  0.1350917084 -0.0333871203  0.039833203
#> Ghsr      0.0876575950  0.0571697380 -0.0141473440  0.0578700676 -0.073276938
#> Nmbr      0.0750855237 -0.0243946563 -0.0134219369 -0.0729800023 -0.049924914
#>                 Dim.61        Dim.62        Dim.63       Dim.64        Dim.65
#> Mlc1     -0.0363434655 -0.1547949294  0.0690070544  0.120829101  2.312221e-01
#> Gprc5b    0.0362279509  0.0175050913  0.0905423914  0.014155961  8.418026e-02
#> Gfap     -0.0363755013 -0.0259665488 -0.0352573003  0.007087687 -4.463271e-02
#> Ednrb     0.0713049646  0.0933871364  0.0034181948  0.061534550 -7.867310e-03
#> Sox9      0.1701790493 -0.1457135747  0.1292493435 -0.161085744  2.435420e-02
#> Aqp4      0.0609575050  0.0622959430  0.0819136872 -0.087797690  1.548329e-01
#> Gjc3      0.0507582735 -0.0633504472 -0.0534559136  0.148344015  2.691779e-02
#> Sox8     -0.1511520915 -0.1050312649 -0.0178710295  0.023132844  2.683183e-02
#> Ntsr2    -0.0086247569 -0.0831650661 -0.0577663979  0.013954495  6.752734e-02
#> Smo      -0.0625214729 -0.0251252897  0.1275467246  0.138555843  2.784213e-02
#> C1qb     -0.0690887292 -0.0793736673  0.0510743038  0.150138335 -6.531145e-02
#> Olig1    -0.0369556045 -0.0069395097  0.0357138555 -0.140644311 -1.168722e-01
#> C1qa     -0.0187377855 -0.0244912115  0.0423976662 -0.051603049  6.670225e-04
#> Pth1r     0.0028351836  0.1058943534 -0.0409482964  0.036792352 -3.652917e-02
#> Gabbr2   -0.1162459705  0.1024793225  0.0029229914 -0.187797538  1.337037e-01
#> Timp4     0.0350464414  0.0329134652  0.0198732126  0.078165490  7.515997e-02
#> Abcc9     0.0761818642 -0.0410427203 -0.0113425588 -0.011964967  8.140403e-02
#> Csf1r    -0.1169059544  0.0771002961 -0.0225656742  0.054377017  1.765171e-01
#> Ntrk2    -0.0283888316  0.0484163434 -0.0428191822  0.088102580  2.805628e-02
#> Adgrg1    0.0392042591 -0.0906504241 -0.0653489655  0.042012621 -1.912321e-03
#> Ntrk3    -0.0013109246  0.0919907867 -0.1405054212 -0.071662132  7.280188e-02
#> Erbb4    -0.0132933634  0.0697890303  0.0512855728  0.104244028 -2.272039e-02
#> Selplg   -0.0885546636  0.0075408374  0.0268323459 -0.083826466  1.102152e-01
#> Cspg5     0.0145335597 -0.0522911210 -0.2276891360  0.027749113  7.355342e-03
#> Dlk1     -0.0585290783  0.1067931285 -0.0523287905  0.076587946 -8.788101e-02
#> Gpr37l1   0.0117530280  0.0567440375  0.1439278622 -0.088012784 -6.130192e-02
#> Fgfr3    -0.0702296226  0.0171812419  0.0581130944  0.066354233 -4.197903e-02
#> Slc25a18 -0.2102427413  0.2908783066  0.0928012716 -0.025961975 -1.695964e-01
#> Igf1r     0.0517043270 -0.1226090440  0.0168146348 -0.123404477 -1.077369e-01
#> S1pr1    -0.0816224861  0.0480052674 -0.0131399092 -0.037457685 -3.773583e-02
#> Grm5     -0.0300549804  0.0519683454  0.0575651156  0.050933926 -5.897599e-02
#> Axl       0.1635970644 -0.0978900111  0.0398933074  0.025567917 -5.145290e-02
#> Efemp1    0.0726508638  0.1016542543 -0.0614805003  0.014794407 -4.386747e-02
#> Adgrb3    0.1470858854 -0.0073336295 -0.0383271997 -0.065662739  8.932871e-02
#> Fn1      -0.1058294678 -0.0347351444  0.0207403748 -0.042515046  7.406163e-02
#> Mertk     0.0749844751  0.0571316367 -0.0171342954 -0.097561389 -1.733548e-01
#> Adgrl2   -0.0907134060 -0.1606302540 -0.0666785154 -0.038661246  3.070973e-02
#> Fzd2     -0.1395293382 -0.0559231309  0.0494726955 -0.135529819 -7.924828e-02
#> Aldh1l1  -0.0629451618 -0.1819791270 -0.3694097086  0.143497760 -3.546132e-02
#> Adgrg6   -0.1256371143  0.0360689842  0.1123032643  0.061291551 -1.050019e-01
#> Egfr     -0.0394857889  0.0288213323  0.1025090990  0.131267359 -1.798244e-01
#> Kit       0.0527135237  0.0296577131 -0.0724540051  0.017279987  1.479790e-02
#> Ptgdr     0.0084029918  0.0449752574  0.0094437808  0.081641587  6.026343e-02
#> Gad1      0.0045208390 -0.0203915408  0.0270705051 -0.063888453  3.795085e-02
#> Tyro3     0.0210221152  0.1052458845 -0.0150436166 -0.230928268 -3.541155e-02
#> Atp13a5   0.0446350024 -0.0906449940  0.0413781117 -0.008833788 -6.372984e-02
#> Ddr2      0.0546973860  0.1270878853  0.0054824872  0.088908891  2.441886e-02
#> Rspo3     0.1051182550  0.0320527931 -0.1020131912  0.049037703  6.075154e-02
#> Arhgap29  0.1589068947  0.1498024091 -0.0145526341  0.072643870 -4.978069e-02
#> Fzd7     -0.0185937818 -0.1644659693  0.0270833690 -0.061888287 -6.079709e-02
#> Slc47a1  -0.0508272483 -0.1030855685 -0.0060520438  0.017414978 -1.597815e-03
#> Ptger3   -0.0584433835  0.0294209687 -0.0817687826  0.011122160 -1.180247e-02
#> Bdkrb1    0.1816189771 -0.0094979873  0.1344661849  0.022435704 -1.301310e-01
#> Traf4     0.0665581800  0.0927689433 -0.0798955499  0.003978262  1.022135e-01
#> Cx3cr1    0.1233298588 -0.0202978330  0.0433191507  0.052033919 -2.997915e-02
#> Anxa11    0.0513003949  0.0323658764  0.0162963529 -0.009965616  3.153566e-02
#> Adgrb1   -0.0095715520  0.0601539994  0.0447904115 -0.055503417  1.346521e-01
#> Lpar1     0.0005013196  0.0181735025 -0.0536482226 -0.094870360 -1.450974e-01
#> Gpr17    -0.0467366713  0.0228362735  0.0797881897  0.018781938 -3.504827e-02
#> Cxcl12   -0.0804436914 -0.0525400551 -0.0031925270 -0.054069448  2.537165e-02
#> Epha4     0.1094037039 -0.1487513500  0.1270004458 -0.072452626 -3.484660e-02
#> Gpr182   -0.0033164079 -0.0149051188  0.0422184199  0.027191957  1.812753e-05
#> P2ry14    0.0077978961 -0.0339643140  0.0291564542 -0.053040744  1.054677e-01
#> Hcar1     0.1479011252 -0.0320484046  0.0354660553 -0.009629197  8.073636e-02
#> Ephb1     0.2143238400  0.0575415770  0.3121813814 -0.036390674 -9.131967e-02
#> Grm3     -0.0735233943 -0.0074907482 -0.0401411464  0.052211165  1.398112e-01
#> P2ry1     0.0419996193 -0.0555842984  0.0004363337 -0.056879141 -3.276266e-02
#> Ptk7     -0.2107969559 -0.0048060099  0.0123056527 -0.204726002 -8.022361e-02
#> Slco1a4   0.1147361423 -0.0756270772 -0.0436023380  0.096026886 -5.075217e-02
#> Insrr    -0.1172753250  0.0424788927  0.0820528921  0.023949188  1.144644e-01
#> Cmklr1   -0.0396041090  0.0136026580  0.0010788041  0.024602600  9.070060e-02
#> Fzd6     -0.1140211764  0.1530751429 -0.0697895657  0.113688375  9.875577e-02
#> S1pr5    -0.0660805937  0.1080812139  0.0046660077  0.030912316  1.341179e-02
#> Pdgfrb   -0.0732461491  0.1501492812 -0.0527445960 -0.047087757 -2.850070e-03
#> Flt1     -0.0155193272  0.0266518562  0.0673163402  0.094393292 -1.011798e-01
#> Adgrl4   -0.0346288260  0.0425105213 -0.0108792787 -0.009631311  1.770198e-01
#> Lpar6    -0.0588805058  0.0571018410  0.0483397106  0.050578808 -6.025791e-02
#> Epha6     0.1555536626  0.2430613926 -0.1852991630 -0.029631591  1.834738e-01
#> Emcn     -0.0305888355  0.0959423664 -0.1325424252 -0.123799242 -2.558188e-02
#> Cldn5    -0.0067321275  0.0122745704  0.0127934315 -0.085871309  5.538852e-02
#> P2ry12    0.1154826304 -0.0150175459 -0.0742144472  0.019093224 -1.626320e-01
#> Adgrf5   -0.0521902166  0.0320573870 -0.0207656274 -0.063117020  1.082515e-01
#> P2yr13    0.0339352881  0.0244972272 -0.0700270533 -0.145165307  8.854780e-02
#> Adgre1    0.1423820803  0.0869281922 -0.1034038317 -0.134396462 -4.992566e-02
#> Cx3cl1   -0.0546487691  0.1214932329  0.1470428951  0.172273146  4.498589e-02
#> Plxnb3    0.0549917780 -0.1360321683  0.0950419678 -0.066517875  1.400429e-01
#> Flt4      0.1198038368 -0.0217541494 -0.0295915995  0.003615632 -6.545003e-02
#> Slc17a7  -0.1040082909 -0.0544688558  0.1011107378  0.074855289 -3.432861e-02
#> Cd300c2  -0.0852420058  0.1236184937  0.0134183798 -0.021155570  2.728315e-02
#> Tek      -0.0482992317  0.0257313910 -0.0542945457 -0.037682356 -1.068850e-01
#> Kdr       0.1058664750 -0.1358585739  0.0403373051  0.181343131  3.036184e-02
#> Kcnj8    -0.0344877640  0.0163157234  0.0543891824  0.007888845  1.081797e-01
#> S1pr3    -0.0452942301 -0.0690724372  0.0166450601 -0.039199798 -1.201898e-01
#> Tie1      0.0844206796  0.0122081981  0.0943294026 -0.169360972 -1.482741e-01
#> Pdgfra   -0.0039157415  0.0876653809  0.0170881633  0.105164240  8.138765e-02
#> Baiap2    0.0334069736 -0.0659063688 -0.2514798559 -0.073928874 -1.306925e-01
#> Calcrl   -0.0795227061 -0.0702647992 -0.0283846237  0.160238947  5.060292e-02
#> Adrb2    -0.0608379472  0.0165235825 -0.0087501827 -0.043961970  6.355782e-02
#> Ccr2      0.0450320033  0.0201140813 -0.0817428718 -0.043632859 -2.042879e-02
#> Alk       0.0193764339  0.0129192361 -0.0440073469  0.082974022 -1.287248e-02
#> Tacr3     0.1332178273  0.0295397648  0.0777628377  0.026480596  3.395530e-02
#> Erbb3    -0.0567245023  0.0240321500 -0.0815180039 -0.006732310  9.438577e-03
#> Pcdh15    0.1906372756 -0.0610292243 -0.0448330055 -0.050284579  2.352267e-02
#> Grm7      0.0193440105 -0.2034341921  0.1329459106  0.191313159  1.325848e-01
#> F2r      -0.1506523811  0.0260753897  0.1440656235  0.033552726  2.891180e-02
#> Bdkrb2    0.1140806165 -0.0002623405  0.0836713590  0.060123821  1.249961e-01
#> Adgrv1    0.2284523889  0.2460625624  0.0494842467 -0.102673594  7.705142e-02
#> Gprc5c   -0.0565288608 -0.1142209865  0.0292548153 -0.118833458  2.911910e-04
#> Tbxa2r    0.0436121427 -0.0561700454 -0.0962430534  0.150360368 -1.478006e-01
#> Ackr1     0.0134996377 -0.0343470921 -0.0174875412 -0.050907786  4.855027e-02
#> Lpar2    -0.0112034563  0.0556131690  0.0485626116 -0.067900980 -2.298362e-02
#> Myh11     0.0794628081  0.0090021298 -0.0031261657  0.076100956 -9.440891e-04
#> Musk     -0.1132664810 -0.0160927527 -0.0139378836 -0.036576131 -4.239191e-02
#> Cnr1     -0.0066558292 -0.0366830708  0.0281410669 -0.004356620  2.028521e-02
#> C3ar1     0.0155008299  0.0166105274 -0.0245486781 -0.006759377  2.784848e-02
#> S1pr4    -0.0220906316  0.0033879640  0.0141870236  0.168667541 -6.699874e-02
#> C5ar1     0.0960111160 -0.0535007413 -0.0743741347 -0.072689203  2.516896e-02
#> Fpr1      0.0329341540  0.0321719135 -0.0596426659  0.006059747 -1.256468e-02
#> Sctr      0.0695576161 -0.0531381936  0.0921986957  0.011224008 -7.011426e-02
#> Gpr158    0.0015329909  0.0548280767 -0.2227016310  0.173174901 -2.903093e-01
#> Cxcr4    -0.0016786406  0.0219833075  0.0414682025 -0.003677807 -2.395059e-03
#> Hrh2     -0.0792255225 -0.2616825076 -0.0718836525 -0.161641011  1.007261e-01
#> Slc17a6  -0.0357243084 -0.0115859619 -0.0387670457  0.050875528  6.262938e-02
#> Ppp1r3g   0.1669086391  0.0811501547 -0.0286354384  0.145831306  8.553946e-02
#> Pln       0.0684256776  0.0694085860 -0.0522243887  0.065296752  5.266343e-02
#> Grin2b    0.0523079210  0.0052384402  0.0947439856  0.100807064 -1.024327e-01
#> Taar7e   -0.0738361372  0.0002086252 -0.0930331693 -0.020204480  5.401002e-02
#> Ptger2   -0.0667717302  0.0788384479  0.2038392132  0.004995610 -1.276164e-02
#> Mc4r      0.0333960736 -0.1396369222 -0.0106242395 -0.079133700  8.469524e-04
