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Deconvolution

Estimate cell type proportions per spot.

dwls()
Deconvolve spots into cell type proportions
dwls_stream()
Deconvolve spots read in windows

Reference profiles

Build the signature matrix from single-cell data.

dwls_signature()
Build a DWLS signature matrix

Package

spatialDWLS spatialDWLS-package
spatialDWLS: cell type deconvolution of spatial spots