Identifies cell-to-cell Interaction Changed Features (ICF), i.e. genes that are differentially expressed due to proximity to other cell types.
findCPG(...)
Arguments passed on to findICF
gobject
giotto object
feat_type
feature type
spat_unit
spatial unit
expression_values
expression values to use
selected_feats
subset of selected features (optional)
cluster_column
name of column to use for cell types
spatial_network_name
name of spatial network to use
minimum_unique_cells
minimum number of target cells required
minimum_unique_int_cells
minimum number of interacting cells required
diff_test
which differential expression test
mean_method
method to use to calculate the mean
offset
offset value to use when calculating log2 ratio
adjust_method
which method to adjust p-values
nr_permutations
number of permutations if diff_test = permutation
exclude_selected_cells_from_test
exclude interacting cells other cells
do_parallel
run calculations in parallel with mclapply
set_seed
set a seed for reproducibility
seed_number
seed number
cell-to-cell Interaction Changed Genes