#> Ghsr     -0.0693555261 -0.0889129111  0.0880344797  0.014366345 -4.696204e-02
#> Nmbr     -0.0965961547  0.0039125312  0.0420587836 -0.020019142 -1.199213e-01
#>                 Dim.66        Dim.67       Dim.68        Dim.69        Dim.70
#> Mlc1     -2.180444e-02  0.0509485754  0.268830108  0.2073268570  0.1481951292
#> Gprc5b    5.735700e-02  0.2503791817 -0.106428827  0.1776642000 -0.0490134765
#> Gfap     -5.313815e-02 -0.0708074923  0.037384256  0.0016725497 -0.0362639411
#> Ednrb    -7.024608e-03  0.0946853285  0.034493813  0.0576949710 -0.2285982282
#> Sox9      1.807022e-01  0.0546773712  0.070783877 -0.0382300910 -0.1177357502
#> Aqp4      1.592885e-01  0.0329768358 -0.070395176 -0.0248747928  0.0970304244
#> Gjc3     -3.323623e-02 -0.0428932266 -0.097155096  0.0356396823 -0.0362664889
#> Sox8     -5.277059e-02 -0.0702069374 -0.067654032  0.0847521498 -0.1821537499
#> Ntsr2     1.688058e-02 -0.0855470970  0.027037766 -0.0228350509  0.0865575306
#> Smo       9.069631e-02 -0.0999477249  0.015316573 -0.1035136035 -0.0903782692
#> C1qb      6.431639e-02 -0.0236558233 -0.007937257 -0.0208539151 -0.0167829225
#> Olig1     8.167612e-02 -0.0768756932 -0.008059446 -0.0014557578  0.2081991701
#> C1qa     -7.250339e-02 -0.0610496153  0.041596122  0.0134164109  0.0697352462
#> Pth1r    -1.146547e-04  0.1146435822  0.027816673  0.0507767074 -0.0367906224
#> Gabbr2   -9.455405e-02  0.1017963300 -0.011819667 -0.1079435303 -0.0572648210
#> Timp4    -3.103154e-02 -0.0536642920 -0.075443225 -0.0680516985  0.1248819977
#> Abcc9     6.328993e-02  0.0068940021 -0.128888497  0.0248664545 -0.0376274956
#> Csf1r    -3.376456e-02 -0.1376937249  0.060473759  0.0179306420 -0.0185606207
#> Ntrk2    -6.184334e-02  0.0393200132  0.056932403 -0.0378919698  0.1476871517
#> Adgrg1   -5.671942e-02  0.0739760013 -0.056784189  0.0352210481 -0.0878511515
#> Ntrk3    -1.289265e-01  0.0926089226  0.014160283 -0.0855939359 -0.0864180736
#> Erbb4    -6.175009e-02 -0.0719833111  0.039687117 -0.0576475924  0.0276273570
#> Selplg    4.532071e-02 -0.0067639082 -0.069806173  0.0635047704  0.0003958421
#> Cspg5    -9.683195e-02 -0.1085274708 -0.156940211  0.0113932006 -0.1473729815
#> Dlk1     -9.038941e-02  0.0012696048  0.064229827 -0.0637610055 -0.0074678825
#> Gpr37l1   3.819727e-02  0.0278482987 -0.096895834 -0.0523089889  0.0574720748
#> Fgfr3    -1.543647e-01  0.0321129405  0.202431531 -0.0362069394 -0.0014650356
#> Slc25a18  3.852797e-02 -0.1596785085 -0.049197666 -0.0973583053 -0.0251660525
#> Igf1r     9.880276e-02 -0.0274912042  0.069245082  0.0646948662 -0.3308105369
#> S1pr1     3.196872e-02 -0.1341877696  0.182367895  0.0858929441 -0.0704561353
#> Grm5     -1.139508e-01 -0.0324040008 -0.062967961 -0.0596359471 -0.0422567204
#> Axl      -8.913474e-02  0.1042111503  0.096248942 -0.0570438354 -0.0892342835
#> Efemp1    2.237215e-02 -0.0352328527 -0.035873485 -0.0692725147  0.0478291537
#> Adgrb3    8.725996e-02 -0.0252023723  0.034915916 -0.0935292744  0.0627254945
#> Fn1      -1.163542e-01  0.0537656999  0.044686716  0.0810373760  0.0469238872
#> Mertk    -8.647904e-02  0.1210436145 -0.088566619  0.0573608159 -0.0006104242
#> Adgrl2   -2.064289e-03 -0.1157869316  0.047864879 -0.0746061721  0.0125967135
#> Fzd2      1.633771e-01 -0.1050816395 -0.005585715  0.1005945047 -0.0007038798
#> Aldh1l1  -4.863740e-02 -0.1081526474 -0.177888569 -0.0580112239  0.1650436979
#> Adgrg6    7.030933e-02 -0.0393976569  0.070051139 -0.0385737212  0.0380361790
#> Egfr     -1.122364e-01  0.0322319403 -0.014760206  0.1431062119 -0.0302216042
#> Kit      -5.858489e-02 -0.0252964268  0.025001497 -0.0119366782  0.0824318599
#> Ptgdr    -6.424682e-02  0.0878189159 -0.067495526  0.0076604962  0.0461745449
#> Gad1      4.734447e-02  0.0249047951 -0.067107862  0.0450866515  0.0022643001
#> Tyro3     9.807800e-02  0.0569549369  0.143174619 -0.2399856277 -0.0365760436
#> Atp13a5  -2.777914e-02 -0.0928380836  0.075681991 -0.0787949787 -0.0345953792
#> Ddr2      6.543896e-02 -0.0104007773  0.004722769  0.0426247739 -0.0748795891
#> Rspo3     4.291280e-02 -0.1178230258 -0.023212467 -0.2122770140 -0.0918374535
#> Arhgap29  5.550297e-02  0.0366830170 -0.167052644  0.0906459975 -0.0263857205
#> Fzd7      1.863546e-03  0.1070347570  0.115631709 -0.0591066088 -0.0776524979
#> Slc47a1   4.684035e-02 -0.0244283416  0.001303967  0.0608170870  0.0328530568
#> Ptger3   -6.286797e-02  0.0374204689  0.082281266  0.0563592703  0.0591123992
#> Bdkrb1   -9.511756e-02 -0.0942972014 -0.018464926 -0.0993888670  0.0237951108
#> Traf4    -1.149698e-01  0.0545923176  0.040503404 -0.1057209814 -0.0515894468
#> Cx3cr1    4.448548e-02  0.1501238920 -0.012641075 -0.0187385562 -0.0722349627
#> Anxa11    2.646427e-01 -0.2760280374 -0.061635376 -0.1054860528 -0.1362392279
#> Adgrb1   -4.789822e-02  0.0011749307 -0.040811845  0.3008067472  0.0414684839
#> Lpar1    -8.238595e-02 -0.1244296704 -0.063785151 -0.0347945122  0.0845929891
#> Gpr17     2.035282e-02  0.0203824417  0.028740057 -0.0610067861  0.0577816203
#> Cxcl12   -1.468419e-01 -0.0102809200  0.123691090  0.0417879960  0.0581991990
#> Epha4     1.010654e-01 -0.1343726689 -0.136827150  0.1453590870 -0.0766896454
#> Gpr182    5.702545e-02 -0.0369997088 -0.020969974 -0.0647287082  0.1126997056
#> P2ry14   -6.944200e-02  0.0533099636  0.051846358 -0.0416923965  0.1233763291
#> Hcar1    -3.004285e-02  0.0819482274 -0.069177994 -0.0250579826 -0.0863313712
#> Ephb1    -1.421088e-01 -0.0261027951 -0.071937626  0.1863365828  0.2779048367
#> Grm3      1.369024e-01  0.0029764265 -0.018496859 -0.0901648787 -0.0458559239
#> P2ry1    -7.449036e-02  0.0898084448 -0.039822891  0.0508188865 -0.0695922339
#> Ptk7     -8.549627e-02  0.0628703488 -0.062995763  0.1150675458  0.0603093544
#> Slco1a4  -8.244239e-02  0.0009620091 -0.053798546  0.1288775536  0.0187408190
#> Insrr     1.109964e-01  0.1194547260 -0.072473511 -0.0384624547 -0.0525173643
#> Cmklr1    8.287082e-02 -0.0535498217 -0.130034823 -0.0229776114  0.0500126685
#> Fzd6      1.321660e-01  0.0144199643 -0.208261844 -0.0206463307  0.1026324326
#> S1pr5    -3.306042e-02  0.0505443319  0.029651998 -0.0259124538 -0.1753439125
#> Pdgfrb   -9.453916e-02 -0.0430714491  0.038897726  0.0860887076  0.0148144960
#> Flt1      5.291115e-02 -0.0166497237  0.080254244 -0.0311409824  0.0428088617
#> Adgrl4   -2.415542e-05  0.0173469552 -0.082244419 -0.1429460622  0.0572207401
#> Lpar6     1.255938e-05  0.0679932436  0.070519629  0.0044468281 -0.0146509063
#> Epha6     1.158855e-01 -0.1942669820  0.234264801  0.2828944622  0.0425495209
#> Emcn     -9.433091e-02 -0.1458467574  0.005451370  0.0210588089  0.0322306084
#> Cldn5    -3.915228e-02 -0.0315559801  0.127931519 -0.0429383465 -0.0204878394
#> P2ry12   -3.373338e-02  0.0708821012  0.010509976 -0.0687328407  0.0139550011
#> Adgrf5    1.810203e-02  0.0732510684 -0.004878348 -0.0464582832 -0.0190382800
#> P2yr13   -6.614625e-02 -0.1078141268  0.001570643  0.0216281907  0.1539601742
#> Adgre1   -4.179230e-02 -0.0079797822 -0.050419779  0.0082445979  0.0229729075
#> Cx3cl1   -4.625971e-02 -0.0676084560  0.096315663  0.0050563932  0.0765853026
#> Plxnb3    1.749145e-01 -0.0455347819  0.001378771 -0.0049625043  0.0214533419
#> Flt4     -5.657952e-03 -0.0598560645 -0.072707446  0.0655366145 -0.0611033774
#> Slc17a7  -9.659451e-02  0.0985333693 -0.100712126 -0.0972843882  0.0283024070
#> Cd300c2   4.687387e-02  0.0491626576 -0.009755632  0.1019862691 -0.0398527218
#> Tek       3.057949e-02  0.0143083634 -0.267661650  0.1072584158  0.0635469833
#> Kdr      -2.662782e-02  0.0638379380 -0.090074157  0.0037730731 -0.0318037031
#> Kcnj8     2.719719e-02  0.0525318342 -0.027521016 -0.0557996198  0.0574561414
#> S1pr3     2.710308e-02 -0.0415936134  0.051371790  0.0304945807  0.0021683414
#> Tie1     -3.195196e-02  0.0023658947  0.045181223 -0.0131240363  0.1439546487
#> Pdgfra    1.664750e-02  0.0550685589  0.040726360  0.1454141458 -0.1236729211
#> Baiap2    1.802067e-01  0.1307522080 -0.014527508  0.1075417272  0.0841343417
#> Calcrl    1.208724e-01  0.0920428499  0.152312768  0.0113467312 -0.0543336788
#> Adrb2     7.526892e-02  0.0386791434 -0.014336466 -0.0221495165  0.0180708207
#> Ccr2      8.311026e-03  0.0216781648 -0.035463248 -0.0201927133  0.0268575194
#> Alk       8.424806e-02 -0.0171405303  0.037199497 -0.0337643015 -0.0291163607
#> Tacr3    -4.318870e-02 -0.1983578007  0.057655428  0.0561142818 -0.0235120459
#> Erbb3    -9.843728e-02  0.0121679417  0.201440315 -0.0553532446  0.0438030341
#> Pcdh15    1.998874e-02  0.0304796649  0.058526792 -0.0349101033  0.0521330978
#> Grm7     -3.338724e-02  0.0355627120  0.020473452 -0.1000911557  0.1716592555
#> F2r       1.549603e-01  0.0655745202 -0.086818368 -0.0692260393  0.1130852388
#> Bdkrb2   -4.415963e-02 -0.0588436381 -0.086076129 -0.0863462946  0.1205577456
#> Adgrv1   -1.323651e-02  0.1439844055  0.086699551 -0.2259830019 -0.0303825980
#> Gprc5c    8.620728e-02  0.0153277340  0.110902858  0.1075562888  0.0224857705
#> Tbxa2r   -8.235208e-02  0.0098698867  0.038334444  0.0345995030 -0.0854565427
#> Ackr1    -1.831774e-02 -0.0446091558 -0.049202852 -0.0186152904 -0.0066678322
#> Lpar2     3.916925e-02  0.0520418454  0.086949587 -0.0100194352  0.0013993009
#> Myh11    -1.734374e-02  0.0464736842  0.128354362 -0.0823989557  0.0091982929
#> Musk      1.420258e-01  0.1200756088 -0.088802771 -0.0528757769  0.0411670460
#> Cnr1      1.239605e-03  0.0222121304  0.033677847  0.0112741666  0.0032176017
#> C3ar1    -1.864165e-03 -0.0398766239  0.035853029 -0.0185812194 -0.0453215077
#> S1pr4     3.929798e-02 -0.0656080479  0.074751001 -0.0045482941 -0.0710797499
#> C5ar1    -6.574640e-02 -0.1134052895 -0.055974484 -0.0661784584  0.1015930800
#> Fpr1     -1.135557e-01  0.0649296347 -0.007038102 -0.0255501626  0.0423049175
#> Sctr      1.075215e-01 -0.0775023029  0.014688768 -0.0222430807  0.0228493694
#> Gpr158    3.210956e-01  0.1827852345  0.171148003 -0.0780930999  0.2047212526
#> Cxcr4    -2.404657e-02 -0.0181956487  0.031321822  0.0409752295 -0.0410268751
#> Hrh2     -1.481572e-01 -0.0915637868  0.004560917 -0.1947067988 -0.0511252540
#> Slc17a6   1.944781e-02 -0.0245591105 -0.064260286 -0.0088208413 -0.0154390916
#> Ppp1r3g   9.623146e-03  0.0108886993 -0.054879007 -0.0573771077  0.0462825739
#> Pln      -7.934541e-02  0.0241018518 -0.053936350 -0.0058742348  0.0062657235
#> Grin2b    8.801095e-03 -0.3010850306  0.078458310 -0.0510765245  0.0073081916
#> Taar7e   -7.515084e-02  0.0884732178 -0.050378275 -0.0004016495 -0.0794989187
#> Ptger2   -1.640076e-01 -0.0832545165 -0.128242094 -0.1058812083 -0.1898248819
#> Mc4r     -1.354755e-02  0.1309691658  0.074115489 -0.0553346191  0.0977042140
#> Ghsr     -1.043267e-01  0.0778342550 -0.039263466 -0.1128103024  0.0377625361
#> Nmbr      1.072201e-02  0.0774311468 -0.098071576 -0.1144985782  0.0181678188
#>                Dim.71       Dim.72        Dim.73       Dim.74        Dim.75
#> Mlc1     -0.060559691 -0.050950656  0.1022928436 -0.018755257 -0.1273852264
#> Gprc5b   -0.063104300  0.286250740 -0.0251856093 -0.038993956  0.0550875457
#> Gfap      0.065110279 -0.064439665 -0.0196306516  0.024552527  0.0119924509
#> Ednrb    -0.058516847  0.062645785 -0.0124203832 -0.038077283  0.0711736577
#> Sox9      0.082880214  0.035369083 -0.0739366722 -0.174569439 -0.0932799709
#> Aqp4     -0.032531480 -0.007643029 -0.0158767950 -0.113869475  0.0285774774
#> Gjc3      0.091675499 -0.039255337 -0.0040948021 -0.043561623 -0.0178024173
#> Sox8      0.116895229  0.066927753 -0.0972443985 -0.144672002  0.0168731617
#> Ntsr2    -0.015591112 -0.031524694 -0.0188671179  0.129121017 -0.0847018061
#> Smo      -0.224692032 -0.139799582 -0.1127574648 -0.013620345  0.0438908379
#> C1qb     -0.023277221 -0.083978585  0.0705403411 -0.162778227 -0.0148112351
#> Olig1    -0.053148196 -0.019962569 -0.0173464567 -0.072584330  0.0160094417
#> C1qa      0.039426648 -0.043254062  0.0631424835 -0.139113119  0.0205276659
#> Pth1r    -0.001187810  0.040533385 -0.0966006225  0.062951631 -0.1350839075
#> Gabbr2    0.046118872  0.012660744  0.0108177333 -0.044401072  0.0521251448
#> Timp4    -0.053006936 -0.110923467  0.1081139190  0.134769024 -0.0782112181
#> Abcc9    -0.007908647  0.014986630  0.0726891459 -0.066747179  0.1131103049
#> Csf1r     0.036190447 -0.008103598  0.0031644822  0.175836367  0.0805081945
#> Ntrk2     0.098648011  0.021707565  0.1659145137  0.147629244  0.0951983529
#> Adgrg1    0.024699669 -0.049958349  0.0173139360  0.002571492 -0.1207213763
#> Ntrk3    -0.057384905 -0.083562959 -0.0061604841 -0.179030823 -0.2691322738
#> Erbb4     0.010490645  0.047744514  0.1047638152 -0.028263450  0.0888599345
#> Selplg    0.042660938 -0.028439026 -0.0688687418  0.038770248  0.0401933829
#> Cspg5    -0.004519161 -0.055718106 -0.0271939542 -0.145355323  0.0468352442
#> Dlk1     -0.110660337  0.125386364  0.0777297668  0.069799658  0.0040221451
#> Gpr37l1  -0.078073292  0.110938679 -0.0595206938  0.040679380 -0.1031500316
#> Fgfr3    -0.088658454 -0.052835057  0.2319331029 -0.082535380  0.0624165765
#> Slc25a18 -0.065393512  0.038525963 -0.1580529219 -0.030167095  0.0821272433
#> Igf1r    -0.028591882  0.009023995  0.0770125327  0.056612838  0.0422655194
#> S1pr1     0.131751483 -0.178023590 -0.1113031726 -0.068278231  0.0293735256
#> Grm5      0.098687651  0.026115014  0.1762127827  0.039227284  0.0011007656
#> Axl       0.065805353  0.136747191 -0.0286514220  0.059956125  0.0617320661
#> Efemp1   -0.076220229 -0.129121931 -0.0562871224 -0.032787618  0.0289195308
#> Adgrb3    0.064041974  0.031469693 -0.0031008663 -0.157229323 -0.0410974684
#> Fn1       0.036286143  0.024180024 -0.0368936210 -0.078434365 -0.0193022541
#> Mertk     0.092169020  0.071722932 -0.0440574324 -0.010117281  0.0654870000
#> Adgrl2   -0.131856018 -0.028217458 -0.1340055799 -0.083751561  0.0149735164
#> Fzd2      0.115837403  0.094488379  0.0940590424  0.143806481  0.0211136055
#> Aldh1l1  -0.038335766  0.155998884  0.0142125899  0.031282719  0.0308590798
#> Adgrg6    0.055784075  0.070004096  0.0956388265 -0.059866370  0.0264481726
#> Egfr     -0.076453803 -0.064555290 -0.1362988360  0.046202873  0.1516301307
#> Kit       0.076757025 -0.048191096  0.0097628019 -0.015261147 -0.0029335677
#> Ptgdr    -0.029265026  0.002897508 -0.0690502261 -0.103131874  0.1510723175
#> Gad1     -0.047986395 -0.069248504 -0.0703758795  0.009887484 -0.0341162883
#> Tyro3    -0.030631130 -0.122470370  0.1276345734  0.079224103 -0.0248482228
#> Atp13a5   0.099169748 -0.077913932  0.0090822790  0.079108650  0.0275004530
#> Ddr2     -0.018975384 -0.058400662  0.0375447418  0.029753810 -0.0556353252
#> Rspo3     0.049313998  0.159672913  0.1039126727 -0.090252886 -0.2950482581
#> Arhgap29 -0.020959942 -0.107418816  0.0481068763  0.003069581  0.0944723651
#> Fzd7      0.101548628  0.111416672  0.2088554802  0.277222595  0.1188329761
#> Slc47a1   0.051708942  0.013968140  0.0593560566  0.084578114 -0.0629012098
#> Ptger3    0.051468349 -0.039737984 -0.0573526099 -0.049698682 -0.0162281929
#> Bdkrb1    0.127761941 -0.138731126  0.1608980963 -0.075051234  0.0590207919
#> Traf4    -0.063344704 -0.012534809  0.0203937363  0.144560887  0.0463399743
#> Cx3cr1    0.143654151  0.031789858 -0.0047925510  0.020867781  0.0621503244
#> Anxa11    0.009388242 -0.033943951  0.1442159699  0.105662335  0.0049519296
#> Adgrb1    0.150684850 -0.162891246 -0.2254326478  0.105044561 -0.0944318070
#> Lpar1    -0.058870535 -0.024864632 -0.1245706115  0.004371882 -0.1295023517
#> Gpr17     0.027053603  0.059960360  0.0420375037 -0.001731964  0.0365777244
#> Cxcl12    0.101076179  0.125139444 -0.0374556342 -0.257389544 -0.0221984599
#> Epha4    -0.294763563 -0.075414276 -0.0277372962  0.026642616  0.0518827275
#> Gpr182    0.133006977 -0.001128710 -0.0548371742 -0.011982830 -0.0443853979
#> P2ry14    0.026657020  0.076195817 -0.0076906024  0.117600171  0.0460448912
#> Hcar1    -0.059214971  0.039174103 -0.0936225281 -0.040445328  0.1625684908
#> Ephb1    -0.101019819 -0.046744247  0.1529176941  0.021629283 -0.1404678211
#> Grm3      0.109301186 -0.029724067 -0.1228539379  0.055711961  0.1192337728
#> P2ry1    -0.180612427 -0.026837031  0.0109558247  0.083601305  0.0408412516
#> Ptk7     -0.010507897 -0.064895990  0.1458587935  0.051389172  0.1265438662
#> Slco1a4   0.010247809 -0.082895546  0.0001276429 -0.027588189 -0.0934805234
#> Insrr    -0.082158744  0.037805907  0.0795378949 -0.008487538 -0.0445181066
#> Cmklr1   -0.004152000 -0.023137470  0.1257604252  0.003100938 -0.0263894946
#> Fzd6     -0.081008714 -0.025902064  0.0844757620  0.010606930  0.0006235811
#> S1pr5    -0.022733316  0.047537196 -0.0512570357  0.011060552 -0.0124225958
#> Pdgfrb    0.009121902  0.008915702 -0.1023114767 -0.176491732 -0.1017082329
#> Flt1      0.031452419 -0.013018861 -0.0501526701  0.009772905 -0.0350141819
#> Adgrl4   -0.005513909  0.087751651 -0.0044220610  0.009775016  0.0089576878
#> Lpar6    -0.009826361 -0.078178309  0.0020631523 -0.100706026 -0.0036210347
#> Epha6    -0.121894975  0.055095684  0.2062313111 -0.166419465  0.1678945872
#> Emcn      0.043449920 -0.028290495 -0.0304780762  0.005189266  0.1157880487
#> Cldn5     0.035189418  0.078680386 -0.0467720459 -0.017826302  0.0386936431
#> P2ry12   -0.178236825  0.093585603  0.0011242759 -0.081253246 -0.1264142502
#> Adgrf5   -0.077603642 -0.026613754 -0.0067177286  0.062230559  0.0813823346
#> P2yr13   -0.079648099  0.062733282 -0.1485847766  0.200841669 -0.0352454412
#> Adgre1    0.023379592  0.011143278 -0.0376802157  0.002915943  0.0124277978
#> Cx3cl1   -0.037397708  0.109724067 -0.0842579078  0.135686249  0.1131269610
#> Plxnb3    0.124569927 -0.183848448 -0.0120186075 -0.077876821  0.0107417823
#> Flt4      0.094907782 -0.032516940 -0.1425573097  0.070694990  0.1707816625
#> Slc17a7   0.104236653 -0.213271141  0.0138193008  0.074494125 -0.0968776258
#> Cd300c2   0.049152009 -0.018961612  0.0194293868  0.003806559  0.0687467162
#> Tek      -0.007670036  0.107529236  0.2391819060 -0.050292116  0.0018261780
#> Kdr      -0.019381754 -0.002021575  0.0451753736 -0.054807464  0.0224094181
#> Kcnj8    -0.005558235  0.012980134 -0.0277121970 -0.047229748 -0.1231623118
#> S1pr3    -0.127394091  0.021648696  0.0175628003 -0.017508824 -0.0248130574
#> Tie1      0.008215865 -0.146948617 -0.0485479008  0.039243866 -0.1254431631
#> Pdgfra   -0.090384602 -0.056379918  0.0331875230  0.073043289 -0.1358707139
#> Baiap2    0.103627350  0.164105029  0.0565464234  0.037955166 -0.0261337736
#> Calcrl   -0.030020670 -0.109678204 -0.1254510999  0.163198581 -0.0862017149
#> Adrb2     0.002161610  0.088005914 -0.0241958440 -0.025731530 -0.0285909318
#> Ccr2     -0.208463359  0.044159734 -0.1422987412  0.140113228 -0.1372275759
#> Alk      -0.084746657 -0.036533273  0.0464469251 -0.012244701 -0.0149087274
#> Tacr3     0.077760336  0.128150600  0.0022168409  0.036205854 -0.0953883249
#> Erbb3    -0.144530162  0.030135373  0.0767444070  0.037887542  0.0086161100
#> Pcdh15    0.014829554  0.007248258 -0.0211172492  0.112911203  0.0301431138
#> Grm7     -0.047209521  0.105826237 -0.1215784923 -0.089147272  0.1116265036
#> F2r      -0.030329587  0.028170487  0.0749223907 -0.112193761 -0.0218313770
#> Bdkrb2    0.137587609  0.033391732  0.0002635216 -0.029210482  0.0628804221
#> Adgrv1   -0.016049451 -0.027250083 -0.0180509832 -0.044595126  0.1089364143
#> Gprc5c   -0.114962935  0.215002898 -0.0340260345  0.044331893 -0.1009861606
#> Tbxa2r   -0.089298824 -0.111843703  0.0940002112  0.061147276  0.0245176681
#> Ackr1    -0.128625115 -0.022980789  0.0332587304  0.040003594  0.0439962906
#> Lpar2    -0.024285271  0.024547820  0.0321658867 -0.008548279 -0.0394970902
#> Myh11     0.050344685  0.010990289 -0.1060057159  0.047070393  0.0278885561
#> Musk     -0.125214290 -0.169802429  0.0001039446 -0.035932161  0.0812629584
#> Cnr1      0.038376210  0.116879598 -0.0127700809 -0.001983683 -0.0331605346
#> C3ar1    -0.125735276  0.069509768 -0.0910894863  0.174240351 -0.1569059637
#> S1pr4    -0.054025801  0.046655947  0.0790624390 -0.101284971 -0.1315372025
#> C5ar1     0.079675134  0.013193643 -0.0797084519  0.059000007  0.0752920821
#> Fpr1     -0.104878749 -0.017347497 -0.0208630069 -0.104059744 -0.0468103471
#> Sctr     -0.050468735  0.069985910 -0.0151862557 -0.022359392 -0.0080035183
#> Gpr158    0.131369538 -0.113953865 -0.1356260208 -0.041406388 -0.0023394918
#> Cxcr4    -0.008670854 -0.009210456 -0.0005997615 -0.007249846 -0.0286132290
#> Hrh2     -0.130491936 -0.119811469  0.1015890625 -0.039165314  0.0176380121
#> Slc17a6   0.060163594 -0.041283659 -0.0479424058  0.047416627  0.0093347458
#> Ppp1r3g  -0.066629853 -0.013792342 -0.0585162403  0.126508444 -0.0662379240
#> Pln       0.079018611 -0.028710834  0.0087757763 -0.005087685  0.1033973260
#> Grin2b   -0.111822627  0.243692045 -0.1578893097 -0.082824719  0.1513802580
#> Taar7e   -0.047234773 -0.035073135  0.0476735877 -0.050495762 -0.0040686524
#> Ptger2    0.106915541  0.010806603 -0.0462962406  0.062192881 -0.1690984676
#> Mc4r     -0.216306566 -0.155642589 -0.0712733495 -0.066852618  0.2659486098
#> Ghsr     -0.003243523  0.092192635 -0.0514766228 -0.050259131  0.0318545930
#> Nmbr     -0.030472123  0.138068709 -0.0914862322  0.021187606  0.0183807215
#>                 Dim.76        Dim.77        Dim.78        Dim.79        Dim.80
#> Mlc1     -0.0363355712 -0.0145850457  4.619688e-02 -0.0827422236 -0.2286119280
#> Gprc5b    0.0378449691  0.1408382865 -2.108614e-01  0.0589767365 -0.0211923850
#> Gfap     -0.0358361030 -0.0318860948 -3.667653e-02  0.0377614621  0.0083006782
#> Ednrb     0.0544582259 -0.0790516103 -1.767260e-01  0.0612266925 -0.0966505028
#> Sox9     -0.0423490415  0.1829919235  1.022337e-01 -0.0440008623  0.0249128488
#> Aqp4     -0.0490670917  0.0312792174  1.604871e-01 -0.0203047670 -0.0206999055
#> Gjc3      0.0040269543 -0.0118508993  2.115296e-03 -0.1311189707  0.1275781304
#> Sox8      0.0154296858  0.0921118891  1.099499e-01  0.2129670877  0.1750382804
#> Ntsr2     0.0555101521  0.0334074512 -8.656427e-02  0.0011841208  0.0452857527
#> Smo       0.0047894203  0.1232687312 -9.303399e-04 -0.0271568814  0.0253260703
#> C1qb      0.0478372170  0.0304290715  6.717821e-02 -0.0494929893  0.0201865056
#> Olig1     0.0494195615 -0.0382916207  2.342742e-02 -0.1271106990 -0.1839703352
#> C1qa      0.0611427730 -0.0092837490  6.203749e-02  0.0273246218 -0.0082114823
#> Pth1r    -0.1096084532 -0.0674148034  4.511431e-02 -0.0849483486  0.0447609778
#> Gabbr2   -0.1130569980  0.0846608280  1.968073e-01 -0.0555984294 -0.0731710691
#> Timp4     0.1263856775 -0.0030835233 -1.645243e-02  0.1049776872  0.0892833384
#> Abcc9     0.1826401727  0.1421652865 -7.319609e-02 -0.0560503173 -0.0030302058
#> Csf1r     0.0046355290  0.0641369775 -9.832798e-02 -0.0448371208 -0.0245870961
#> Ntrk2     0.2037201363  0.0217331969  2.091932e-02  0.0244895404  0.3759422328
#> Adgrg1   -0.0578984680 -0.0573947087  8.177562e-02  0.0470807182  0.1292144826
#> Ntrk3    -0.0710488939 -0.2061473876 -1.524915e-01 -0.0565253864 -0.0302339522
#> Erbb4    -0.0953303470  0.1293148032 -1.501850e-01 -0.1623917938  0.0463883134
#> Selplg   -0.2322851583  0.0297233284 -8.647665e-02  0.0434054587  0.0473792620
#> Cspg5    -0.1518318569  0.0900088395 -3.953102e-02  0.1227085636  0.0071160477
#> Dlk1      0.0625768921 -0.0003054694 -4.654048e-02 -0.0176091706 -0.0935692458
#> Gpr37l1   0.0264995083  0.0239750508 -1.288843e-01 -0.0690497219 -0.1208690615
#> Fgfr3     0.0465398498  0.1401291817  2.132495e-01  0.0372214881 -0.0861244140
#> Slc25a18 -0.0435888626 -0.1779055393 -4.778637e-02 -0.0052799722 -0.2224713545
#> Igf1r     0.0747048584  0.1654967803  1.210928e-01 -0.0715755555 -0.0604122390
#> S1pr1     0.0442306278 -0.1133540339 -1.197171e-01 -0.0932948193  0.0303706699
#> Grm5     -0.1338209139  0.2319024076 -3.959755e-02 -0.0485246500 -0.0323851915
#> Axl       0.0826296026 -0.1164918690 -8.938248e-03 -0.0857293880  0.0123623205
#> Efemp1    0.0316806632  0.0619865727  8.706941e-02  0.0998284791  0.0273842532
#> Adgrb3    0.0682007357  0.0325455170 -3.481689e-02 -0.0512028188 -0.0031584051
#> Fn1      -0.0038519258  0.0455066318  1.842734e-02  0.0248713324 -0.0198623485
#> Mertk    -0.0198082836 -0.1637886302 -1.210735e-02  0.0711536213 -0.0633425862
#> Adgrl2    0.0720700714  0.1563693141 -5.897087e-02 -0.0815778607 -0.0447727688
#> Fzd2     -0.0966759738 -0.0939515765 -1.197041e-02 -0.0813943337  0.1076128857
#> Aldh1l1  -0.0013086915 -0.1275540425  1.506279e-01 -0.0072982955 -0.0930111260
#> Adgrg6    0.0530038219 -0.0658479530 -1.388035e-01  0.1545743274  0.0585043790
#> Egfr     -0.2603799282  0.0468905204  8.295931e-02 -0.0641833853  0.0688460234
#> Kit       0.0450426937  0.0182436506  3.543153e-02 -0.0458470023 -0.0606077450
#> Ptgdr     0.0929971881  0.0886538028  3.662809e-02  0.1243810600 -0.1552982897
#> Gad1      0.0844120085 -0.1252449059  1.205522e-02  0.1359940178  0.0097745236
#> Tyro3    -0.1444913632 -0.0586614776  6.465287e-02  0.3048110683 -0.0540606896
#> Atp13a5  -0.0552501205 -0.0218025098 -2.288236e-02 -0.0035680573 -0.0627137145
#> Ddr2     -0.0508719870 -0.1007551405 -2.958171e-02 -0.1442772472  0.0556476249
#> Rspo3     0.0338330458 -0.0542197124 -6.765473e-02 -0.1873662386  0.0046042496
#> Arhgap29  0.0807445491 -0.0001153793  8.071399e-02  0.1030840002 -0.0644647035
#> Fzd7     -0.0436997161 -0.0548530561 -4.980433e-02 -0.0374893985 -0.0748534653
#> Slc47a1   0.0087582645 -0.0517938717 -5.079785e-03  0.0241306334 -0.0435709406
#> Ptger3    0.0368987806  0.0688256562 -5.803567e-02 -0.0936473395  0.0746865433
#> Bdkrb1    0.0329121080 -0.1000481608  5.177176e-02  0.0166607719 -0.0518769411
#> Traf4     0.0398456972  0.0330790356 -1.965694e-02  0.1185728816  0.0764863235
#> Cx3cr1   -0.0410060213 -0.1130256354  3.264678e-02 -0.0284754493  0.0344127890
#> Anxa11   -0.0414437162  0.0792399040 -4.027865e-02  0.0206615906 -0.1181902216
#> Adgrb1    0.2729268719 -0.0388388740  6.540292e-02  0.0576916634 -0.2010228841
#> Lpar1    -0.0415085486  0.0348881853  1.091373e-01  0.0553319100  0.1421372606
#> Gpr17     0.0032016089 -0.0198702249 -1.672234e-02 -0.2128814855 -0.0753817921
#> Cxcl12    0.0095354248  0.0284045785 -1.582160e-01  0.1804325939 -0.0054606697
#> Epha4     0.1978961841 -0.1485884850 -1.287429e-01 -0.2141727029  0.2116429636
#> Gpr182   -0.0162499074 -0.0161425738 -1.476342e-01 -0.1221477943 -0.0473299512
#> P2ry14   -0.0772437717 -0.0623492782 -1.124091e-02  0.0470685012  0.0023902668
#> Hcar1     0.0021060685 -0.0089962935  5.536445e-02 -0.0355671638 -0.1393775600
#> Ephb1    -0.1992170360  0.0780243628  7.084537e-04 -0.0410192452  0.0079085436
#> Grm3     -0.1316824466 -0.1233140069  1.505651e-01 -0.1331179247 -0.1339327576
#> P2ry1    -0.1007682917  0.0222584599  7.551530e-02 -0.0813933903 -0.0470920059
#> Ptk7     -0.0525628308  0.0512145288 -2.747049e-02 -0.0689726023  0.0315609010
#> Slco1a4  -0.0933132472  0.0471517140 -1.358988e-01 -0.0179708094 -0.1019919126
#> Insrr     0.0821974479 -0.0141710807  7.455271e-03  0.0085840246  0.0680143345
#> Cmklr1   -0.0432580214  0.0222173019  1.213038e-02  0.1202270029 -0.0410927874
#> Fzd6      0.0250430289 -0.0273719775  8.057744e-02 -0.0080968344  0.0002633071
#> S1pr5     0.1699856207  0.0151161592 -6.826067e-02  0.1135536878  0.0283736078
#> Pdgfrb   -0.0702083431 -0.0335570848  1.184078e-01 -0.0371727515  0.0370642654
#> Flt1      0.0410303616 -0.1623786561 -1.061110e-01  0.0929263722 -0.0335727245
#> Adgrl4   -0.0744578770  0.0643895826  2.897772e-02 -0.0423981794  0.0217017849
#> Lpar6     0.0578828676 -0.0697921425  3.960271e-02 -0.0172022802  0.0439216471
#> Epha6    -0.1740711124 -0.1260203832 -3.443853e-02  0.0245462517  0.0084451230
#> Emcn      0.1117072284  0.0748040016 -1.105911e-01  0.0015341114  0.0447229918
#> Cldn5     0.0158847440  0.0769490294  2.268918e-02 -0.0397490744  0.0291013802
#> P2ry12    0.1389404589 -0.0256037950  8.026131e-02 -0.0104299034 -0.0502138053
#> Adgrf5   -0.0142220032  0.0021463003  1.644623e-01 -0.0830476018  0.0576580532
#> P2yr13   -0.0096114960  0.1231481736 -1.506480e-01  0.0791215869 -0.0527619195
#> Adgre1    0.0339938167 -0.0827248192  1.140248e-02 -0.0704072565 -0.0600671676
#> Cx3cl1    0.1739816415 -0.0550031446  1.601526e-01 -0.0393460397 -0.0062745083
#> Plxnb3   -0.0539509892 -0.0451823625 -4.287604e-02  0.0847098335  0.0802834011
#> Flt4     -0.0012230056 -0.1052873187  6.401684e-02  0.0739900899 -0.0256397021
#> Slc17a7   0.0190030184  0.0388135682 -1.137889e-01  0.0583866880 -0.1111693785
#> Cd300c2  -0.0120538397 -0.0223582199 -5.733176e-02 -0.0143223030  0.0248971829
#> Tek      -0.0095093428 -0.0562624922 -1.506817e-02  0.0961611427  0.0091508760
#> Kdr      -0.1193318122 -0.0169945768 -6.778868e-02 -0.0663464302 -0.1384546129
#> Kcnj8    -0.0330823272  0.0377115301  4.100845e-02 -0.0309045506  0.0059744366
#> S1pr3     0.1257233369  0.0415924694 -3.368253e-02  0.0691431969  0.0985217164
#> Tie1     -0.0001737544 -0.0578651194  7.836068e-02 -0.0024042144  0.1279032672
#> Pdgfra   -0.0599125953  0.0539507418  2.392577e-02  0.0391562760  0.1095946997
#> Baiap2    0.0559107795 -0.0383318910  1.374346e-01  0.0043857533 -0.0629922296
#> Calcrl   -0.0064588693 -0.0931802310  1.298936e-01  0.0490509106 -0.0429053004
#> Adrb2     0.0108691063  0.0490653556  4.380074e-03 -0.0305979681  0.0101463145
#> Ccr2     -0.0578373929  0.1054229795 -4.599388e-02  0.0205562403 -0.0246245682
#> Alk       0.0116086383  0.0948584740 -7.040831e-02  0.1534694864 -0.0183842735
#> Tacr3     0.0711322798  0.0499749534  1.289962e-01  0.0737663570 -0.0121843993
#> Erbb3     0.0941613621 -0.0054133025 -1.042618e-02 -0.0885299818 -0.1220656048
#> Pcdh15   -0.0286616954 -0.0341530564  2.503556e-05  0.1763402366  0.0342324909
#> Grm7     -0.0547467637 -0.1627361311 -5.901421e-02  0.1642366139  0.0436076926
#> F2r       0.0004674493 -0.1074030976  7.598153e-02  0.1260301835  0.0188770088
#> Bdkrb2    0.0217584627 -0.0137170807 -6.977910e-02  0.0282272397  0.0050616562
#> Adgrv1    0.0494049139 -0.0389058136 -1.316207e-01  0.0057301486  0.1323432794
#> Gprc5c   -0.0443731621 -0.0687569505 -7.860086e-02  0.0994528214  0.0433155886
#> Tbxa2r   -0.0365319183 -0.0197471560 -2.088756e-02  0.1132764609 -0.0726937623
#> Ackr1     0.0800119932  0.0792421576  2.676663e-02 -0.0402310903  0.0087411884
#> Lpar2     0.1056304559 -0.0029641070  1.780869e-01 -0.0332162486  0.0793253784
#> Myh11     0.0144281911 -0.0464288788 -1.411834e-03 -0.0459868790 -0.0051649687
#> Musk      0.0656672619 -0.0476787296 -8.177055e-02 -0.0239648061 -0.0786758229
#> Cnr1     -0.0014192105  0.0035849168  9.162548e-02 -0.0276969549 -0.0279960472
#> C3ar1    -0.1311069797  0.0716111422 -6.570013e-02  0.1243819813 -0.0162806350
#> S1pr4     0.0319407828 -0.1083394571 -8.205955e-02  0.0475249731 -0.0523493951
#> C5ar1     0.0835207283  0.1059874838 -5.281588e-02 -0.0417692154 -0.0841209585
#> Fpr1      0.1169890643  0.0335406649  1.362155e-01 -0.0828701932  0.0543940443
#> Sctr      0.0197145876  0.0658662605  5.272389e-02  0.1860293442 -0.2439555775
#> Gpr158   -0.0886371498  0.3145306831 -9.340059e-02 -0.0316687474  0.0494743274
#> Cxcr4    -0.0703100779 -0.0429129596 -1.127758e-02 -0.0206795470 -0.0176666130
#> Hrh2     -0.0248799200 -0.1901193315  1.679709e-02 -0.0012646053 -0.0182938290
#> Slc17a6   0.0088166909 -0.0707498438 -4.748368e-02 -0.0799726348  0.1049215432
#> Ppp1r3g  -0.1641733705 -0.0507014230  8.750264e-02 -0.0354750424  0.0893140330
#> Pln       0.0002424275  0.0612874494 -2.284823e-03 -0.0627246611 -0.0895280165
#> Grin2b   -0.1601821140 -0.0397917030  1.420783e-01  0.0381312596  0.1261084076
#> Taar7e   -0.1158512547 -0.1101975798 -8.198578e-02 -0.0595354115  0.0256896070
#> Ptger2    0.0186546780  0.0693885108  1.935567e-02  0.0205028835 -0.0709532479
#> Mc4r     -0.0692233244 -0.0130575857 -1.383449e-01 -0.0001251354  0.0326516777
#> Ghsr     -0.1002845603  0.0157519532 -7.428544e-03  0.0214926474  0.1154889747
#> Nmbr      0.0116987931 -0.0560298097 -1.098731e-02 -0.0983196070  0.0451396033
#>                Dim.81        Dim.82        Dim.83        Dim.84        Dim.85
#> Mlc1     -0.093735387  0.1200973176 -0.0160785957  0.1336642551  0.0793526409
#> Gprc5b   -0.004330739  0.0230413421  0.0047498014  0.0884552400  0.0105176609
#> Gfap      0.051426761 -0.0628112513 -0.0209238625  0.0023613787  0.0108277007
#> Ednrb    -0.150908441 -0.0282064825  0.1678329384 -0.0291582135  0.2441313287
#> Sox9      0.070901568 -0.0612837992 -0.0745932300  0.0142183784 -0.0576132217
#> Aqp4     -0.078194229  0.2058795931 -0.0184833864 -0.0194567997 -0.0230407479
#> Gjc3      0.092813453 -0.0538281269  0.0600185714  0.0885473595 -0.1089634311
#> Sox8     -0.122443709  0.0952410306  0.1252869154  0.0398065303 -0.1503193599
#> Ntsr2    -0.014035892 -0.1323497662 -0.0533465028  0.0758342228 -0.0500524979
#> Smo      -0.165099942 -0.0210943075 -0.1108363230  0.2040286379  0.0990239405
#> C1qb     -0.059329219 -0.1098273049  0.0024608868 -0.1270682887 -0.0514775681
#> Olig1     0.074402136 -0.0806522540 -0.1521452273  0.0221041139 -0.0168247154
#> C1qa      0.008506292 -0.0303846703  0.0025777237  0.0729904963 -0.0705206723
#> Pth1r    -0.097529836 -0.0777161834  0.0593022443 -0.1261974022  0.0080101626
#> Gabbr2    0.050500647 -0.1376070838  0.1828769780  0.0042395710  0.0860778897
#> Timp4    -0.053985809 -0.0103088207 -0.0349899576 -0.0009470189  0.0785925946
#> Abcc9    -0.084000979  0.0481453110  0.0300460317 -0.0303041154 -0.0358995446
#> Csf1r    -0.023856999  0.0072382401 -0.0193290958 -0.0060316055  0.0270143678
#> Ntrk2     0.057003878  0.0271395619 -0.0373520180 -0.0591720512  0.0719077231
#> Adgrg1   -0.032633384  0.0523410286 -0.1092554370 -0.2119288979 -0.1244712114
#> Ntrk3     0.184167727 -0.0052183942 -0.0457542903  0.1335193784  0.1305230486
#> Erbb4     0.022719586  0.0403344003  0.0106936040  0.0114230827 -0.0931475983
#> Selplg    0.119420394  0.0019057928  0.0201809859 -0.0117402780 -0.0017012819
#> Cspg5    -0.055727227 -0.0341658044  0.1250707131  0.1442527391 -0.0420218035
#> Dlk1     -0.018414694 -0.0275189532 -0.0010024202 -0.0649090699 -0.1129470891
#> Gpr37l1  -0.068786541 -0.2576964841  0.0489630383  0.0434810435  0.0071331021
#> Fgfr3     0.132117015  0.1804626755  0.0093820869 -0.1255848657 -0.0741670774
#> Slc25a18  0.017735221  0.1511728119  0.0283768842 -0.1208252332  0.0110099331
#> Igf1r     0.122323547 -0.0220986197 -0.0153538013  0.0580046362 -0.1251907183
#> S1pr1     0.098165575  0.0717365792  0.0788429479  0.0464750260 -0.0898707564
#> Grm5      0.158893312 -0.0245137518  0.0598589637 -0.0420515081  0.2497392118
#> Axl      -0.098346838  0.0372442597 -0.0503337550 -0.0532898638  0.1678125967
#> Efemp1    0.068470705 -0.0804955997  0.0308911141  0.1443210531 -0.0128082459
#> Adgrb3   -0.113504658  0.0293691951 -0.0464523296  0.0478208033  0.0528604849
#> Fn1      -0.036487071  0.0489999345 -0.1096257886 -0.0575619377  0.0453148701
#> Mertk     0.029489096  0.0029953317  0.0426388017 -0.0288841273 -0.1268492175
#> Adgrl2    0.002953736 -0.1020826135  0.1090301988 -0.2094479581 -0.0557262594
#> Fzd2     -0.138129078 -0.0217151728  0.0256563905  0.0817216866 -0.0202232053
#> Aldh1l1   0.053356541 -0.0384042048 -0.0170205676  0.0409807696  0.0707628310
#> Adgrg6    0.004449662 -0.0505498312 -0.0829132231  0.0657147804 -0.0201166244
#> Egfr     -0.133535664 -0.1243481550 -0.4432832708 -0.0106905826  0.1482925886
#> Kit       0.026742829  0.0314906484 -0.0115530882 -0.0278371370 -0.0041457159
#> Ptgdr     0.005354746  0.1040894668  0.0141634041 -0.0576823501 -0.0605783251
#> Gad1     -0.056547558 -0.0361165158 -0.0132463950 -0.0237646789  0.0006399957
#> Tyro3    -0.076695541  0.1344567982  0.0465629212 -0.1483871063 -0.1150626940
#> Atp13a5   0.063483461 -0.0221045012  0.0630452534 -0.0553326727 -0.0812343112
#> Ddr2     -0.027766826 -0.0580709862  0.1198700458  0.0091584849  0.0144595563
#> Rspo3     0.113088557  0.2164508702 -0.0493329731 -0.0042624743  0.0401556101
#> Arhgap29  0.034794911  0.1340649463  0.0975341849 -0.0484821398 -0.0176624386
#> Fzd7      0.030534888 -0.0737895048  0.0298190523  0.0445103314 -0.0266417723
#> Slc47a1   0.002414622 -0.0116127627  0.1881597736 -0.0575984497  0.0338414335
#> Ptger3    0.020971315 -0.0858008902  0.0471187179 -0.0972593225  0.0115405388
#> Bdkrb1   -0.005632865  0.0015174666 -0.1083891291  0.3034279659 -0.0571970683
#> Traf4     0.127200387  0.0290749941 -0.2078394820  0.1385487525 -0.0061526142
#> Cx3cr1    0.073344614  0.0202269269 -0.0344100298  0.0327389794  0.1356894848
#> Anxa11   -0.205003102  0.0218770431 -0.1147588917 -0.0467618665 -0.0096104694
#> Adgrb1   -0.010245871 -0.0289001310 -0.0406959418  0.0850357347 -0.1399789458
#> Lpar1    -0.100519996 -0.0296181051 -0.0303608873  0.0284140963  0.1079446603
#> Gpr17    -0.037413183 -0.0409449419  0.1066698878 -0.0904712564 -0.0042850736
#> Cxcl12    0.166303218 -0.0741088720 -0.0987652140 -0.1045173035  0.0379263063
#> Epha4     0.236215472  0.1187559210 -0.1014044458 -0.2576374317 -0.0288992920
#> Gpr182   -0.007325424  0.1239147034  0.0567236821 -0.0303465614 -0.0172635204
#> P2ry14    0.026060228  0.0623355729 -0.1191555344  0.1284210156 -0.0615401150
#> Hcar1    -0.017866841 -0.0878042377 -0.0253030057  0.0218291965 -0.1156933762
#> Ephb1    -0.006609463  0.0556474977  0.0607459593 -0.1802441884  0.0067445497
#> Grm3      0.087976984 -0.0172607813 -0.0414884321 -0.0473811798  0.1605742802
#> P2ry1    -0.046186003  0.1353774255  0.0579385318  0.1446826680 -0.0586571090
#> Ptk7     -0.096323825  0.1641962315  0.0216347633  0.0616541843 -0.0307671660
#> Slco1a4  -0.092257226  0.0641209606  0.0799656090  0.1018008345 -0.0074273235
#> Insrr    -0.059080030 -0.0670002809 -0.0310309035  0.1380043199  0.0266727706
#> Cmklr1   -0.061271398 -0.0383254611 -0.0126749000 -0.1366653701 -0.0442663116
#> Fzd6      0.053287406 -0.1081961814  0.0797959776 -0.0092843009  0.0709059583
#> S1pr5    -0.101201473  0.0273667827  0.0480230199 -0.0692913512  0.1770706385
#> Pdgfrb   -0.051505924  0.0364359113 -0.1830693271 -0.0753629471  0.0507032542
#> Flt1     -0.038053300  0.0767461723  0.0208032046 -0.0537280068 -0.0615250878
#> Adgrl4    0.026253555 -0.0268851874 -0.0377383111 -0.0297586542  0.0100685614
#> Lpar6     0.071099049 -0.0220534155  0.0066036776  0.0916356476  0.0322774410
#> Epha6    -0.023285186 -0.1823371659 -0.0069725568 -0.0382722419  0.0177770319
#> Emcn     -0.185055908  0.0024771658  0.0003246873 -0.0001023792  0.1275890844
#> Cldn5    -0.005991687  0.0458753655 -0.1251857613 -0.0118347265  0.0297507920
#> P2ry12   -0.197614091  0.0387684568  0.0214227613 -0.0147775014  0.0438934561
#> Adgrf5    0.010745935 -0.1632673109  0.1081391279 -0.0029739122  0.0350290076
#> P2yr13    0.179447022  0.0572060389 -0.0278561314  0.1064854478 -0.1103962367
#> Adgre1   -0.052122112  0.0176002566  0.1360406511  0.1011271489  0.0047794617
#> Cx3cl1    0.098913594  0.0786969858  0.1179818711  0.1422956979 -0.0695686299
#> Plxnb3    0.002883744  0.0072856985  0.0137006839  0.0883121522  0.1875815346
#> Flt4      0.096013501 -0.0247383588 -0.1021594334 -0.1251698885 -0.0021921914
#> Slc17a7  -0.256499781 -0.0782267820 -0.0653459735 -0.0471411164 -0.0838828422
#> Cd300c2   0.015434046  0.0945279368  0.0423602416  0.0735319305 -0.0023573835
#> Tek       0.065209708 -0.0462791237  0.0200272894  0.1305409348 -0.0477164219
#> Kdr       0.004992421  0.0467759451 -0.0132908062  0.0838992391 -0.0444099964
#> Kcnj8    -0.006457918  0.0137809431  0.0077145057  0.0735818538 -0.0634035547
#> S1pr3     0.080031181  0.0215036975 -0.0091979488  0.1529445656  0.1258799645
#> Tie1     -0.009394909 -0.1332618374  0.2182733559  0.1134867086  0.1495459134
#> Pdgfra   -0.024210376 -0.1301655468 -0.0157326771 -0.1138978194 -0.0861137852
#> Baiap2   -0.086956494 -0.0217690733 -0.2253096697 -0.0436361141 -0.0404289886
#> Calcrl    0.095010135  0.0287122339  0.0330597124 -0.0030495130 -0.0184638459
#> Adrb2    -0.004960049  0.1767430408 -0.0227114221  0.0274593626 -0.0143647826
#> Ccr2      0.068857935  0.1079559698  0.0220579132  0.0950169039 -0.0317731027
#> Alk       0.115865387  0.0844081755  0.0250473222 -0.0431262849  0.0344749285
#> Tacr3    -0.051025366 -0.1259265507  0.0828404405 -0.0514782206 -0.0486880966
#> Erbb3    -0.150982847 -0.0644175904 -0.0784411207  0.0645418493 -0.0734840167
#> Pcdh15   -0.118717951  0.2693692684  0.0205868683 -0.0427408517  0.2768821344
#> Grm7     -0.092151484 -0.1024376606  0.1144558682 -0.1056192634 -0.0453776912
#> F2r       0.105792536  0.0144681129 -0.1002946522  0.0456532091 -0.0794064443
#> Bdkrb2    0.006001383 -0.0459385959  0.0088333126 -0.0305198133 -0.0526452216
#> Adgrv1   -0.026158465 -0.2056272141 -0.1198631418  0.0233466285 -0.2518471017
#> Gprc5c   -0.023790564 -0.0678341827  0.1192417349  0.0314452670 -0.0645376975
#> Tbxa2r    0.140387432 -0.1359503411  0.0385701747  0.0276742671  0.0093499153
#> Ackr1    -0.029065291 -0.0578602700  0.0755327226 -0.0082264946  0.0336118587
#> Lpar2    -0.062835829 -0.0388571222  0.0238483036  0.0313594088  0.0680303424
#> Myh11     0.024970701  0.0200975461  0.1009525960 -0.0326637175 -0.0211099112
#> Musk      0.063985092  0.0535659480 -0.0550955508 -0.0079134786  0.0937532730
#> Cnr1     -0.013906595 -0.0051928058 -0.0156992706  0.0061304241  0.0403338016
#> C3ar1     0.040076607  0.0062155089 -0.1244926028 -0.0492635936 -0.0471373831
#> S1pr4    -0.065958029 -0.0107962960 -0.0762538210  0.0620445279 -0.0655559389
#> C5ar1    -0.063637211 -0.0071225936 -0.0490415793 -0.1249847305  0.0498359527
#> Fpr1     -0.007449543  0.0349705591  0.0454274730 -0.0330372227  0.0021663403
#> Sctr      0.217948125 -0.2021586654 -0.0313647208 -0.0323918549  0.2127553516
#> Gpr158   -0.010826408  0.0262009227  0.0733116753  0.0279112388 -0.1041623031
#> Cxcr4    -0.076691016  0.0345196880  0.0775273150 -0.0060655988 -0.0866485357
#> Hrh2     -0.099014764 -0.0467100393  0.0278380198 -0.0417478197 -0.0970706786
#> Slc17a6  -0.082618502  0.0339428623 -0.0348717086  0.0473219326  0.0196922049
#> Ppp1r3g   0.013087120  0.0001441324  0.0678246439 -0.0276088484 -0.1342479581
#> Pln      -0.060753126 -0.0002540803 -0.0455250134  0.0102654582 -0.0195768585
#> Grin2b   -0.069454630  0.1341492975  0.0771539648  0.1749918653 -0.0473794907
#> Taar7e   -0.032709596  0.0944560187 -0.0695272893 -0.0133027666 -0.0999029114
#> Ptger2    0.044539693  0.0204023883 -0.0229346732  0.0242302762  0.0367794357
#> Mc4r      0.013592632  0.0278544767  0.0774813171  0.0160754232  0.0464084266
#> Ghsr      0.057581076  0.0104375508  0.0562762594 -0.0150781170  0.0521752668
#> Nmbr     -0.027601323 -0.0431472576 -0.0146725241  0.0152135724 -0.1101811620
#>                 Dim.86        Dim.87        Dim.88       Dim.89        Dim.90
#> Mlc1     -0.0446194521 -1.805083e-02  0.1484667185  0.078401733 -2.924862e-02
#> Gprc5b    0.0747662202 -4.475160e-02 -0.2115922857 -0.105664583 -5.921809e-02
#> Gfap      0.0155304162  1.903392e-02 -0.0666472414  0.066194824 -2.246512e-02
#> Ednrb     0.0512531207  3.987415e-03  0.2369214973  0.166821179 -2.950391e-02
#> Sox9     -0.0350224532  1.287844e-01  0.0315784750  0.088571993 -1.438889e-03
#> Aqp4     -0.0409703527 -7.632461e-02 -0.0185938481 -0.174663056  1.345998e-02
#> Gjc3      0.0253485452  7.446386e-02  0.1748230538  0.056229272  9.247124e-02
#> Sox8     -0.0600121991  7.987573e-02  0.0152099579 -0.044230580 -1.182730e-01
#> Ntsr2    -0.0328373691  5.558512e-02  0.0091378822  0.059867405  1.238556e-02
#> Smo       0.0026082270 -8.615144e-05  0.1097382639  0.004404282  9.167016e-02
#> C1qb     -0.0463971696 -7.029504e-02  0.0017497232  0.029113934  5.680070e-02
#> Olig1     0.0475466556 -2.586215e-02 -0.1024841085 -0.158382061 -6.533709e-02
#> C1qa      0.0327250841  7.903381e-02 -0.0883805004 -0.004993833 -1.239920e-04
#> Pth1r    -0.0340636713 -7.034020e-02  0.0232577748  0.073222547 -2.297609e-02
#> Gabbr2    0.2467788563 -2.335529e-01  0.1066481236  0.009390707  1.378517e-01
#> Timp4     0.0344405694 -2.093301e-01 -0.2507068893  0.093717686  4.694750e-02
#> Abcc9    -0.1654077683  1.239701e-02  0.0133393661 -0.106839592  8.088886e-02
#> Csf1r    -0.0911006034  6.607610e-02 -0.0175853355 -0.083767182 -2.424711e-02
#> Ntrk2     0.0909720851  1.162075e-01  0.2498873675 -0.060203665 -5.733222e-02
#> Adgrg1    0.1604057654 -7.367918e-02 -0.0786447060 -0.011826503  1.166184e-01
#> Ntrk3    -0.0702398451 -1.291608e-01  0.0514904569 -0.189859230 -2.138488e-01
#> Erbb4    -0.1204752552 -7.039966e-02 -0.0068576943  0.092890744  2.754632e-02
#> Selplg   -0.0754350766  6.230948e-02  0.1336268565  0.063006232 -6.318817e-02
#> Cspg5    -0.0887596276 -1.065305e-01 -0.0557288014  0.051694191 -2.038485e-02
#> Dlk1     -0.0114570157  1.415152e-01  0.0767420697 -0.054251363  6.092212e-02
#> Gpr37l1   0.0100927556  1.574754e-01 -0.0523048732  0.085128714 -4.366962e-02
#> Fgfr3    -0.1019314966 -5.537155e-02  0.0190798414 -0.033899780 -9.996322e-02
#> Slc25a18  0.0111218317  5.032591e-02 -0.0940290665 -0.121073844  5.010449e-02
#> Igf1r     0.2054869791  1.404098e-01  0.0338512596 -0.087277620 -2.845034e-02
#> S1pr1    -0.0150071577 -1.081918e-01 -0.0680190781 -0.125823251  8.775953e-02
#> Grm5     -0.0681448131  2.929161e-02 -0.0651909556 -0.098733711  1.579165e-01
#> Axl       0.0590108802 -1.080991e-01  0.0771046579  0.007894065 -5.397611e-02
#> Efemp1   -0.1154580606  7.907215e-03 -0.0424233822 -0.051372093  2.600285e-02
#> Adgrb3    0.0321149563  3.287189e-02 -0.1250068947 -0.125439970  1.612462e-02
#> Fn1      -0.0263861792  2.825983e-02  0.0102674758  0.053535815  5.371041e-02
#> Mertk     0.0636284756  7.375500e-02  0.0038191254  0.140573724  1.177747e-01
#> Adgrl2   -0.0228908889 -7.787807e-02 -0.0810190261 -0.055962182 -1.500475e-01
#> Fzd2     -0.0043931382  3.327012e-02 -0.0681692424 -0.068827869  7.152434e-02
#> Aldh1l1   0.0710862542 -7.769703e-02  0.0582722364 -0.140624588 -4.983157e-02
#> Adgrg6   -0.0118591507 -7.894166e-02  0.1372651343 -0.110852399 -7.310954e-02
#> Egfr      0.0322822638  8.828886e-02 -0.0575830224  0.045389255 -3.166876e-02
#> Kit      -0.0063283850  4.850125e-02  0.0058902801  0.006787918 -4.666146e-02
#> Ptgdr    -0.0033795743  7.205373e-02 -0.0338538620  0.010687341  2.218572e-02
#> Gad1      0.0649317004  1.052728e-01 -0.0169077529 -0.087712485 -4.638314e-02
#> Tyro3    -0.1936872100  8.286322e-02  0.0596594836  0.158670818 -1.697447e-01
#> Atp13a5   0.0536887501 -7.139742e-02 -0.0006019162  0.032278164  3.367556e-02
#> Ddr2     -0.0118138792  7.599040e-02  0.0981873588 -0.011273135 -5.016877e-02
#> Rspo3     0.1926614623  2.216777e-01 -0.1237669286  0.190032935 -1.532177e-01
#> Arhgap29  0.0512842017  9.375010e-02  0.0144832564 -0.055482717  7.913907e-04
#> Fzd7     -0.0348546237 -7.435300e-02 -0.1377184601 -0.034325478  6.582313e-02
#> Slc47a1   0.0337073209 -4.600745e-02  0.0360188574 -0.002719568  7.251633e-03
#> Ptger3   -0.1665172671  6.925160e-02  0.0112721993 -0.057882229  3.436207e-02
#> Bdkrb1   -0.0149827331  3.956890e-02  0.0256329102  0.080174603  1.338152e-01
#> Traf4     0.1010347149 -4.021194e-02 -0.1354731048  0.051532783 -1.349484e-02
#> Cx3cr1    0.0009525478 -1.017464e-01  0.0049169613 -0.031228771 -1.107590e-01
#> Anxa11    0.1317304674 -5.213404e-02 -0.0008196147  0.104542851  9.760599e-02
#> Adgrb1    0.0569615285 -1.567489e-01  0.1746398448  0.167423492  6.489188e-02
#> Lpar1     0.0635439589 -1.292604e-01  0.0833577119 -0.042971513  2.382378e-02
#> Gpr17    -0.0424124024 -4.348071e-02  0.0262955726  0.025745022  8.425356e-02
#> Cxcl12    0.0010679019  4.864325e-02  0.0606862789  0.094669791  1.066750e-01
#> Epha4    -0.0821875289 -9.604508e-02  0.0612775936  0.120227765 -9.518840e-02
#> Gpr182   -0.0479715697  5.451215e-02  0.0271839533  0.042579190  8.562556e-03
#> P2ry14    0.1085034671 -5.430043e-02 -0.0155609584  0.050346184 -1.591596e-01
#> Hcar1    -0.0067979095 -3.439027e-02 -0.0022340629 -0.100960193 -8.404609e-02
#> Ephb1     0.0371327572 -5.541361e-02 -0.0188839748 -0.140323806 -2.243897e-02
#> Grm3      0.0389587964  1.446795e-01  0.0760903847  0.065248793 -5.862115e-02
#> P2ry1     0.0009032442 -5.571599e-02 -0.0329558709 -0.078559184 -2.140956e-01
#> Ptk7      0.1021790718  3.947358e-02 -0.1292614587  0.205451999 -1.922064e-01
#> Slco1a4  -0.1230216987  1.620591e-02 -0.0164715384  0.075624971 -7.504246e-02
#> Insrr    -0.0618564389  7.917756e-02 -0.0133765712 -0.053179434 -6.474554e-03
#> Cmklr1    0.0876965432 -1.905926e-01  0.0410382644  0.036860903 -1.367721e-01
#> Fzd6     -0.0606310055 -4.110305e-02 -0.0606122265  0.085063856 -1.423208e-01
#> S1pr5    -0.0333697225 -1.651912e-01 -0.2398338827  0.079263455  9.648839e-02
#> Pdgfrb    0.0722589193  6.142832e-02 -0.0268860101  0.071009120 -4.138239e-02
#> Flt1      0.0094090193 -3.079724e-02  0.0182186890 -0.075639673  1.047349e-03
#> Adgrl4   -0.0209377846  3.113586e-03  0.0128197093  0.070877993  5.843472e-02
#> Lpar6    -0.0402961268  7.686132e-02 -0.1282588895  0.008005590 -1.463135e-01
#> Epha6     0.1305479186  1.104275e-01 -0.1029818180 -0.055884161  1.073548e-01
#> Emcn     -0.0470831763  7.510201e-02  0.0362258487 -0.038194179 -2.105266e-01
#> Cldn5     0.0565542902  2.510552e-02  0.0315876240 -0.009298534  7.189559e-02
#> P2ry12    0.1143582937 -3.988627e-02 -0.0035901726  0.001953338  8.302300e-02
#> Adgrf5   -0.0461115669 -2.655683e-02 -0.0344487892 -0.023655936 -4.777138e-02
#> P2yr13    0.0125318115  5.569178e-02 -0.0420937780 -0.015805057  4.400681e-02
#> Adgre1    0.0117089575  1.161404e-01  0.0513334851  0.058824367  6.150708e-02
#> Cx3cl1    0.0525073828  2.093352e-02 -0.0754721673  0.169348562 -1.571408e-01
#> Plxnb3   -0.0205279486 -7.604818e-02 -0.0924020758 -0.006464499 -9.795533e-02
#> Flt4      0.1073713796 -1.297346e-02 -0.0427496857 -0.127412189 -1.227490e-01
#> Slc17a7   0.0565152861  2.272088e-01  0.0271522871 -0.229408843 -4.701083e-02
#> Cd300c2   0.0274907928  1.143450e-02  0.0065890129 -0.130221505 -7.010812e-02
#> Tek       0.0560011841  4.294065e-02  0.1335633219 -0.014078586  4.149950e-02
#> Kdr      -0.0201259418 -6.527167e-02 -0.0735287909 -0.018974185 -7.516299e-02
#> Kcnj8     0.0372905862 -1.116525e-02 -0.0252264071  0.044301430 -6.266965e-05
#> S1pr3    -0.0299521998  1.025287e-01  0.0882538463 -0.159986219 -2.502918e-02
#> Tie1     -0.0717360114  2.639144e-02 -0.1375540330  0.157961502  1.553215e-04
#> Pdgfra    0.0233506937  8.200833e-02  0.0038740056  0.095441443 -9.966319e-02
#> Baiap2   -0.4645124859 -6.708663e-03 -0.0683163507  0.095760104  4.075181e-02
#> Calcrl   -0.0755337762  2.884843e-02 -0.1971094832 -0.147954534  1.646196e-01
#> Adrb2     0.0232551104  2.182670e-02  0.0442128864 -0.031119813  7.749773e-03
#> Ccr2      0.0187758578  1.423078e-01 -0.0401214290  0.009916639  1.618989e-01
#> Alk       0.0094736307 -2.479994e-02 -0.0290829866  0.131559455  7.399575e-02
#> Tacr3     0.0475557748  2.828127e-02 -0.0447900242 -0.074897727 -1.551180e-01
#> Erbb3    -0.0116597367 -7.930685e-02  0.1488984855 -0.011857314 -2.676202e-02
#> Pcdh15   -0.0269552105  5.885912e-02  0.1059472583 -0.106230546  6.587346e-02
#> Grm7      0.0826025860  2.463791e-01 -0.1404234949  0.082048046 -3.615954e-02
#> F2r       0.1026273597 -4.818283e-02  0.0852606440  0.082413081  1.522432e-01
#> Bdkrb2   -0.0542236247 -6.360083e-02  0.0038745014 -0.025688396  3.332960e-02
#> Adgrv1   -0.1021722586 -1.422461e-01  0.0437448145 -0.056937217 -5.939909e-02
#> Gprc5c    0.0495495077 -1.119429e-01  0.0529993738 -0.084594579  4.060084e-02
#> Tbxa2r   -0.0121577529  7.251028e-03 -0.0883168339  0.064150475 -3.959664e-03
#> Ackr1     0.0079071318  5.988393e-02  0.0151373969  0.031453858  8.095278e-03
#> Lpar2     0.0043291299  8.080011e-02 -0.0356883105 -0.054470181 -1.099391e-02
#> Myh11    -0.0567735403  7.492579e-02 -0.1033736082 -0.045153914  5.432581e-02
#> Musk     -0.0627212129  8.387976e-02  0.0950492391  0.076878746  6.558108e-02
#> Cnr1     -0.0356711740 -5.338342e-02  0.0150921884 -0.018300402 -7.110529e-03
#> C3ar1    -0.0302378107 -2.663406e-02  0.0970212512  0.013354996  1.387947e-02
#> S1pr4     0.0777441924 -8.961595e-02 -0.0089304346 -0.026649657 -5.290134e-02
#> C5ar1     0.0334688763 -9.575626e-02  0.0356289138  0.058512222 -5.330371e-02
#> Fpr1      0.0178616196  6.087678e-02 -0.0822492653  0.025762868  1.574356e-01
#> Sctr     -0.0927803997  2.562672e-02  0.1087190230  0.024505202 -1.272342e-01
#> Gpr158    0.2804129926 -1.019917e-01  0.0460595008  0.011958022 -1.576415e-01
#> Cxcr4    -0.0124775636 -1.470519e-02  0.0210273618  0.013932847 -5.098411e-02
#> Hrh2      0.0527114067  1.065130e-01 -0.0018334120 -0.032959941 -3.524109e-02
#> Slc17a6   0.0356926463 -1.842255e-02 -0.1074389264 -0.015823678  8.473616e-02
#> Ppp1r3g  -0.0880604154  7.780899e-02  0.1949952894 -0.178453914  5.251934e-02
#> Pln      -0.0454816248  5.586009e-02 -0.0074355584  0.082752732 -4.942930e-02
#> Grin2b   -0.1556732114 -1.328897e-01  0.0514727255  0.102723982  6.283657e-03
#> Taar7e   -0.0604679604 -4.507736e-02 -0.0121886825  0.016353812  1.261960e-01
#> Ptger2   -0.0399916191 -4.134145e-02  0.0832987494 -0.094119195  3.060327e-02
#> Mc4r      0.1444646087 -1.640418e-02  0.0906481710  0.043195372  1.538470e-01
#> Ghsr     -0.0199047909  4.445657e-02 -0.0162983411 -0.028989517 -2.208633e-02
#> Nmbr     -0.0466640465 -6.363597e-02  0.0567610241  0.083868530 -6.956039e-02
#>                 Dim.91        Dim.92        Dim.93        Dim.94       Dim.95
#> Mlc1      5.274630e-02  0.1119067244 -0.0058843186 -0.1260245979 -0.062133638
#> Gprc5b    7.451196e-02 -0.0725239516 -0.0177110790  0.0422678106 -0.071748323
#> Gfap     -5.426800e-03 -0.0009118004  0.0203838019  0.0130710924 -0.058933794
#> Ednrb     1.270626e-01  0.1975129564  0.0128232313 -0.0401348038  0.069795811
#> Sox9      5.300940e-02 -0.0635346464  0.0548853394  0.0165461293  0.159258768
#> Aqp4     -1.517101e-02  0.0242932969  0.0024132074  0.0041561978  0.106669459
#> Gjc3     -9.228729e-02  0.1188491227  0.1082725892  0.0010672864  0.038196259
#> Sox8      7.469424e-02 -0.0440096699 -0.0868163694 -0.0280494469 -0.032285235
#> Ntsr2    -7.869387e-02 -0.0087441775  0.0994052047 -0.0470564988 -0.144997227
#> Smo      -4.865835e-02  0.0229379884 -0.1074756153  0.0354601048  0.116596708
#> C1qb     -2.074106e-02 -0.2393448345  0.0478761536 -0.0007524227 -0.014477896
#> Olig1     2.768440e-02 -0.1600840106  0.0088878639 -0.0040873489  0.022958611
#> C1qa      1.876587e-02  0.0138978653 -0.1212664358 -0.0558055109 -0.142545337
#> Pth1r    -1.809017e-01 -0.0452984472  0.0533957458 -0.1415904704 -0.004328204
#> Gabbr2   -2.182466e-02 -0.1128847191 -0.2304138433  0.1243715447  0.033183363
#> Timp4    -7.359871e-02 -0.0360900616 -0.0049517074 -0.1501054501  0.090362088
#> Abcc9     8.776331e-02  0.0521360242 -0.0085283136  0.1391603416 -0.022712588
#> Csf1r     5.100531e-02  0.0336142928 -0.0756824900  0.0037381114  0.020710353
#> Ntrk2    -2.417711e-01 -0.0812715030 -0.0043631322 -0.0081213750 -0.056854403
#> Adgrg1    1.346017e-01  0.1223961668 -0.2295753563 -0.0956746527 -0.090149156
#> Ntrk3    -2.374724e-02  0.0825801855  0.0551206233 -0.0290736291 -0.130174134
#> Erbb4    -3.835613e-02  0.1237293510  0.0517807023  0.0236626175 -0.100207753
#> Selplg    1.132267e-02 -0.0604731000  0.0723855567  0.0915252382  0.056802808
#> Cspg5    -1.119734e-01 -0.0693898022 -0.0016051719  0.0264069705 -0.095290874
#> Dlk1      4.919871e-02 -0.1741299554  0.0699417797  0.0420140222 -0.008967707
#> Gpr37l1   9.515550e-02 -0.0730644077  0.0446836441 -0.1253609433  0.053643619
#> Fgfr3     8.425444e-02  0.0039412239  0.0165419726  0.1590987135  0.146860270
#> Slc25a18 -8.814109e-02 -0.0135399639  0.0272595990  0.1088374133  0.056437595
#> Igf1r    -4.728995e-02  0.1028665732  0.2451292333 -0.1436671287  0.033086226
#> S1pr1     3.220078e-02  0.1448388548  0.1727089120  0.1872601124 -0.065810688
#> Grm5      6.983273e-02  0.0348919967 -0.0362557012 -0.1906023454  0.076228672
#> Axl       1.282342e-02  0.0774643176 -0.0002670706  0.0420034959  0.065182132
#> Efemp1   -1.303980e-01  0.0291655882 -0.0676869394  0.1547113193  0.187009834
#> Adgrb3   -3.224509e-02 -0.0544250128  0.0636919755 -0.0352234089  0.030183741
#> Fn1       1.095986e-02  0.0106850902  0.0123097978 -0.0392558434 -0.059979499
#> Mertk    -2.603184e-02  0.0188830892 -0.0363736098  0.0531165931  0.065029966
#> Adgrl2    6.419857e-02  0.0192476777  0.0609166898 -0.0268072961 -0.085087072
#> Fzd2      8.308113e-02 -0.0315091534 -0.0327257804  0.1299755197 -0.034626714
#> Aldh1l1   1.701282e-01 -0.0218071514 -0.1163273732 -0.0991568679  0.113192050
#> Adgrg6   -1.381625e-02 -0.0163830487 -0.0108848847 -0.0801376177  0.093141983
#> Egfr      9.556956e-02  0.0637854932 -0.0820240368  0.1227685775 -0.234172750
#> Kit       1.397337e-02  0.0074008920 -0.0111842346 -0.0473228962  0.040086813
#> Ptgdr    -1.496378e-01  0.1521258459  0.0043817332  0.0317115304  0.022757113
#> Gad1     -8.320921e-03 -0.0205413619  0.0208210785  0.0027575052  0.052196651
#> Tyro3     4.202130e-02 -0.0118759845 -0.1515579464 -0.0986512932  0.016103211
#> Atp13a5   5.137613e-02  0.0122029177  0.0166656726 -0.0367414591 -0.098132582
#> Ddr2      1.067384e-03 -0.0715132707 -0.0892093482 -0.0760200095  0.057334832
#> Rspo3     3.153281e-02 -0.1485852682 -0.0797618400  0.1017012014 -0.126598079
#> Arhgap29  3.673274e-02 -0.0313719339 -0.0092522089 -0.1041883214 -0.098033034
#> Fzd7     -8.768548e-02 -0.0556027811 -0.0340580667  0.0854028316  0.011053845
#> Slc47a1  -1.049590e-02 -0.0380321766  0.1020534531 -0.0740588261  0.064150133
#> Ptger3    8.999965e-02  0.0201227608 -0.0866566116  0.0150350012  0.068411317
#> Bdkrb1   -3.517196e-03  0.0177256164 -0.1910225702 -0.0084693673 -0.002411413
#> Traf4    -3.597948e-02  0.0169164589  0.1174897496  0.0671280949  0.185864850
#> Cx3cr1   -5.266623e-02  0.0399290009  0.1858021886  0.0158711747  0.111509837
#> Anxa11    3.333925e-02 -0.0208656309  0.0301249996 -0.0459639935 -0.052587851
#> Adgrb1    9.867209e-02 -0.2357833506 -0.0256168656  0.1360881588 -0.015569375
#> Lpar1     2.985648e-02  0.1592898623  0.2317965357  0.0136643880  0.178270900
#> Gpr17    -1.592767e-01  0.2122786878 -0.0493877360 -0.0910875088 -0.004874026
#> Cxcl12    1.513376e-02 -0.0099646162  0.0797348008 -0.0463832317 -0.040245633
#> Epha4    -4.408341e-02  0.0771809879 -0.1840034099  0.1428032845  0.042768029
#> Gpr182    7.206805e-02 -0.0692460810  0.0941783248  0.0670536943  0.009681566
#> P2ry14   -1.366635e-01 -0.0484745097  0.0587505754  0.1375289381 -0.091776111
#> Hcar1    -1.679301e-01 -0.0291004491 -0.0604382372 -0.1695048047 -0.113575750
#> Ephb1     5.449130e-02 -0.0570568594  0.0088434925 -0.0410839852  0.062984098
#> Grm3      1.422796e-01  0.0382414120 -0.1080238100 -0.0181992123  0.132527789
#> P2ry1    -1.234986e-04  0.0352800912  0.0061337002  0.0148423810  0.040628383
#> Ptk7     -3.400042e-02  0.1043124267 -0.0023697917 -0.0434795872 -0.127352696
#> Slco1a4  -1.102402e-01 -0.0510245545 -0.0154378755  0.0652769290  0.127281908
#> Insrr    -1.279034e-01 -0.0198141057 -0.0402604398  0.0917762751  0.120392818
#> Cmklr1   -6.111989e-02  0.0239326991  0.1557921105 -0.0467046857 -0.031457352
#> Fzd6      2.392842e-01  0.1070139799  0.1032530179  0.0594508148 -0.117127669
#> S1pr5    -1.698502e-01  0.0064873071 -0.0314512754 -0.0047582822 -0.088842584
#> Pdgfrb   -8.903590e-02  0.0554026147  0.0112335976 -0.0554802232  0.097785036
#> Flt1     -8.397945e-02  0.1104478313 -0.1445429372 -0.0585623138  0.085627628
#> Adgrl4    5.147395e-02 -0.0077315055 -0.0228087263  0.1125072990  0.015768241
#> Lpar6     2.688989e-02  0.0025936378 -0.0909584982 -0.0205692378  0.023886774
#> Epha6    -8.426374e-02  0.0083902484  0.0610022002  0.0535833669  0.043927727
#> Emcn     -3.379956e-02 -0.1881030057 -0.1108758191  0.0219499761  0.040543646
#> Cldn5     5.164176e-03 -0.0582697060  0.0315810714 -0.0780171074 -0.009205243
#> P2ry12   -3.672288e-04  0.0195319771  0.0371205083  0.0553671931 -0.054466839
#> Adgrf5    3.637698e-02  0.0418984353  0.0651674492  0.1303545172 -0.023513050
#> P2yr13   -1.053792e-02  0.2155203696 -0.1715896097 -0.1840113796  0.026579646
#> Adgre1    1.579639e-02  0.1910967722 -0.0406083345 -0.0335323958 -0.060401049
#> Cx3cl1    1.264855e-01 -0.0212992628  0.1466435162 -0.1492039960  0.055354754
#> Plxnb3    2.288169e-02  0.1594962174 -0.1326319356 -0.1112995400 -0.008911806
#> Flt4      2.436691e-03 -0.0625747141  0.1160129047 -0.1579802723 -0.025707302
#> Slc17a7  -2.162611e-02  0.1501026508  0.1773487521  0.0284518061 -0.002662220
#> Cd300c2   9.373069e-03  0.0455778645  0.0651040413 -0.0580099884  0.013556195
#> Tek       1.179705e-01  0.0442479816 -0.0622206196  0.0017044543 -0.073825263
#> Kdr       2.954364e-02 -0.0778192837  0.0419985628  0.1193363711  0.012406760
#> Kcnj8    -1.139091e-01 -0.0112078354  0.0632968271 -0.0711670943 -0.025603391
#> S1pr3     1.651888e-01 -0.0941163033 -0.0543558259 -0.0878114038  0.060274450
#> Tie1      2.183940e-02 -0.0929299554  0.1221934973  0.0714904304 -0.035429824
#> Pdgfra    4.470313e-02 -0.0704080579 -0.0366466912 -0.0660518979  0.070267173
#> Baiap2   -5.007352e-02  0.0964096735  0.0653049088 -0.0439186303  0.099053514
#> Calcrl    5.086396e-02 -0.0443910277 -0.0632429601 -0.0755402623 -0.170827488
#> Adrb2    -8.531171e-02 -0.0235390834  0.0277281774 -0.0281566993 -0.012074353
#> Ccr2     -1.111422e-02  0.0798895460 -0.0142434512  0.0499987246  0.051588246
#> Alk       8.818340e-02 -0.0064481907  0.1489984479  0.0272100256 -0.002052568
#> Tacr3    -2.423263e-02  0.1858740584 -0.0864598644  0.1845241189  0.011070858
#> Erbb3     8.649665e-02  0.0403412424 -0.0080201021  0.0573785690 -0.067445700
#> Pcdh15    1.793187e-01 -0.0904384341  0.1222951706  0.2295291974 -0.205263012
#> Grm7      4.082372e-02  0.0645856989  0.0246271920  0.0779872938  0.118455276
#> F2r       2.593090e-02  0.1970133776  0.1180674408  0.1078030635 -0.035225472
#> Bdkrb2    4.564745e-02  0.0071894322 -0.0718710495  0.0627660964 -0.032027913
#> Adgrv1    3.446076e-01  0.0422527952  0.0312952274 -0.1030285349 -0.094754773
#> Gprc5c    2.988676e-03  0.0616420471 -0.0758919905  0.0202860957 -0.054501685
#> Tbxa2r    1.076748e-01 -0.0119957490  0.0666507185  0.0809035397  0.074280864
#> Ackr1    -9.688354e-03  0.1109129947 -0.0213916976  0.0203904193 -0.052891145
#> Lpar2    -1.743762e-02  0.0145641239  0.0126481211 -0.0354632132 -0.110595369
#> Myh11    -1.829092e-03 -0.0306573803 -0.0995110444  0.0341511540  0.001283886
#> Musk     -6.212793e-02 -0.0801629560  0.0638048127 -0.1806913031 -0.159469306
#> Cnr1      5.976242e-03 -0.0178971737 -0.0075423455 -0.0488774634  0.055390504
#> C3ar1     3.295826e-02  0.0129418092 -0.0200485611  0.0907133802  0.096648532
#> S1pr4    -3.719727e-02 -0.0622030391 -0.1293827367 -0.0283849392  0.078226450
#> C5ar1     1.801483e-03  0.0308498187  0.0473987344 -0.0730893051  0.069828518
#> Fpr1      7.931787e-02  0.0837330351  0.0236887889  0.0098323219 -0.135110079
#> Sctr     -2.198100e-01  0.0260801526 -0.0583525288  0.1126435113 -0.251303669
#> Gpr158    2.018869e-02  0.0735612563 -0.1174086930  0.1017593704 -0.026547291
#> Cxcr4     2.807854e-02 -0.0252815960 -0.0357495237  0.0205471203  0.064926506
#> Hrh2     -4.505155e-02  0.0547656474  0.0717706742  0.0838867644  0.014215480
#> Slc17a6   1.118016e-01  0.0334324949  0.0303828133 -0.0459640930  0.084925433
#> Ppp1r3g  -1.845598e-01 -0.0806323697  0.0278996958  0.0034614065 -0.203229312
#> Pln      -5.207526e-02 -0.0141919704  0.0136697737  0.0119358138  0.022949312
#> Grin2b    3.785940e-02 -0.0624963454  0.1174093742 -0.1673219285 -0.129418076
#> Taar7e    5.297093e-02 -0.1448636627  0.1009128563 -0.0668147619  0.087798126
#> Ptger2    6.293152e-02 -0.0018785182  0.0015214838 -0.0097059538 -0.053563140
#> Mc4r     -2.186995e-02 -0.1983943923 -0.0134706415 -0.1139875981  0.068989559
#> Ghsr      2.851065e-05  0.0086599489 -0.0222297196 -0.0583938753 -0.002155070
#> Nmbr     -3.243908e-02 -0.0140878731 -0.0506366406  0.0631695680 -0.002616482
#>                 Dim.96        Dim.97        Dim.98        Dim.99       Dim.100
#> Mlc1     -0.0443537762  0.0360484369  0.0819819508  1.260459e-01  0.0450089853
#> Gprc5b   -0.0510558926 -0.0167780274 -0.0765372383 -5.747994e-02  0.0109242827
#> Gfap     -0.0172649627 -0.0325150875 -0.1045522993  2.849920e-02 -0.0343928321
#> Ednrb     0.1799824844 -0.0266675468  0.0126936581  1.502550e-01  0.0914827465
#> Sox9     -0.0776139391 -0.1348317883  0.0272543567 -1.218634e-01  0.0578865312
#> Aqp4     -0.0108937623  0.1450361285  0.2153831763 -5.214377e-02  0.0292030131
#> Gjc3     -0.0711227766 -0.0237886291  0.0343921640 -8.717850e-02  0.0005867661
#> Sox8     -0.0219504626  0.1839473385 -0.0055640059  8.358220e-02 -0.0472305015
#> Ntsr2    -0.0632400181 -0.0132755552 -0.0229996979  1.290156e-02 -0.1622541807
#> Smo       0.0446726332  0.0240068066 -0.1061320550 -1.462967e-01 -0.0498647005
#> C1qb     -0.0711368702  0.0638066014  0.1014940176  7.417651e-02  0.2129650839
#> Olig1     0.1893899465 -0.0113085427  0.0271378206  7.785833e-02 -0.0509245967
#> C1qa     -0.0449503731 -0.0960650048 -0.0771657285  4.181065e-02 -0.0754157023
#> Pth1r    -0.0108889896  0.0968962403 -0.0397244781 -3.021003e-02  0.1744126574
#> Gabbr2   -0.1127715258  0.1773201109 -0.1029834145  1.209036e-01 -0.0706423471
#> Timp4    -0.0469308197 -0.0136558665  0.1427075714  7.442107e-02  0.2083804252
#> Abcc9    -0.0868392638  0.0548558733  0.1813730140 -9.282117e-02 -0.1516930779
#> Csf1r     0.0597065849 -0.0116122845  0.0336615327 -1.838982e-02 -0.0626278245
#> Ntrk2     0.0889879882  0.0814695626  0.0465132494  4.193621e-02  0.0532033928
#> Adgrg1   -0.0046413805 -0.1743434429 -0.1574148804 -2.932602e-01 -0.1899499941
#> Ntrk3    -0.0935254436 -0.2637648766  0.2785446170 -2.392332e-02 -0.0058407785
#> Erbb4    -0.1687700521 -0.0341593112 -0.2247057880  1.110902e-01  0.0796625842
#> Selplg    0.0437971895 -0.0463517396  0.0465568388  6.566697e-02 -0.0708426139
#> Cspg5    -0.0097326391  0.0375980393  0.1274219462  7.434923e-02 -0.0581365681
#> Dlk1     -0.0550064886 -0.1046811997  0.0624809226  3.654155e-02 -0.0024350514
#> Gpr37l1   0.0557102606 -0.0889941638 -0.1141913728  1.594975e-01 -0.0369676530
#> Fgfr3     0.0586096854 -0.0269485012 -0.0181944486 -6.419439e-02  0.1628006771
#> Slc25a18 -0.0754009255  0.1231508326  0.0387336149  4.379239e-02 -0.0008650515
#> Igf1r    -0.0071980557  0.1371319776  0.0010901707  1.028243e-01  0.1415628044
#> S1pr1    -0.0586984413  0.1770275465 -0.1479985976 -1.284361e-01 -0.1350629013
#> Grm5     -0.0112312693  0.1778657338 -0.0605667870  1.595176e-01 -0.1533531628
#> Axl       0.0868458539  0.0655911386 -0.0048398865 -1.126509e-01 -0.1559221555
#> Efemp1   -0.0309381034 -0.1439380354 -0.0925716241  7.542845e-02  0.0478113886
#> Adgrb3   -0.0560734659  0.0039267328 -0.0026751082 -1.309427e-01 -0.0333891198
#> Fn1      -0.0239286942 -0.0205363547  0.0211027429 -2.125365e-02 -0.0460118361
#> Mertk     0.0395005414  0.0640619585  0.1031300535 -5.733631e-02  0.1335469428
#> Adgrl2    0.0195788504  0.0789741627 -0.0008308767  2.853738e-03 -0.0062170128
#> Fzd2     -0.0065199766 -0.1310735935  0.1572681321  8.776131e-02  0.0552191702
#> Aldh1l1  -0.0224101512  0.0292154700 -0.0378982746 -9.869550e-03  0.1135695271
#> Adgrg6   -0.0555596044  0.0919334192 -0.0236862783  2.818611e-03 -0.0003815807
#> Egfr     -0.1078294613  0.1540900612  0.1981852096 -1.919934e-02  0.0780892047
#> Kit       0.0523865550 -0.0386807889  0.0162609700 -1.247745e-02  0.0111076131
#> Ptgdr     0.1490205337 -0.0648832054 -0.0358539783  1.555095e-01 -0.1691839548
#> Gad1      0.1130041785  0.0439577095  0.1340075342 -6.451207e-02 -0.0300128673
#> Tyro3     0.0373603761  0.1074132990  0.1054368777 -4.662024e-02 -0.0365530052
#> Atp13a5   0.0073141075  0.0294909094  0.0357624918  1.460249e-02  0.0689017805
#> Ddr2     -0.0841406286  0.1473669490 -0.0089520103 -1.673733e-01  0.0827914374
#> Rspo3     0.0742247994  0.2529983374 -0.0580867643 -6.847477e-03 -0.0299330728
#> Arhgap29 -0.0269153620 -0.1034054972 -0.0060879314  3.061664e-02 -0.0037196932
#> Fzd7      0.0826427421 -0.0354264650  0.1027051543 -8.486209e-02 -0.0869939679
#> Slc47a1   0.0377543892 -0.0122535769 -0.0236616772 -9.365409e-02 -0.0203153213
#> Ptger3   -0.0761078960  0.0401885677 -0.0211771590 -1.105876e-01  0.1265538944
#> Bdkrb1   -0.0360341989  0.0180912458 -0.0813510345  3.149664e-02 -0.0125204111
#> Traf4    -0.0841528360  0.0417908160 -0.0470187449 -5.853414e-03  0.0402492851
#> Cx3cr1    0.0121677778  0.0283883732  0.0090845478 -7.015568e-02 -0.0086359019
#> Anxa11   -0.1266526962 -0.0901204568  0.1300161597  4.910297e-02 -0.0988169775
#> Adgrb1    0.0715700958  0.0673534814 -0.0393200976 -1.013340e-01  0.0162896611
#> Lpar1    -0.0002344535  0.0775491634 -0.0357163481  7.684334e-02 -0.1244453280
#> Gpr17     0.0571312823 -0.0167074981  0.1165888236 -1.667889e-01 -0.0238835701
#> Cxcl12    0.1057562688  0.0050510973  0.1631412288  4.178168e-02 -0.0218110911
#> Epha4     0.0391504682  0.0103309385 -0.0521921360  2.497589e-01  0.0326497811
#> Gpr182    0.0126087893  0.1296180784  0.0151222552 -7.079531e-02  0.0402807391
#> P2ry14    0.1392576242  0.0009081532 -0.1124062478  9.233882e-02 -0.1015120121
#> Hcar1    -0.0067673809  0.0410951436 -0.0203082511  1.203454e-01  0.1064953338
#> Ephb1     0.0149729283 -0.0202305784 -0.0350631704 -3.970236e-02 -0.1435495491
#> Grm3     -0.0594710151 -0.1637695938 -0.1229371505  6.062457e-02  0.0349878895
#> P2ry1    -0.1005179917  0.1687439529 -0.0487013462 -9.843553e-02  0.0611132939
#> Ptk7      0.0957404922 -0.0178864154 -0.0425020642 -7.592525e-02  0.0114444663
#> Slco1a4  -0.0626315893  0.0201931781  0.0744170417  9.867970e-02 -0.0053665358
#> Insrr     0.0944776078  0.0335998295  0.0432814485 -5.041559e-02 -0.0815594033
#> Cmklr1   -0.0783381406  0.0509605751 -0.1146788289 -1.831444e-02 -0.0341116091
#> Fzd6      0.1052248180  0.0788448872 -0.0421288772 -1.087229e-01  0.0585974004
#> S1pr5    -0.0013298678  0.0368014566  0.0470516154 -8.905017e-02  0.0877678767
#> Pdgfrb   -0.1018702817 -0.0594929075  0.0011852843  9.373763e-02 -0.0681029985
#> Flt1     -0.0794881609 -0.0767376686 -0.0352270387  1.701944e-02 -0.0593478010
#> Adgrl4    0.0715719036 -0.0024930768 -0.0026283303 -7.695242e-02 -0.0081116497
#> Lpar6    -0.0338539052 -0.0699560815 -0.1013519424  1.572401e-02 -0.0209834505
#> Epha6     0.1292911044  0.0639261186 -0.0787368065 -7.881928e-02  0.0730507215
#> Emcn     -0.0630136885 -0.0387701346 -0.1296581708 -2.786186e-02 -0.0795758492
#> Cldn5     0.0089685139  0.0378101412  0.0372486792  5.591290e-03  0.0116931295
#> P2ry12    0.0407785955 -0.0067044142 -0.0493437175  1.554941e-02 -0.1460416692
#> Adgrf5    0.0356186631 -0.0929036549 -0.0431651800 -2.943058e-02 -0.0265416805
#> P2yr13   -0.1024577086  0.1104307839 -0.0186240317 -1.499583e-01  0.2366327278
#> Adgre1   -0.0207542755  0.1252825896 -0.0217732142  2.833754e-02 -0.0388424267
#> Cx3cl1   -0.3294128886  0.0023821356  0.2061062819 -2.316771e-02 -0.2453750441
#> Plxnb3    0.1697384800  0.1661675573 -0.0152867680  8.637727e-02 -0.0701051213
#> Flt4      0.0586426204  0.0176883428 -0.0125178126  3.461665e-02 -0.0392505043
#> Slc17a7   0.0828733051  0.0429671987 -0.1974277477 -6.446599e-02  0.1643070653
#> Cd300c2  -0.0481613197 -0.0563445727 -0.0710774534  7.344774e-03 -0.0100193949
#> Tek      -0.0089852611  0.0414927826  0.0590540015 -1.597511e-02  0.0268458258
#> Kdr       0.0779024612  0.0734437579 -0.0069344954  1.293320e-02  0.0015974350
#> Kcnj8     0.0818562748 -0.0584210918 -0.1080648007  7.424314e-02  0.1278848916
#> S1pr3     0.1318715326  0.0812680530 -0.0165760443 -8.612860e-02 -0.0265361090
#> Tie1      0.0033508741  0.1083100692 -0.0006694247  2.620638e-02  0.0579725541
#> Pdgfra   -0.0387369696  0.0588450248 -0.0787371045 -2.944948e-02 -0.1049359760
#> Baiap2   -0.0775217698  0.1349416427 -0.1636373601  1.108546e-01 -0.1079669366
#> Calcrl    0.1419570347  0.0208696070 -0.0293084541  1.669668e-01  0.0357484666
#> Adrb2    -0.0365630186 -0.0082632953 -0.0670394928  6.155158e-02  0.0227936987
#> Ccr2      0.0858909799 -0.0021885373  0.0625329152 -2.820142e-02  0.0099452840
#> Alk       0.0458290549 -0.0734565716 -0.1648546419  5.582668e-02 -0.0792551027
#> Tacr3     0.0265660569 -0.0436933519  0.0850627227  9.230092e-02  0.0687709599
#> Erbb3     0.1245836146  0.1412833680  0.0164346809  1.122492e-01 -0.0665527368
#> Pcdh15   -0.2529142945 -0.1004256139 -0.1432620596  1.004588e-01  0.2194278503
#> Grm7     -0.1397368781  0.1089594413  0.0379568219  1.443681e-02 -0.0322724861
#> F2r      -0.0423929786  0.0566388736 -0.0074588355  1.282994e-02  0.0393546109
#> Bdkrb2    0.0781244052  0.0162706420 -0.0392946792 -9.185904e-03  0.1108206463
#> Adgrv1   -0.0356076159  0.0738471856 -0.0006103067  9.597895e-02  0.0121626521
#> Gprc5c   -0.2042111942 -0.0003886170 -0.0891583759  8.981869e-02 -0.0085222955
#> Tbxa2r    0.0088643166  0.0266243067  0.0670353931 -7.072588e-02 -0.1360094300
#> Ackr1    -0.0123965578 -0.1484398276  0.0494395270 -4.358139e-02  0.0026337024
#> Lpar2    -0.0224920176 -0.1120428877 -0.0551356136 -3.575251e-02  0.0088337743
#> Myh11     0.0404946186  0.0164047386 -0.0386613025  2.024687e-02 -0.0207320428
#> Musk     -0.0524175931  0.0439845020 -0.0106651062 -9.185905e-02 -0.0704663974
#> Cnr1     -0.0508017667  0.0555751164 -0.0332689232  6.523213e-03 -0.0693199266
#> C3ar1     0.1046549965  0.0508510489  0.0800600990 -3.385654e-02 -0.0109808954
#> S1pr4    -0.0717778678  0.0565913811 -0.1038866351 -1.688067e-02  0.0660013158
#> C5ar1    -0.0336764016  0.0003741751 -0.0131256422 -9.364569e-02  0.0141209369
#> Fpr1      0.0418202715  0.1105538549  0.0453254973  3.427520e-02  0.0066593880
#> Sctr     -0.1433701071  0.0896402281 -0.1137159324 -2.522357e-01 -0.0207737837
#> Gpr158    0.0562321374 -0.0563950797  0.1171726660  4.753825e-02 -0.0126591675
#> Cxcr4     0.0118897498 -0.1273500733 -0.0736292578  9.587281e-05 -0.0497375321
#> Hrh2     -0.0696668100 -0.0344627831  0.0156450293 -1.724896e-02  0.0246493820
#> Slc17a6   0.0333474238  0.0239279656  0.0496821502  1.116024e-01 -0.0052144861
#> Ppp1r3g   0.0152166395  0.0842415215  0.0323072063  8.383231e-02 -0.2180193222
#> Pln       0.0560646403 -0.0693041040  0.0316120048 -3.325110e-02  0.0144415377
#> Grin2b    0.3086303995 -0.1369938155 -0.0702822115 -1.924546e-01  0.0952752006
#> Taar7e    0.0299564845  0.0113191149 -0.1575437408 -7.225802e-02 -0.0143840271
#> Ptger2    0.0687272492 -0.0360582887 -0.0043759260  1.268787e-02  0.0203538675
#> Mc4r     -0.0853855671  0.0217886780  0.0046874230 -3.175744e-02 -0.0417995305
#> Ghsr      0.0217415657  0.0229802934 -0.0204775738  2.456220e-02  0.0040153451
#> Nmbr     -0.0143240610 -0.0464849471 -0.0352151903 -1.932095e-02  0.0324894853
#>